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The map label for this gene is sucC [H]

Identifier: 124027100

GI number: 124027100

Start: 183750

End: 184883

Strand: Reverse

Name: sucC [H]

Synonym: Hbut_0203

Alternate gene names: 124027100

Gene position: 184883-183750 (Counterclockwise)

Preceding gene: 124027101

Following gene: 124027099

Centisome position: 11.09

GC content: 56.44

Gene sequence:

>1134_bases
TTGAAGCTATTCGAGTTCGAGGCAAAGGAGATTTTGAGGAAGTATGGTGCCGATGTACCGCCAGGCGTCGTTATTGCCCG
GGGCGAGGATGCCCGGGAGAAGATCCTCGAGGCGGGGCTGGAGCCGCCTCTCATGGTTAAGAGCCAGGTTCTCGTAGCTG
GCCGCGGCAAGGCTGGCGGCATAAGGAGGGCCAATTCCATCGATGAGGCTGTTAGGCTGGTTGGGGAGCTGTTTGAGACC
CCTATCAAGGGGCTTAAGCCACGCTACATACTGGTTGAGAAGGCTGTTGAGCATGAGGCGGAGCTCTACACTGCTATCAC
GCTTGATCGTAGCAAGAGGAGGCCTGTAGTCCTGGTATCCAGGTACGGCGGCATGGATATTGAGGAGATTGCGCGGGAGA
AACCGGAGAGCATCATAAGAATGCACGTTGACCCCGTGCTAGGCCTGCGGGGCTACCACGCTAGAAAGCTGGGCAAGGCT
ATAGGCCTCAGTGGCAGGGCACTGACGAGCTTTGCAGCCTTCCTGCAGGCAATGTACCAGGTATTCGTGGATTATGACGC
GGAACTCGTGGAGTCTAACCCGCTGGGCCTCGTCGGCGACAAGGTGATCCCTCTCGACGCAAGGATAATTGTCGACGATA
ATGCGCTCTACAGGCACCAGGAGCTAGCCAAGGACATCGAAGAGACCGGCGAGTATAGCGAGTGGGAGATAAAGGCTAGG
AGGCAGGGCCTAGCCTTTGTAGAGCTTGACGGCGACATAGGAATCATAGGGAACGGTGCAGGCCTAACAATGGCAACCAT
GGACCTCGTATACGAGCATGGTGGCAGACCGGCAAACTTCCTCGACATAGGCGGTGGCGCAAGCGCCGAGGCCGTGAAGA
GGGCTGTGTTGTTCCTCTTCGAGTACCCCAAGGCAAGAAAGATATTCATAAACATCTTCGGCGGAATAACCCGCTGCGAC
GAGGTTGCTAGGGGCGTTGTCGAAGCTATCAAGGAGGCTGGAGGACTGAGGAAGCCCATTGTGATAAGGCTAACGGGCAC
CAACGAGGAGGAGGGCCGCCGAATACTCAGGGAACACGGTATAGAAGCTTTTGACGACCCATTCGAGGCTGTCAAGCGCA
TCATATCCCTCTAG

Upstream 100 bases:

>100_bases
CTCCATAAATACCAGCGAACCTGGACTAGGACATAACGGTGCTGAGGATCCAAAAGCGACCATAGCCTTCTCTTGGGTAG
TGTGGGGTGTTGGCTGGGCC

Downstream 100 bases:

>100_bases
GTGTACGTGAACCACAACCTGGGGGGTGGGTTGTCGTGGCGATACTCGCGGATGAGAACACTAGGGTTATCGTGCAGGGT
ATAACTGGGCGCGAGGGCAG

Product: succinyl-CoA synthetase beta chain

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MKLFEFEAKEILRKYGADVPPGVVIARGEDAREKILEAGLEPPLMVKSQVLVAGRGKAGGIRRANSIDEAVRLVGELFET
PIKGLKPRYILVEKAVEHEAELYTAITLDRSKRRPVVLVSRYGGMDIEEIAREKPESIIRMHVDPVLGLRGYHARKLGKA
IGLSGRALTSFAAFLQAMYQVFVDYDAELVESNPLGLVGDKVIPLDARIIVDDNALYRHQELAKDIEETGEYSEWEIKAR
RQGLAFVELDGDIGIIGNGAGLTMATMDLVYEHGGRPANFLDIGGGASAEAVKRAVLFLFEYPKARKIFINIFGGITRCD
EVARGVVEAIKEAGGLRKPIVIRLTGTNEEEGRRILREHGIEAFDDPFEAVKRIISL

Sequences:

>Translated_377_residues
MKLFEFEAKEILRKYGADVPPGVVIARGEDAREKILEAGLEPPLMVKSQVLVAGRGKAGGIRRANSIDEAVRLVGELFET
PIKGLKPRYILVEKAVEHEAELYTAITLDRSKRRPVVLVSRYGGMDIEEIAREKPESIIRMHVDPVLGLRGYHARKLGKA
IGLSGRALTSFAAFLQAMYQVFVDYDAELVESNPLGLVGDKVIPLDARIIVDDNALYRHQELAKDIEETGEYSEWEIKAR
RQGLAFVELDGDIGIIGNGAGLTMATMDLVYEHGGRPANFLDIGGGASAEAVKRAVLFLFEYPKARKIFINIFGGITRCD
EVARGVVEAIKEAGGLRKPIVIRLTGTNEEEGRRILREHGIEAFDDPFEAVKRIISL
>Mature_377_residues
MKLFEFEAKEILRKYGADVPPGVVIARGEDAREKILEAGLEPPLMVKSQVLVAGRGKAGGIRRANSIDEAVRLVGELFET
PIKGLKPRYILVEKAVEHEAELYTAITLDRSKRRPVVLVSRYGGMDIEEIAREKPESIIRMHVDPVLGLRGYHARKLGKA
IGLSGRALTSFAAFLQAMYQVFVDYDAELVESNPLGLVGDKVIPLDARIIVDDNALYRHQELAKDIEETGEYSEWEIKAR
RQGLAFVELDGDIGIIGNGAGLTMATMDLVYEHGGRPANFLDIGGGASAEAVKRAVLFLFEYPKARKIFINIFGGITRCD
EVARGVVEAIKEAGGLRKPIVIRLTGTNEEEGRRILREHGIEAFDDPFEAVKRIISL

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=394, Percent_Identity=35.2791878172589, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI157779135, Length=378, Percent_Identity=34.1269841269841, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI294862256, Length=364, Percent_Identity=34.0659340659341, Blast_Score=199, Evalue=3e-51,
Organism=Escherichia coli, GI1786948, Length=372, Percent_Identity=38.1720430107527, Blast_Score=231, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI17539378, Length=379, Percent_Identity=35.6200527704486, Blast_Score=231, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17567829, Length=395, Percent_Identity=35.1898734177215, Blast_Score=220, Evalue=7e-58,
Organism=Saccharomyces cerevisiae, GI6321683, Length=397, Percent_Identity=35.5163727959698, Blast_Score=231, Evalue=1e-61,
Organism=Drosophila melanogaster, GI21356231, Length=378, Percent_Identity=34.9206349206349, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI281361397, Length=335, Percent_Identity=38.5074626865672, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI281361395, Length=335, Percent_Identity=38.5074626865672, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI161078106, Length=336, Percent_Identity=38.3928571428571, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24645208, Length=336, Percent_Identity=38.3928571428571, Blast_Score=208, Evalue=5e-54,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41633; Mature: 41633

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFEFEAKEILRKYGADVPPGVVIARGEDAREKILEAGLEPPLMVKSQVLVAGRGKAGG
CCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCCEECCEEEEEECCCCCC
IRRANSIDEAVRLVGELFETPIKGLKPRYILVEKAVEHEAELYTAITLDRSKRRPVVLVS
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHEEEEEEECCCCCCCEEEEE
RYGGMDIEEIAREKPESIIRMHVDPVLGLRGYHARKLGKAIGLSGRALTSFAAFLQAMYQ
CCCCCCHHHHHHHCHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VFVDYDAELVESNPLGLVGDKVIPLDARIIVDDNALYRHQELAKDIEETGEYSEWEIKAR
HHHCCCHHHHCCCCCCEECCEEECCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEHHHH
RQGLAFVELDGDIGIIGNGAGLTMATMDLVYEHGGRPANFLDIGGGASAEAVKRAVLFLF
HCCEEEEEECCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHH
EYPKARKIFINIFGGITRCDEVARGVVEAIKEAGGLRKPIVIRLTGTNEEEGRRILREHG
CCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCC
IEAFDDPFEAVKRIISL
CCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKLFEFEAKEILRKYGADVPPGVVIARGEDAREKILEAGLEPPLMVKSQVLVAGRGKAGG
CCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCCEECCEEEEEECCCCCC
IRRANSIDEAVRLVGELFETPIKGLKPRYILVEKAVEHEAELYTAITLDRSKRRPVVLVS
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHEEEEEEECCCCCCCEEEEE
RYGGMDIEEIAREKPESIIRMHVDPVLGLRGYHARKLGKAIGLSGRALTSFAAFLQAMYQ
CCCCCCHHHHHHHCHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VFVDYDAELVESNPLGLVGDKVIPLDARIIVDDNALYRHQELAKDIEETGEYSEWEIKAR
HHHCCCHHHHCCCCCCEECCEEECCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEHHHH
RQGLAFVELDGDIGIIGNGAGLTMATMDLVYEHGGRPANFLDIGGGASAEAVKRAVLFLF
HCCEEEEEECCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHH
EYPKARKIFINIFGGITRCDEVARGVVEAIKEAGGLRKPIVIRLTGTNEEEGRRILREHG
CCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCC
IEAFDDPFEAVKRIISL
CCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA