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The map label for this gene is aegA [H]

Identifier: 124027382

GI number: 124027382

Start: 475757

End: 476776

Strand: Reverse

Name: aegA [H]

Synonym: Hbut_0495

Alternate gene names: 124027382

Gene position: 476776-475757 (Counterclockwise)

Preceding gene: 124027383

Following gene: 124027381

Centisome position: 28.6

GC content: 52.35

Gene sequence:

>1020_bases
TTGAGATTCATCGTAGGCTGCAAGCCTGGCCAAGCAGAGCCACGCAGCGAGAGGATAGCAATTATCGGTGCTGGCCCGGC
CGGCCTCTACGCTGCCGGTTACCTACGTTGTAGGGGCTTCAACGTTACTGTATTCGATAGGAATCCCGAGCCTGGTGGTT
TCCTAATATTTGGCGTCCTTGAGATACATATTAACAAGGCTAAGGTGCGTGAAGGTATTAAAGAGCTGCATGAGCTAGGC
GTAGAGTTTAGGCAGAACATCACGGTGTGTAGAGATGTCTCGCTCGAGGAGCTAATAAACAACTATGACGCGGTACTGAT
AGCGACTGGCACCTGGGAGAGTGCCAGACTAAACATCCCGGGCGCAAATCTTGAAGGCATATATCCGGCTATGGAGTGGA
TCGTAGACTACCACATGTGGAAGTACGGGTATAAGAGTGAGAAGCCGCCGATAGGCGAAAGGGTCGTTGTTATAGGTGGC
GGCCTCACAGCTGTAGACGCTGTTCATGTCTCAAAGTGGCTTGGAGCTAAGGAGGTCTACATGGTGTATAGACGTATACG
CCAATACGCTCCCGCGGGTGAAAGGGGGTTCAGGGAAGCCGAAGAAGCTGGTGCGAAGATCATTGAGCTAGCCTCACCGG
TAGAGTACATACCAGATCCAAGTGGTAAGCGTGTTGCCGCAGTCAAGTTTGAAAGGATGAAGCTTGTTGAGCAACCCGGC
TCCAAGAGGCCCAAGCCCGTGGGTACTGGTGAGTATTTCACAATAGAGGCGGACCTCGTCCTTGAAGCCATAGGGCTCAA
ACCAACACCACCATGCAATGTAGAGCAGCTGGGCATAAAGCTTAGGCCGGACGGCACAATAGATGTTGACGAGTACAAGA
GGACCACTAGAGAGCCAGTGTTCGCTGCTGGCGACGTTGAACACGGTGCTAGTCTGATAGGCATTGCGATGAAGGGAGGC
CTAGACGCTGCCAAAGCGATAGAGAAGTATCTCAACAGGGAGATAGGCTGGAGGAGTTAG

Upstream 100 bases:

>100_bases
GTATAGCTATTTGTACATTTGTACTATTCTACCGATATTCCACCCGTATACGAATTCTTCTTAAACGATTCACCATATAC
AATGCATACGGTGCCCTACG

Downstream 100 bases:

>100_bases
TCCCGCTCCTCACAATCCAATCTCCGGCATAGCCCGTAGTTCTATTTTTAAAGAATTAGGGTGATTCTTCCAGATACCTG
GTGCTAGACCCCTTGTCGAC

Product: NADPH glutamate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MRFIVGCKPGQAEPRSERIAIIGAGPAGLYAAGYLRCRGFNVTVFDRNPEPGGFLIFGVLEIHINKAKVREGIKELHELG
VEFRQNITVCRDVSLEELINNYDAVLIATGTWESARLNIPGANLEGIYPAMEWIVDYHMWKYGYKSEKPPIGERVVVIGG
GLTAVDAVHVSKWLGAKEVYMVYRRIRQYAPAGERGFREAEEAGAKIIELASPVEYIPDPSGKRVAAVKFERMKLVEQPG
SKRPKPVGTGEYFTIEADLVLEAIGLKPTPPCNVEQLGIKLRPDGTIDVDEYKRTTREPVFAAGDVEHGASLIGIAMKGG
LDAAKAIEKYLNREIGWRS

Sequences:

>Translated_339_residues
MRFIVGCKPGQAEPRSERIAIIGAGPAGLYAAGYLRCRGFNVTVFDRNPEPGGFLIFGVLEIHINKAKVREGIKELHELG
VEFRQNITVCRDVSLEELINNYDAVLIATGTWESARLNIPGANLEGIYPAMEWIVDYHMWKYGYKSEKPPIGERVVVIGG
GLTAVDAVHVSKWLGAKEVYMVYRRIRQYAPAGERGFREAEEAGAKIIELASPVEYIPDPSGKRVAAVKFERMKLVEQPG
SKRPKPVGTGEYFTIEADLVLEAIGLKPTPPCNVEQLGIKLRPDGTIDVDEYKRTTREPVFAAGDVEHGASLIGIAMKGG
LDAAKAIEKYLNREIGWRS
>Mature_339_residues
MRFIVGCKPGQAEPRSERIAIIGAGPAGLYAAGYLRCRGFNVTVFDRNPEPGGFLIFGVLEIHINKAKVREGIKELHELG
VEFRQNITVCRDVSLEELINNYDAVLIATGTWESARLNIPGANLEGIYPAMEWIVDYHMWKYGYKSEKPPIGERVVVIGG
GLTAVDAVHVSKWLGAKEVYMVYRRIRQYAPAGERGFREAEEAGAKIIELASPVEYIPDPSGKRVAAVKFERMKLVEQPG
SKRPKPVGTGEYFTIEADLVLEAIGLKPTPPCNVEQLGIKLRPDGTIDVDEYKRTTREPVFAAGDVEHGASLIGIAMKGG
LDAAKAIEKYLNREIGWRS

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=166, Percent_Identity=27.710843373494, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI111118983, Length=166, Percent_Identity=27.710843373494, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788811, Length=327, Percent_Identity=35.474006116208, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI87082180, Length=323, Percent_Identity=34.3653250773994, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789606, Length=342, Percent_Identity=32.4561403508772, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1788468, Length=316, Percent_Identity=30.6962025316456, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789243, Length=318, Percent_Identity=30.188679245283, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17570289, Length=360, Percent_Identity=28.8888888888889, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17543860, Length=159, Percent_Identity=32.7044025157233, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320030, Length=345, Percent_Identity=28.1159420289855, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24665547, Length=348, Percent_Identity=31.8965517241379, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24665543, Length=348, Percent_Identity=31.8965517241379, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574881, Length=348, Percent_Identity=31.8965517241379, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24665539, Length=348, Percent_Identity=31.8965517241379, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI17137178, Length=164, Percent_Identity=31.0975609756098, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006 [H]

Pfam domain/function: PF00037 Fer4; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 37410; Mature: 37410

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFIVGCKPGQAEPRSERIAIIGAGPAGLYAAGYLRCRGFNVTVFDRNPEPGGFLIFGVL
CEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHEEEEECCEEEEEECCCCCCCEEEEEEE
EIHINKAKVREGIKELHELGVEFRQNITVCRDVSLEELINNYDAVLIATGTWESARLNIP
EEEECHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHCCCCEEEEEECCCCCCEEECC
GANLEGIYPAMEWIVDYHMWKYGYKSEKPPIGERVVVIGGGLTAVDAVHVSKWLGAKEVY
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCHHHHH
MVYRRIRQYAPAGERGFREAEEAGAKIIELASPVEYIPDPSGKRVAAVKFERMKLVEQPG
HHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCHHHCCCCCCCEEEEEEHHHHHHHHCCC
SKRPKPVGTGEYFTIEADLVLEAIGLKPTPPCNVEQLGIKLRPDGTIDVDEYKRTTREPV
CCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCHHHCCEEECCCCCEEHHHHHHHHCCCE
FAAGDVEHGASLIGIAMKGGLDAAKAIEKYLNREIGWRS
EEECCHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRFIVGCKPGQAEPRSERIAIIGAGPAGLYAAGYLRCRGFNVTVFDRNPEPGGFLIFGVL
CEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHEEEEECCEEEEEECCCCCCCEEEEEEE
EIHINKAKVREGIKELHELGVEFRQNITVCRDVSLEELINNYDAVLIATGTWESARLNIP
EEEECHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHCCCCEEEEEECCCCCCEEECC
GANLEGIYPAMEWIVDYHMWKYGYKSEKPPIGERVVVIGGGLTAVDAVHVSKWLGAKEVY
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCHHHHH
MVYRRIRQYAPAGERGFREAEEAGAKIIELASPVEYIPDPSGKRVAAVKFERMKLVEQPG
HHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCHHHCCCCCCCEEEEEEHHHHHHHHCCC
SKRPKPVGTGEYFTIEADLVLEAIGLKPTPPCNVEQLGIKLRPDGTIDVDEYKRTTREPV
CCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCHHHCCEEECCCCCEEHHHHHHHHCCCE
FAAGDVEHGASLIGIAMKGGLDAAKAIEKYLNREIGWRS
EEECCHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955321; 9205837; 9278503 [H]