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The map label for this gene is appC [H]

Identifier: 124027491

GI number: 124027491

Start: 578321

End: 579532

Strand: Reverse

Name: appC [H]

Synonym: Hbut_0607

Alternate gene names: 124027491

Gene position: 579532-578321 (Counterclockwise)

Preceding gene: 124027492

Following gene: 124027490

Centisome position: 34.76

GC content: 52.06

Gene sequence:

>1212_bases
ATGCCCGAGTACGTGTACGAGAAGAAGATCCTCGATAGGCTTGCTGACAAGCTGGTTGATGGGCTTGCAATAGTCATAGA
CCGTGTTAGGCCTGGCTGGAAGCTGAAGAACCAGGGCCGGCTCGAGGAGTGGAAGCTAATGCTATACACGCTCAACCGTT
CACCTCTAGGCCTTACTGGCCTCGTGCTGGTAGCTGCATTTGTAATACTTGCAATCATTGGGCCATACATCGCCCCGGTA
AGCTACGATACCCAGTTTATCTTCTGCGAGAAGACCAAGAAGCCTGGCGAGTTTGAATCCAAGCTAGCGCCTCCAGGTAC
AACTATCGAGATACGAAATAGCACATACTGTCGTAGGGTAGGGCTGGAGCCCGGCAACTTCACATTCATACTTGGCTCGG
ATAACTTTGGTAGAGACCTTTACAGCAGGATACTCTATGGTGCACGTACAAGTCTTGTCGTCGCAATACTTGTAGTTAGC
GTAGGCGCAACCATAGGTATACTGTTGGGGCTCGTTGCAGGCTACTATGGCGGCGCTGTTGACGAGGTTATAATGAGGAT
TACCGATATATTCCTCGCGTTCCCAGGGCTAATACTAGCTATAGCCTTCTCAGCAACGCTACCCTACGCGCTGCAAGGGG
TCTTCGAGCAGTACCCGAACATTGCTACCATCTTACGCTACCTATTCGCTGTCAAGCCTGAGCATGAGCCCGCACTTGCC
AGCCTGGCATCTGTAATAATTGCACTCTGGATGGTATGGTGGCCATCCTATACGAGGCTCGTGCGCGGCATGGTGCTTAG
TGTAAGGGAGAACACTTACGTTGAGGCTGCAAGGGCTCTAGGCGTCTCCACTCTAGGCATAATGTTCCGCCACATATTGC
CAAACATGATTGGCCCTGTACTAGTATACGTAACGATGGACATGGGTGGTGTTATACTCACGGAGGCTGGACTAAGCTAC
CTAGGCCTAGGTGTTGTCCCGCCGCTAGCTGACTGGGGCAGGATAATATTCGACGGAGCCCAGTACTTCCCCCGAGCTTG
GTGGCTAATATTCTGGCCAGGCTTAATGATATTCCTCACAGTCTTCGGCTTCAACTTGCTCGGCGACGCTCTGAGAGACA
TACTAGACCCTAGGACTAGGAGGAGCATAGAGTTCAAGGTGAAGAAGGTGGTTGAGGCTGAGGAAGAGGCAGCTGGTGGG
GGTGGCGAGTGA

Upstream 100 bases:

>100_bases
CTATTCATAGCACTGATATACGTGACTATAAACTTGATCATAGACATACTTTACGCCATCATAGACCCCAGGGTGAGATA
CTAGAGGGAGGTGAATACAC

Downstream 100 bases:

>100_bases
AATGGGTGGCGGTATGCTTCGCTGCCGGGACCCCATAGTCGAGGTTCGCGACCTGTACGTCAACTTCTACACGTATGCCG
GCGTAGTCAAGGCGATCTAC

Product: ABC-type dipeptide/oligopeptide/nickel transport system, permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MPEYVYEKKILDRLADKLVDGLAIVIDRVRPGWKLKNQGRLEEWKLMLYTLNRSPLGLTGLVLVAAFVILAIIGPYIAPV
SYDTQFIFCEKTKKPGEFESKLAPPGTTIEIRNSTYCRRVGLEPGNFTFILGSDNFGRDLYSRILYGARTSLVVAILVVS
VGATIGILLGLVAGYYGGAVDEVIMRITDIFLAFPGLILAIAFSATLPYALQGVFEQYPNIATILRYLFAVKPEHEPALA
SLASVIIALWMVWWPSYTRLVRGMVLSVRENTYVEAARALGVSTLGIMFRHILPNMIGPVLVYVTMDMGGVILTEAGLSY
LGLGVVPPLADWGRIIFDGAQYFPRAWWLIFWPGLMIFLTVFGFNLLGDALRDILDPRTRRSIEFKVKKVVEAEEEAAGG
GGE

Sequences:

>Translated_403_residues
MPEYVYEKKILDRLADKLVDGLAIVIDRVRPGWKLKNQGRLEEWKLMLYTLNRSPLGLTGLVLVAAFVILAIIGPYIAPV
SYDTQFIFCEKTKKPGEFESKLAPPGTTIEIRNSTYCRRVGLEPGNFTFILGSDNFGRDLYSRILYGARTSLVVAILVVS
VGATIGILLGLVAGYYGGAVDEVIMRITDIFLAFPGLILAIAFSATLPYALQGVFEQYPNIATILRYLFAVKPEHEPALA
SLASVIIALWMVWWPSYTRLVRGMVLSVRENTYVEAARALGVSTLGIMFRHILPNMIGPVLVYVTMDMGGVILTEAGLSY
LGLGVVPPLADWGRIIFDGAQYFPRAWWLIFWPGLMIFLTVFGFNLLGDALRDILDPRTRRSIEFKVKKVVEAEEEAAGG
GGE
>Mature_402_residues
PEYVYEKKILDRLADKLVDGLAIVIDRVRPGWKLKNQGRLEEWKLMLYTLNRSPLGLTGLVLVAAFVILAIIGPYIAPVS
YDTQFIFCEKTKKPGEFESKLAPPGTTIEIRNSTYCRRVGLEPGNFTFILGSDNFGRDLYSRILYGARTSLVVAILVVSV
GATIGILLGLVAGYYGGAVDEVIMRITDIFLAFPGLILAIAFSATLPYALQGVFEQYPNIATILRYLFAVKPEHEPALAS
LASVIIALWMVWWPSYTRLVRGMVLSVRENTYVEAARALGVSTLGIMFRHILPNMIGPVLVYVTMDMGGVILTEAGLSYL
GLGVVPPLADWGRIIFDGAQYFPRAWWLIFWPGLMIFLTVFGFNLLGDALRDILDPRTRRSIEFKVKKVVEAEEEAAGGG
GE

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=354, Percent_Identity=33.0508474576271, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787760, Length=351, Percent_Identity=32.7635327635328, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789964, Length=284, Percent_Identity=36.6197183098592, Blast_Score=161, Evalue=9e-41,
Organism=Escherichia coli, GI1789889, Length=248, Percent_Identity=35.8870967741936, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787498, Length=349, Percent_Identity=33.5243553008596, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787549, Length=316, Percent_Identity=30.6962025316456, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1788505, Length=252, Percent_Identity=29.7619047619048, Blast_Score=92, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 44639; Mature: 44508

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEYVYEKKILDRLADKLVDGLAIVIDRVRPGWKLKNQGRLEEWKLMLYTLNRSPLGLTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEEEEECCCCCCHHH
LVLVAAFVILAIIGPYIAPVSYDTQFIFCEKTKKPGEFESKLAPPGTTIEIRNSTYCRRV
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHCCCCCCCEEEECCCCHHHCC
GLEPGNFTFILGSDNFGRDLYSRILYGARTSLVVAILVVSVGATIGILLGLVAGYYGGAV
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DEVIMRITDIFLAFPGLILAIAFSATLPYALQGVFEQYPNIATILRYLFAVKPEHEPALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHH
SLASVIIALWMVWWPSYTRLVRGMVLSVRENTYVEAARALGVSTLGIMFRHILPNMIGPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVYVTMDMGGVILTEAGLSYLGLGVVPPLADWGRIIFDGAQYFPRAWWLIFWPGLMIFLT
HHHHHHCCCCEEEEHHCHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VFGFNLLGDALRDILDPRTRRSIEFKVKKVVEAEEEAAGGGGE
HHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PEYVYEKKILDRLADKLVDGLAIVIDRVRPGWKLKNQGRLEEWKLMLYTLNRSPLGLTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEEEEECCCCCCHHH
LVLVAAFVILAIIGPYIAPVSYDTQFIFCEKTKKPGEFESKLAPPGTTIEIRNSTYCRRV
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHCCCCCCCEEEECCCCHHHCC
GLEPGNFTFILGSDNFGRDLYSRILYGARTSLVVAILVVSVGATIGILLGLVAGYYGGAV
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DEVIMRITDIFLAFPGLILAIAFSATLPYALQGVFEQYPNIATILRYLFAVKPEHEPALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHH
SLASVIIALWMVWWPSYTRLVRGMVLSVRENTYVEAARALGVSTLGIMFRHILPNMIGPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVYVTMDMGGVILTEAGLSYLGLGVVPPLADWGRIIFDGAQYFPRAWWLIFWPGLMIFLT
HHHHHHCCCCEEEEHHCHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VFGFNLLGDALRDILDPRTRRSIEFKVKKVVEAEEEAAGGGGE
HHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]