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The map label for this gene is dppB [H]

Identifier: 124027492

GI number: 124027492

Start: 579549

End: 580547

Strand: Reverse

Name: dppB [H]

Synonym: Hbut_0608

Alternate gene names: 124027492

Gene position: 580547-579549 (Counterclockwise)

Preceding gene: 124027494

Following gene: 124027491

Centisome position: 34.82

GC content: 49.15

Gene sequence:

>999_bases
TTGGCCAATCTACGCCGCTTCCTACTCCGCAGACTCATAACGTTCGTGCCAACAGTGATAGGTGTTACATTCCTCGTCTA
CATTATTGCTGTACAGATACCAGCTAATCCAGCTAGGCTATGGGCTGGCGGCGAGAAGGCTGACCCCGAGGTTGTCCAGA
GGCTTATCGAGGAGTACCACCTCAACGACCCCTGGTATGTACAATACTACTTCTTTCTCAAGAAGGTGCTGAGTGGTGAG
GCTGTGAGCCCTGTGACGCACACAAATGTCTGGGATCAGATTATGGAGAAGCTGCTGACGGTTACGCTGCCTCTAACACT
ATTCGCATTCCTATTCATAATAACTATCGGTATACCTCTAGGCATAATAGCCGCCATCAAAAGGGATACGTGGATTGATG
TTGTGATAAGAGCTTTCGCCCTCATCGGAATATCGACGCCAATCTTCTGGCTAGCCTACCTTCTAATTTTCGTGCTGCAG
CCACGCGGCCTCATAAGCCTTACAGGATTCCCAATGCCAGACTATAGGATTACCGGCATACCGATACTAGATGCCTTCCT
AAAGATGGACATCGAGTACATAGTATTGTTTATCAAAAGAATGTGGCTGCCGGCATTCATGCTCGCCTACGGCGGCATAG
GCTTTATAACAAGGATCGTGCGGAATAGCTTCCTCGACGCGTTTAGCGGAGAATACATAAACTTCATGGAAGCCCGTGGC
TTTCCCCGTGGTAGAATCTACATTCACGTGCTCCGAAACGCGCTAACCCCCGTTGTTACAGTTCTGGGCTTAATGTTTGG
CGGGCTCCTGGCGGGCGCGCCGATTACTGAGACCGTCTTTAACCTGCCGGGGCTTGGCACGTACATGATCAGGGCGATAC
ACAACTTCGACTACATAGTGTTGATAGCAGCTGTGCTATTCATAGCACTGATATACGTGACTATAAACTTGATCATAGAC
ATACTTTACGCCATCATAGACCCCAGGGTGAGATACTAG

Upstream 100 bases:

>100_bases
GTGCAGGGAAGCACTAATAGGGGGCAGCCTTATCCCAGAGCCCGGAGCCAACATGTACGAAGTATCATCTCAGTAGCGCG
GGTGAATGGGGGTTAGGGAA

Downstream 100 bases:

>100_bases
AGGGAGGTGAATACACATGCCCGAGTACGTGTACGAGAAGAAGATCCTCGATAGGCTTGCTGACAAGCTGGTTGATGGGC
TTGCAATAGTCATAGACCGT

Product: ABC-type dipeptide/oligopeptide transport system, permease

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MANLRRFLLRRLITFVPTVIGVTFLVYIIAVQIPANPARLWAGGEKADPEVVQRLIEEYHLNDPWYVQYYFFLKKVLSGE
AVSPVTHTNVWDQIMEKLLTVTLPLTLFAFLFIITIGIPLGIIAAIKRDTWIDVVIRAFALIGISTPIFWLAYLLIFVLQ
PRGLISLTGFPMPDYRITGIPILDAFLKMDIEYIVLFIKRMWLPAFMLAYGGIGFITRIVRNSFLDAFSGEYINFMEARG
FPRGRIYIHVLRNALTPVVTVLGLMFGGLLAGAPITETVFNLPGLGTYMIRAIHNFDYIVLIAAVLFIALIYVTINLIID
ILYAIIDPRVRY

Sequences:

>Translated_332_residues
MANLRRFLLRRLITFVPTVIGVTFLVYIIAVQIPANPARLWAGGEKADPEVVQRLIEEYHLNDPWYVQYYFFLKKVLSGE
AVSPVTHTNVWDQIMEKLLTVTLPLTLFAFLFIITIGIPLGIIAAIKRDTWIDVVIRAFALIGISTPIFWLAYLLIFVLQ
PRGLISLTGFPMPDYRITGIPILDAFLKMDIEYIVLFIKRMWLPAFMLAYGGIGFITRIVRNSFLDAFSGEYINFMEARG
FPRGRIYIHVLRNALTPVVTVLGLMFGGLLAGAPITETVFNLPGLGTYMIRAIHNFDYIVLIAAVLFIALIYVTINLIID
ILYAIIDPRVRY
>Mature_331_residues
ANLRRFLLRRLITFVPTVIGVTFLVYIIAVQIPANPARLWAGGEKADPEVVQRLIEEYHLNDPWYVQYYFFLKKVLSGEA
VSPVTHTNVWDQIMEKLLTVTLPLTLFAFLFIITIGIPLGIIAAIKRDTWIDVVIRAFALIGISTPIFWLAYLLIFVLQP
RGLISLTGFPMPDYRITGIPILDAFLKMDIEYIVLFIKRMWLPAFMLAYGGIGFITRIVRNSFLDAFSGEYINFMEARGF
PRGRIYIHVLRNALTPVVTVLGLMFGGLLAGAPITETVFNLPGLGTYMIRAIHNFDYIVLIAAVLFIALIYVTINLIIDI
LYAIIDPRVRY

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=35.7142857142857, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1787053, Length=330, Percent_Identity=32.7272727272727, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787761, Length=329, Percent_Identity=34.6504559270517, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787497, Length=329, Percent_Identity=27.9635258358663, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789888, Length=330, Percent_Identity=30.3030303030303, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=35.2941176470588, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788504, Length=303, Percent_Identity=28.0528052805281, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37724; Mature: 37593

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50928 ABC_TM1 ; PS00214 FABP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLRRFLLRRLITFVPTVIGVTFLVYIIAVQIPANPARLWAGGEKADPEVVQRLIEEYH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHC
LNDPWYVQYYFFLKKVLSGEAVSPVTHTNVWDQIMEKLLTVTLPLTLFAFLFIITIGIPL
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIIAAIKRDTWIDVVIRAFALIGISTPIFWLAYLLIFVLQPRGLISLTGFPMPDYRITGI
HHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCEECCH
PILDAFLKMDIEYIVLFIKRMWLPAFMLAYGGIGFITRIVRNSFLDAFSGEYINFMEARG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHCC
FPRGRIYIHVLRNALTPVVTVLGLMFGGLLAGAPITETVFNLPGLGTYMIRAIHNFDYIV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCCHHHH
LIAAVLFIALIYVTINLIIDILYAIIDPRVRY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ANLRRFLLRRLITFVPTVIGVTFLVYIIAVQIPANPARLWAGGEKADPEVVQRLIEEYH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHC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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]