Click here to switch to the map view.

The map label for this gene is aspC [H]

Identifier: 124027913

GI number: 124027913

Start: 1057867

End: 1059024

Strand: Direct

Name: aspC [H]

Synonym: Hbut_1044

Alternate gene names: 124027913

Gene position: 1057867-1059024 (Clockwise)

Preceding gene: 124027909

Following gene: 124027914

Centisome position: 63.45

GC content: 59.33

Gene sequence:

>1158_bases
TTGACGTTTATTGCTAAGGCTCGGGAGGCCGCCGCGCGTGGCCTCGACGTCATTAGTTTCGGTGTTGGACAGCCCGACGC
GCCTACGTTTCCGCATATTGTTGAGGCTGGTATACGGGCTCTTGAGGAGGGGTTTACAGGGTATACTGAGACTCAAGGAA
TTCCCGAGCTTCGGAAGGCAATAGCAGATTATCTGAACGAGCGGTATGGGGCGGGTGTTTCGGCCGACGAGGTCATCGTT
ACGACTGGAGCTAAAACAGCACTGTTCGTGGCCATGGCCGCTGTGCTGAGGCCTGGCGACGAGGTATTGATACCGGAGCC
TAGCTACCCCTCCTACGCCTCAACAGCCCGTATCCTCGGCGCTCGGCCGGTGTTCGTGCCGCTCCGCTGGACTGGTAGGG
GCTTCGAACTCGACGTCTCAGCTGTGGAGGAGAGGCTGACAGAGCGTACGAAAATGATAGTGCTTAATAACCCACACAAC
CCCACCGGGACAGTGTTCAACGCGCAGGCTGTCGAAGAGCTTGTTGAACTCGCCTCCCGGCGGGGCATAGCAGTACTGGC
TGACGAGATATACGACAACTTCGTCTACGAGGGCAGGTTCCGCAGCGTCCTCGAGTCCGCCAGATGGAGGGATGTTGTTC
TCTATGTTAACGGACACTCTAAGACATTCTCGATGACAGGGTGGAGGCTTGGCTGGCTCGTAGCCGACCGGAGGCTCATC
CCGCTGCTCCGCTTTATAGCGGAGAACGTGTACAGCTGCGCGCCGAGCATCAGCCAGCGCGCTGGCGTAGCCGCGCTACG
GGGTCCGTGGGAGCCGGTCCGGGAAATGGTTGAGGAGTTCCGCCAGCGCCGCGACATCATGGTCGAGGAACTCTCGAAGA
TACCCGGCGTCGAGACCTACAAGCCGCAGGGCGCGTTCTACGTATTCCCTCGGCTTGCCCGGCTGGTAGAACAGCTCGGC
ATGACTGTTGAGGAGCTGGTTGAACACATGATCTACTCTAGGGGCGTCGTAATGATACCGGGCAGCGTGTTCCCCGACAA
GGCCGGGGCGTTGCATGTACGGCTTAGCTATGCGCTGCGGCCAGAGAGGATAAGGGAGGGCATGAGGAGGTTCCGGGAGG
AGGTCGAGAACCTCCTGGAGGAGAAGGCGAAGAGATAA

Upstream 100 bases:

>100_bases
GCATCGCGTTTCCTTCCCATAATCCCTCCTGGAGGCTGGCCAGGGCTTGGCGCTACATGATATTGTTCGTTCCGAGGTGT
TGCCTGGACGTGCTACTACG

Downstream 100 bases:

>100_bases
GCGGGGGAGGATAGGCGTAATTAAGGCGCCAGGCAACCCCTCCCCTCCAATGGCGACTGTTGACAAGCTGCATAGTAGGA
TAGCCGGGGTGACAATAGGT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTFIAKAREAAARGLDVISFGVGQPDAPTFPHIVEAGIRALEEGFTGYTETQGIPELRKAIADYLNERYGAGVSADEVIV
TTGAKTALFVAMAAVLRPGDEVLIPEPSYPSYASTARILGARPVFVPLRWTGRGFELDVSAVEERLTERTKMIVLNNPHN
PTGTVFNAQAVEELVELASRRGIAVLADEIYDNFVYEGRFRSVLESARWRDVVLYVNGHSKTFSMTGWRLGWLVADRRLI
PLLRFIAENVYSCAPSISQRAGVAALRGPWEPVREMVEEFRQRRDIMVEELSKIPGVETYKPQGAFYVFPRLARLVEQLG
MTVEELVEHMIYSRGVVMIPGSVFPDKAGALHVRLSYALRPERIREGMRRFREEVENLLEEKAKR

Sequences:

>Translated_385_residues
MTFIAKAREAAARGLDVISFGVGQPDAPTFPHIVEAGIRALEEGFTGYTETQGIPELRKAIADYLNERYGAGVSADEVIV
TTGAKTALFVAMAAVLRPGDEVLIPEPSYPSYASTARILGARPVFVPLRWTGRGFELDVSAVEERLTERTKMIVLNNPHN
PTGTVFNAQAVEELVELASRRGIAVLADEIYDNFVYEGRFRSVLESARWRDVVLYVNGHSKTFSMTGWRLGWLVADRRLI
PLLRFIAENVYSCAPSISQRAGVAALRGPWEPVREMVEEFRQRRDIMVEELSKIPGVETYKPQGAFYVFPRLARLVEQLG
MTVEELVEHMIYSRGVVMIPGSVFPDKAGALHVRLSYALRPERIREGMRRFREEVENLLEEKAKR
>Mature_384_residues
TFIAKAREAAARGLDVISFGVGQPDAPTFPHIVEAGIRALEEGFTGYTETQGIPELRKAIADYLNERYGAGVSADEVIVT
TGAKTALFVAMAAVLRPGDEVLIPEPSYPSYASTARILGARPVFVPLRWTGRGFELDVSAVEERLTERTKMIVLNNPHNP
TGTVFNAQAVEELVELASRRGIAVLADEIYDNFVYEGRFRSVLESARWRDVVLYVNGHSKTFSMTGWRLGWLVADRRLIP
LLRFIAENVYSCAPSISQRAGVAALRGPWEPVREMVEEFRQRRDIMVEELSKIPGVETYKPQGAFYVFPRLARLVEQLGM
TVEELVEHMIYSRGVVMIPGSVFPDKAGALHVRLSYALRPERIREGMRRFREEVENLLEEKAKR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=359, Percent_Identity=31.4763231197772, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI169881279, Length=359, Percent_Identity=31.4763231197772, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI56713256, Length=359, Percent_Identity=29.8050139275766, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI56713254, Length=361, Percent_Identity=29.6398891966759, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI4507369, Length=350, Percent_Identity=28, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI169881281, Length=270, Percent_Identity=29.2592592592593, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI215599424, Length=410, Percent_Identity=25.609756097561, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19263340, Length=410, Percent_Identity=25.609756097561, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4885351, Length=357, Percent_Identity=26.890756302521, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI149944424, Length=223, Percent_Identity=28.6995515695067, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI187936925, Length=245, Percent_Identity=28.1632653061224, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI14211921, Length=245, Percent_Identity=28.1632653061224, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788722, Length=361, Percent_Identity=33.7950138504155, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1788627, Length=387, Percent_Identity=27.1317829457364, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=29.023746701847, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1788332, Length=346, Percent_Identity=24.8554913294798, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787710, Length=240, Percent_Identity=27.9166666666667, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI48994949, Length=373, Percent_Identity=25.201072386059, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790797, Length=342, Percent_Identity=23.6842105263158, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787909, Length=184, Percent_Identity=25.5434782608696, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=362, Percent_Identity=30.1104972375691, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71994472, Length=362, Percent_Identity=30.1104972375691, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17567369, Length=408, Percent_Identity=26.4705882352941, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17567663, Length=376, Percent_Identity=27.3936170212766, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71981209, Length=379, Percent_Identity=24.2744063324538, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI115534666, Length=352, Percent_Identity=25.2840909090909, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71981215, Length=161, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320317, Length=353, Percent_Identity=26.3456090651558, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=324, Percent_Identity=26.2345679012346, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6323118, Length=355, Percent_Identity=25.9154929577465, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28573069, Length=381, Percent_Identity=27.8215223097113, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24646114, Length=381, Percent_Identity=27.8215223097113, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28573067, Length=381, Percent_Identity=27.8215223097113, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28573065, Length=381, Percent_Identity=27.8215223097113, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI18859735, Length=351, Percent_Identity=26.7806267806268, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI45551451, Length=405, Percent_Identity=25.4320987654321, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24641770, Length=405, Percent_Identity=25.4320987654321, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641760, Length=405, Percent_Identity=25.4320987654321, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641768, Length=405, Percent_Identity=25.4320987654321, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641766, Length=405, Percent_Identity=25.4320987654321, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641764, Length=405, Percent_Identity=25.4320987654321, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21356535, Length=406, Percent_Identity=22.4137931034483, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43201; Mature: 43070

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFIAKAREAAARGLDVISFGVGQPDAPTFPHIVEAGIRALEEGFTGYTETQGIPELRKA
CCCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
IADYLNERYGAGVSADEVIVTTGAKTALFVAMAAVLRPGDEVLIPEPSYPSYASTARILG
HHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHC
ARPVFVPLRWTGRGFELDVSAVEERLTERTKMIVLNNPHNPTGTVFNAQAVEELVELASR
CCCEEEEEEECCCCCEEEHHHHHHHHHHHHEEEEEECCCCCCCCEEEHHHHHHHHHHHHC
RGIAVLADEIYDNFVYEGRFRSVLESARWRDVVLYVNGHSKTFSMTGWRLGWLVADRRLI
CCCEEHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEEECCCCEEECCCCEEHHHHHHHHHH
PLLRFIAENVYSCAPSISQRAGVAALRGPWEPVREMVEEFRQRRDIMVEELSKIPGVETY
HHHHHHHHHHHHHCCCHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KPQGAFYVFPRLARLVEQLGMTVEELVEHMIYSRGVVMIPGSVFPDKAGALHVRLSYALR
CCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEEEECCC
PERIREGMRRFREEVENLLEEKAKR
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TFIAKAREAAARGLDVISFGVGQPDAPTFPHIVEAGIRALEEGFTGYTETQGIPELRKA
CCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
IADYLNERYGAGVSADEVIVTTGAKTALFVAMAAVLRPGDEVLIPEPSYPSYASTARILG
HHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHC
ARPVFVPLRWTGRGFELDVSAVEERLTERTKMIVLNNPHNPTGTVFNAQAVEELVELASR
CCCEEEEEEECCCCCEEEHHHHHHHHHHHHEEEEEECCCCCCCCEEEHHHHHHHHHHHHC
RGIAVLADEIYDNFVYEGRFRSVLESARWRDVVLYVNGHSKTFSMTGWRLGWLVADRRLI
CCCEEHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEEECCCCEEECCCCEEHHHHHHHHHH
PLLRFIAENVYSCAPSISQRAGVAALRGPWEPVREMVEEFRQRRDIMVEELSKIPGVETY
HHHHHHHHHHHHHCCCHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KPQGAFYVFPRLARLVEQLGMTVEELVEHMIYSRGVVMIPGSVFPDKAGALHVRLSYALR
CCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEEEECCC
PERIREGMRRFREEVENLLEEKAKR
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513189; 11427726; 8026489; 3137225; 1954227 [H]