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The map label for this gene is sucD2 [H]

Identifier: 124027099

GI number: 124027099

Start: 182833

End: 183714

Strand: Reverse

Name: sucD2 [H]

Synonym: Hbut_0202

Alternate gene names: 124027099

Gene position: 183714-182833 (Counterclockwise)

Preceding gene: 124027100

Following gene: 124027096

Centisome position: 11.02

GC content: 60.09

Gene sequence:

>882_bases
GTGGCGATACTCGCGGATGAGAACACTAGGGTTATCGTGCAGGGTATAACTGGGCGCGAGGGCAGCTTCCACACAAAGCT
GATGCTAGAGTATGGCACTAAGATAGTCGCGGGTGTAACCCCCGGTAAGGGCGGCATGGAGGTTCACGGGGTACCCGTAT
ACGATACCGTCGAGGAAGCGCTGGAGGAGCACCCGGACGCTAATGCCAGCATAGTGTTTGTACCGGCACGCTTCGCACCC
GACGCAGTATACGAGGCCATCGACGCCGGGTTGAAGCTCGTGGTGGTGATTACCGAGCATATACCCGTCCACGAGACCAT
GAGGTTTGTAAACTACGCCAGGCAGAGGGGCACGGTTATCATAGGCCCCAACTGCCCAGGCATAATCTCCCCCGGCAAGA
CCAAGATAGGTATAATGCCGGGCAGGGTCTTTACGCCAGGCCCCGTAGGCATCGTGTCCCGAAGCGGCACGCTCACCTAC
GAGATAGCCTACGCGCTGACTAGGAGCGGCATAGGCCAGAGCACAGTAGTCGGCATAGGCGGCGACCCCATCGTCGGCTT
GTCCTTCACAGAGGCGATGGAGCTATTCGAGCGGGACCCCGAGACCAAGGTACTGGTGCTGATCGGCGAGATAGGCGGCG
ATATGGAGGAGAGAGCGGCGAGAATGATAGAGGAAGGCCGCTTCACAAAACCCGTAGTAGCCTTCATAGCTGGGCGCACC
GCCCCACCGGGCAAGAGGATGGGCCACGCCGGAGCAATAATCATGATGGGTACCGGCCGCTACGAGGACAAGGTCCGGGC
GCTGGAGAAGGCGGGAGCCAGGGTCGCCCGCTCCCTCAGCGAGATACCACGCCTGGTCAAGGAGGCCCTAGAAAAAGCCT
AA

Upstream 100 bases:

>100_bases
GGGAACACGGTATAGAAGCTTTTGACGACCCATTCGAGGCTGTCAAGCGCATCATATCCCTCTAGGTGTACGTGAACCAC
AACCTGGGGGGTGGGTTGTC

Downstream 100 bases:

>100_bases
CCCAAAATTTTAGCTTGTACACAAACTATTTCATAAATCCTACAGCTTGCACCCCACTCACCATATTAACCGCTGTGTTA
CTACCATTGCCTCGAAGCTG

Product: succinyl-CoA synthetase alpha chain

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha 2; SCS-alpha 2 [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MAILADENTRVIVQGITGREGSFHTKLMLEYGTKIVAGVTPGKGGMEVHGVPVYDTVEEALEEHPDANASIVFVPARFAP
DAVYEAIDAGLKLVVVITEHIPVHETMRFVNYARQRGTVIIGPNCPGIISPGKTKIGIMPGRVFTPGPVGIVSRSGTLTY
EIAYALTRSGIGQSTVVGIGGDPIVGLSFTEAMELFERDPETKVLVLIGEIGGDMEERAARMIEEGRFTKPVVAFIAGRT
APPGKRMGHAGAIIMMGTGRYEDKVRALEKAGARVARSLSEIPRLVKEALEKA

Sequences:

>Translated_293_residues
MAILADENTRVIVQGITGREGSFHTKLMLEYGTKIVAGVTPGKGGMEVHGVPVYDTVEEALEEHPDANASIVFVPARFAP
DAVYEAIDAGLKLVVVITEHIPVHETMRFVNYARQRGTVIIGPNCPGIISPGKTKIGIMPGRVFTPGPVGIVSRSGTLTY
EIAYALTRSGIGQSTVVGIGGDPIVGLSFTEAMELFERDPETKVLVLIGEIGGDMEERAARMIEEGRFTKPVVAFIAGRT
APPGKRMGHAGAIIMMGTGRYEDKVRALEKAGARVARSLSEIPRLVKEALEKA
>Mature_292_residues
AILADENTRVIVQGITGREGSFHTKLMLEYGTKIVAGVTPGKGGMEVHGVPVYDTVEEALEEHPDANASIVFVPARFAPD
AVYEAIDAGLKLVVVITEHIPVHETMRFVNYARQRGTVIIGPNCPGIISPGKTKIGIMPGRVFTPGPVGIVSRSGTLTYE
IAYALTRSGIGQSTVVGIGGDPIVGLSFTEAMELFERDPETKVLVLIGEIGGDMEERAARMIEEGRFTKPVVAFIAGRTA
PPGKRMGHAGAIIMMGTGRYEDKVRALEKAGARVARSLSEIPRLVKEALEKA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=294, Percent_Identity=51.0204081632653, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI38569423, Length=253, Percent_Identity=33.596837944664, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI38569421, Length=253, Percent_Identity=33.596837944664, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1786949, Length=291, Percent_Identity=54.639175257732, Blast_Score=309, Evalue=1e-85,
Organism=Escherichia coli, GI1786513, Length=268, Percent_Identity=24.6268656716418, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786729, Length=191, Percent_Identity=24.6073298429319, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17550194, Length=281, Percent_Identity=52.3131672597865, Blast_Score=260, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=48.6301369863014, Blast_Score=257, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI17557344, Length=254, Percent_Identity=30.3149606299213, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17551266, Length=254, Percent_Identity=29.1338582677165, Blast_Score=120, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6324716, Length=284, Percent_Identity=42.9577464788732, Blast_Score=218, Evalue=9e-58,
Organism=Drosophila melanogaster, GI21356559, Length=275, Percent_Identity=51.2727272727273, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI28574296, Length=280, Percent_Identity=50.7142857142857, Blast_Score=240, Evalue=8e-64,
Organism=Drosophila melanogaster, GI281363477, Length=248, Percent_Identity=31.0483870967742, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281363475, Length=248, Percent_Identity=31.0483870967742, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281363473, Length=248, Percent_Identity=31.0483870967742, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31290; Mature: 31159

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILADENTRVIVQGITGREGSFHTKLMLEYGTKIVAGVTPGKGGMEVHGVPVYDTVEEA
CEEEECCCCEEEEEECCCCCCCCCEEEEEECCCEEEEECCCCCCCEEECCCCCHHHHHHH
LEEHPDANASIVFVPARFAPDAVYEAIDAGLKLVVVITEHIPVHETMRFVNYARQRGTVI
HHHCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEE
IGPNCPGIISPGKTKIGIMPGRVFTPGPVGIVSRSGTLTYEIAYALTRSGIGQSTVVGIG
ECCCCCCCCCCCCEEEEEECCCEECCCCCEEEECCCCEEEEEEEHHHHCCCCCCEEEECC
GDPIVGLSFTEAMELFERDPETKVLVLIGEIGGDMEERAARMIEEGRFTKPVVAFIAGRT
CCCEECCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHCCC
APPGKRMGHAGAIIMMGTGRYEDKVRALEKAGARVARSLSEIPRLVKEALEKA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AILADENTRVIVQGITGREGSFHTKLMLEYGTKIVAGVTPGKGGMEVHGVPVYDTVEEA
EEEECCCCEEEEEECCCCCCCCCEEEEEECCCEEEEECCCCCCCEEECCCCCHHHHHHH
LEEHPDANASIVFVPARFAPDAVYEAIDAGLKLVVVITEHIPVHETMRFVNYARQRGTVI
HHHCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEE
IGPNCPGIISPGKTKIGIMPGRVFTPGPVGIVSRSGTLTYEIAYALTRSGIGQSTVVGIG
ECCCCCCCCCCCCEEEEEECCCEECCCCCEEEECCCCEEEEEEEHHHHCCCCCCEEEECC
GDPIVGLSFTEAMELFERDPETKVLVLIGEIGGDMEERAARMIEEGRFTKPVVAFIAGRT
CCCEECCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHCCC
APPGKRMGHAGAIIMMGTGRYEDKVRALEKAGARVARSLSEIPRLVKEALEKA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]