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The map label for this gene is rsmB [H]

Identifier: 124027346

GI number: 124027346

Start: 438549

End: 439886

Strand: Reverse

Name: rsmB [H]

Synonym: Hbut_0455

Alternate gene names: 124027346

Gene position: 439886-438549 (Counterclockwise)

Preceding gene: 124027347

Following gene: 124027345

Centisome position: 26.39

GC content: 52.09

Gene sequence:

>1338_bases
ATGCCGCTAAGGGTTACGGTGAGGATAGCGAGAGCCTATCTTGAAGCCCTAGTGCTTGGCGACAGGATTAAGCCATTTCA
AGCTGCAAAGAGGAGGGTTTTTGCACGCTACCACATACTGGGCACAAAGTACGACCGTGTATTTACAGCGATAACCTATA
GGATGTTTAGGCTACTCGGCATCGTGGATAAGATAATAGCTGAACGCATAGGCAGAATTGACTATCCCACACCAGTCATG
CAGGCTCTACGACTAGCAGTCATGGTCTCCCAATTCGATACGGTGGGCGACAGAGTGTTTAGTGAGTCTCTCATAGAAAA
CCTTGCGAGGATTATTGAGTCAGAGTACCCGGGGATGGGGGAACTGGTAGTAAGGCTCTACAAGAGCCTAGAGAAGGAGC
CCTGGAGTCCATCCACGAAGCTCGAAGAGCTAGAGTATCGACTCCTTCTTCCCCGGATACTAGTAGAGGAGCTTCAGAAG
CTGTTACCTCCCGGTGAGGTTGAAGAGTTTGCAAAAGCTGTAAACACGGATAGGCCCACGTTAGGCTTTCGCGTCAATAG
GTTAAAGGCCAGTGTTGAGGAGATTATTGAGGAGCTTCAGTATGCAGGAGTAGATGCGTGGCCTAGTACACGCATACCAT
ACCACGTATCCTACAAGGGCTCCCTCAACTATAGCCGGTTTAAACCCCTACTTGAGGGCAAGGTCGTGCCGCAGGACGAG
GCTAGTGCTGCTGCTGGCTACCTACTAGGTGCAAAGCCCGGCGAGCTAATAGTCGATATGTGTGCTGCTCCTGGAGGCAA
GACAACACATCTAGCCGAGCTATCAGCGCTCGGAGCGAGGATAGTAGCGATAGACGTCTTTATAGATAGGCTTGAGCGGC
TAATAGAGCTGGCAACGCGCACTGGCACGTGGCCTTCAATATACCCAGTTAGAAGTGATGCGATCTTTGCATCCCGCTAT
GTCAGGGACAGAGTTGATAGAGTTCTCCTTGACCCACCTTGCACTAGTACTGGTGCTTTGGCAAAGCATCCCGAGGCCAG
GTGGAGGCTCACAAGGGAAGCCATAGTAAGGCATGTGGGGCTCCAGCGCCGCTTACTACTTGAAGCTGTTAAGCTGCTAA
AGCCTGGCGGCCTCCTCCTTTATACGGTTTGCAGCGTTCTACCCGAGGAGGGCGAGGAGAACATAAAATGGTTACTAGAG
ACGGTGAAGGGTATCGAGATTGTGCCCCTTACCGGCCCATATGATCCATCCCCGCTTCTCCCAGGCACTATGAGGGCTTG
GCCCCACCGACACGGGACAACAGGGTTCTTCTATGCGCTGCTAGAAAGGAAGGAGTGA

Upstream 100 bases:

>100_bases
TATCCGCGAGGCTGTTGTCCGGGGGCTCTACACTCCCTATAACATGGCGGTATACCTTGCTGTTAAAGGGCTGGAAGAAG
TATTAAGGGGCTAGCTTGGG

Downstream 100 bases:

>100_bases
TGCTGAAGCGATAATTACCCGTAGTTCCCCATGTTCCAACCTGGTGTTTTAGTGTGGGGGTTTGCAGAGTAGCTGTTGGC
TCAACAAACCCGGTGAAAGT

Product: methyltransferase B - rRNA small subunit

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MPLRVTVRIARAYLEALVLGDRIKPFQAAKRRVFARYHILGTKYDRVFTAITYRMFRLLGIVDKIIAERIGRIDYPTPVM
QALRLAVMVSQFDTVGDRVFSESLIENLARIIESEYPGMGELVVRLYKSLEKEPWSPSTKLEELEYRLLLPRILVEELQK
LLPPGEVEEFAKAVNTDRPTLGFRVNRLKASVEEIIEELQYAGVDAWPSTRIPYHVSYKGSLNYSRFKPLLEGKVVPQDE
ASAAAGYLLGAKPGELIVDMCAAPGGKTTHLAELSALGARIVAIDVFIDRLERLIELATRTGTWPSIYPVRSDAIFASRY
VRDRVDRVLLDPPCTSTGALAKHPEARWRLTREAIVRHVGLQRRLLLEAVKLLKPGGLLLYTVCSVLPEEGEENIKWLLE
TVKGIEIVPLTGPYDPSPLLPGTMRAWPHRHGTTGFFYALLERKE

Sequences:

>Translated_445_residues
MPLRVTVRIARAYLEALVLGDRIKPFQAAKRRVFARYHILGTKYDRVFTAITYRMFRLLGIVDKIIAERIGRIDYPTPVM
QALRLAVMVSQFDTVGDRVFSESLIENLARIIESEYPGMGELVVRLYKSLEKEPWSPSTKLEELEYRLLLPRILVEELQK
LLPPGEVEEFAKAVNTDRPTLGFRVNRLKASVEEIIEELQYAGVDAWPSTRIPYHVSYKGSLNYSRFKPLLEGKVVPQDE
ASAAAGYLLGAKPGELIVDMCAAPGGKTTHLAELSALGARIVAIDVFIDRLERLIELATRTGTWPSIYPVRSDAIFASRY
VRDRVDRVLLDPPCTSTGALAKHPEARWRLTREAIVRHVGLQRRLLLEAVKLLKPGGLLLYTVCSVLPEEGEENIKWLLE
TVKGIEIVPLTGPYDPSPLLPGTMRAWPHRHGTTGFFYALLERKE
>Mature_444_residues
PLRVTVRIARAYLEALVLGDRIKPFQAAKRRVFARYHILGTKYDRVFTAITYRMFRLLGIVDKIIAERIGRIDYPTPVMQ
ALRLAVMVSQFDTVGDRVFSESLIENLARIIESEYPGMGELVVRLYKSLEKEPWSPSTKLEELEYRLLLPRILVEELQKL
LPPGEVEEFAKAVNTDRPTLGFRVNRLKASVEEIIEELQYAGVDAWPSTRIPYHVSYKGSLNYSRFKPLLEGKVVPQDEA
SAAAGYLLGAKPGELIVDMCAAPGGKTTHLAELSALGARIVAIDVFIDRLERLIELATRTGTWPSIYPVRSDAIFASRYV
RDRVDRVLLDPPCTSTGALAKHPEARWRLTREAIVRHVGLQRRLLLEAVKLLKPGGLLLYTVCSVLPEEGEENIKWLLET
VKGIEIVPLTGPYDPSPLLPGTMRAWPHRHGTTGFFYALLERKE

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=311, Percent_Identity=30.2250803858521, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI76150623, Length=311, Percent_Identity=30.2250803858521, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI32698918, Length=183, Percent_Identity=31.1475409836066, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI8922322, Length=227, Percent_Identity=31.7180616740088, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI270288818, Length=227, Percent_Identity=31.7180616740088, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI23199998, Length=227, Percent_Identity=31.7180616740088, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI270288816, Length=227, Percent_Identity=31.7180616740088, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI39995082, Length=377, Percent_Identity=25.4641909814324, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI301336155, Length=354, Percent_Identity=26.5536723163842, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI2367212, Length=410, Percent_Identity=28.0487804878049, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI87081985, Length=324, Percent_Identity=27.4691358024691, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17536757, Length=310, Percent_Identity=30.3225806451613, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71998419, Length=226, Percent_Identity=28.7610619469027, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534021, Length=223, Percent_Identity=29.1479820627803, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25143471, Length=302, Percent_Identity=27.1523178807947, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=361, Percent_Identity=27.9778393351801, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI22024126, Length=310, Percent_Identity=30.6451612903226, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24668781, Length=233, Percent_Identity=30.0429184549356, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21356513, Length=223, Percent_Identity=30.4932735426009, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21355201, Length=212, Percent_Identity=29.2452830188679, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356579, Length=268, Percent_Identity=23.8805970149254, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 50266; Mature: 50135

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLRVTVRIARAYLEALVLGDRIKPFQAAKRRVFARYHILGTKYDRVFTAITYRMFRLLG
CCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IVDKIIAERIGRIDYPTPVMQALRLAVMVSQFDTVGDRVFSESLIENLARIIESEYPGMG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELVVRLYKSLEKEPWSPSTKLEELEYRLLLPRILVEELQKLLPPGEVEEFAKAVNTDRPT
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCC
LGFRVNRLKASVEEIIEELQYAGVDAWPSTRIPYHVSYKGSLNYSRFKPLLEGKVVPQDE
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCC
ASAAAGYLLGAKPGELIVDMCAAPGGKTTHLAELSALGARIVAIDVFIDRLERLIELATR
HHHHHHHEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGTWPSIYPVRSDAIFASRYVRDRVDRVLLDPPCTSTGALAKHPEARWRLTREAIVRHVG
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHH
LQRRLLLEAVKLLKPGGLLLYTVCSVLPEEGEENIKWLLETVKGIEIVPLTGPYDPSPLL
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCC
PGTMRAWPHRHGTTGFFYALLERKE
CCCHHHCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
PLRVTVRIARAYLEALVLGDRIKPFQAAKRRVFARYHILGTKYDRVFTAITYRMFRLLG
CEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IVDKIIAERIGRIDYPTPVMQALRLAVMVSQFDTVGDRVFSESLIENLARIIESEYPGMG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELVVRLYKSLEKEPWSPSTKLEELEYRLLLPRILVEELQKLLPPGEVEEFAKAVNTDRPT
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCC
LGFRVNRLKASVEEIIEELQYAGVDAWPSTRIPYHVSYKGSLNYSRFKPLLEGKVVPQDE
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCC
ASAAAGYLLGAKPGELIVDMCAAPGGKTTHLAELSALGARIVAIDVFIDRLERLIELATR
HHHHHHHEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TGTWPSIYPVRSDAIFASRYVRDRVDRVLLDPPCTSTGALAKHPEARWRLTREAIVRHVG
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHH
LQRRLLLEAVKLLKPGGLLLYTVCSVLPEEGEENIKWLLETVKGIEIVPLTGPYDPSPLL
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCC
PGTMRAWPHRHGTTGFFYALLERKE
CCCHHHCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA