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The map label for this gene is queC [H]

Identifier: 124027914

GI number: 124027914

Start: 1059123

End: 1059986

Strand: Direct

Name: queC [H]

Synonym: Hbut_1045

Alternate gene names: 124027914

Gene position: 1059123-1059986 (Clockwise)

Preceding gene: 124027913

Following gene: 124027915

Centisome position: 63.53

GC content: 59.72

Gene sequence:

>864_bases
GTGTCTGCTCGCGGCGTCGAGCCAGTGGTTCGTAAGCCGTGCCGTGTAGTAGCAGTTGTGAGCGGTGGCCCGGACAGCAC
AGGGTACATGGTGCAGTGGCTAGCTAGGGGGTGTATGGTTCACGCGCTGAGCTTCAACTACGGCCAGAAGGGTAGCAAGG
AGCTGGAGGTTGCGGAGAAGCTCCTAGCAAGGATAAACGAGATGGCTTCCTCGCGGCCAGGCTGGGGCCGCATCCTAGAG
CACCGTGTAGTCGACATGTCGTTTATGAGGGAGTTGTGGAGAGGCACACAGCTCACCGATGAGACCGTGAAAGTTGAGGA
GGAGTACCAGCCCACCGTCGTGGTACCGATACGGAACGTCGTAATGCTATCCATCGCCACGGCCTACGCCTACAGCCTCG
CTGAGCGCTATTCCGGCGAGAACATCTACGTGGCCTATGGCGCCCACTACAACGACATCGCACCCCGGAGCGATACCTGG
GAGCCACTCTACCCCGACTGCAGCCCCGAGTGCATCGAGGCGCTGCAGACAGCGTTTAGGCTATGCCACTTCCGCGGCAG
CAGAAGAATAGAGGTATGGAGCCCGTCCAGGGAGGGTCTAACCAAGGCTGAAAACTTGAAGCGCACCTACCAGCTGATAG
GCAATCTCATCTACGAGACTTGGAGCTGCTACGAGAGTGGCAGGTTCCACTGCGGCCGCTGCAAGAGCTGCAGAAACAGG
CACCGCGCCTTCAAGGAGGCTGGGATACCCGACTGCACCCCCTACCTGCACCCGCCAGGAGACCCGAGCGAGTTCGAGGA
AAGGGTAATCGATGGCGTTAGAGTCTACGTGCATCGCAGCTGCAGCCGTGCCAGGGAATCCTAA

Upstream 100 bases:

>100_bases
AAGCGGGGGAGGATAGGCGTAATTAAGGCGCCAGGCAACCCCTCCCCTCCAATGGCGACTGTTGACAAGCTGCATAGTAG
GATAGCCGGGGTGACAATAG

Downstream 100 bases:

>100_bases
GGGCTAGGTTTATGGGGGCCAACCGGACCACTACTAGAATCCAGACTGGGGGCACAGCAAACCCTAGGCCCCCACCTCTT
TGGCTCAGAACGGAGGGTCA

Product: PP-loop superfamily ATPase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MSARGVEPVVRKPCRVVAVVSGGPDSTGYMVQWLARGCMVHALSFNYGQKGSKELEVAEKLLARINEMASSRPGWGRILE
HRVVDMSFMRELWRGTQLTDETVKVEEEYQPTVVVPIRNVVMLSIATAYAYSLAERYSGENIYVAYGAHYNDIAPRSDTW
EPLYPDCSPECIEALQTAFRLCHFRGSRRIEVWSPSREGLTKAENLKRTYQLIGNLIYETWSCYESGRFHCGRCKSCRNR
HRAFKEAGIPDCTPYLHPPGDPSEFEERVIDGVRVYVHRSCSRARES

Sequences:

>Translated_287_residues
MSARGVEPVVRKPCRVVAVVSGGPDSTGYMVQWLARGCMVHALSFNYGQKGSKELEVAEKLLARINEMASSRPGWGRILE
HRVVDMSFMRELWRGTQLTDETVKVEEEYQPTVVVPIRNVVMLSIATAYAYSLAERYSGENIYVAYGAHYNDIAPRSDTW
EPLYPDCSPECIEALQTAFRLCHFRGSRRIEVWSPSREGLTKAENLKRTYQLIGNLIYETWSCYESGRFHCGRCKSCRNR
HRAFKEAGIPDCTPYLHPPGDPSEFEERVIDGVRVYVHRSCSRARES
>Mature_286_residues
SARGVEPVVRKPCRVVAVVSGGPDSTGYMVQWLARGCMVHALSFNYGQKGSKELEVAEKLLARINEMASSRPGWGRILEH
RVVDMSFMRELWRGTQLTDETVKVEEEYQPTVVVPIRNVVMLSIATAYAYSLAERYSGENIYVAYGAHYNDIAPRSDTWE
PLYPDCSPECIEALQTAFRLCHFRGSRRIEVWSPSREGLTKAENLKRTYQLIGNLIYETWSCYESGRFHCGRCKSCRNRH
RAFKEAGIPDCTPYLHPPGDPSEFEERVIDGVRVYVHRSCSRARES

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=234, Percent_Identity=29.4871794871795, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 32727; Mature: 32595

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARGVEPVVRKPCRVVAVVSGGPDSTGYMVQWLARGCMVHALSFNYGQKGSKELEVAEK
CCCCCCCHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LLARINEMASSRPGWGRILEHRVVDMSFMRELWRGTQLTDETVKVEEEYQPTVVVPIRNV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCEEEECHHHH
VMLSIATAYAYSLAERYSGENIYVAYGAHYNDIAPRSDTWEPLYPDCSPECIEALQTAFR
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LCHFRGSRRIEVWSPSREGLTKAENLKRTYQLIGNLIYETWSCYESGRFHCGRCKSCRNR
HHHHCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
HRAFKEAGIPDCTPYLHPPGDPSEFEERVIDGVRVYVHRSCSRARES
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SARGVEPVVRKPCRVVAVVSGGPDSTGYMVQWLARGCMVHALSFNYGQKGSKELEVAEK
CCCCCCHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LLARINEMASSRPGWGRILEHRVVDMSFMRELWRGTQLTDETVKVEEEYQPTVVVPIRNV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCEEEECHHHH
VMLSIATAYAYSLAERYSGENIYVAYGAHYNDIAPRSDTWEPLYPDCSPECIEALQTAFR
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LCHFRGSRRIEVWSPSREGLTKAENLKRTYQLIGNLIYETWSCYESGRFHCGRCKSCRNR
HHHHCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
HRAFKEAGIPDCTPYLHPPGDPSEFEERVIDGVRVYVHRSCSRARES
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]