Click here to switch to the map view.

The map label for this gene is nuoD2 [H]

Identifier: 124027082

GI number: 124027082

Start: 166043

End: 167251

Strand: Direct

Name: nuoD2 [H]

Synonym: Hbut_0185

Alternate gene names: 124027082

Gene position: 166043-167251 (Clockwise)

Preceding gene: 124027080

Following gene: 124027083

Centisome position: 9.96

GC content: 55.17

Gene sequence:

>1209_bases
ATGGCGCAGCTAGAGCTTCCAGGCATGCTCGCCAGGGAGGCTGGCACCCGTGAAGGGTACAGGCTCGTGGAACTCTACAT
AGGCCCCCAGCACCCGGCTTCTGGTCATATGAGGCTTATAGTCTACCTTGACGGCGACCGGATCGTGCGTGTTGATCCCG
ACATAGGCTACGTGCACCGCACAATGGAGAAGCTCTCCGAGATCCGGGAATGGGTTCGTATTGTAGGCCTTGTAGAGAGG
ATGACAATTATAGATTCATGTAATGTGACTCTCCCCTTCGTCGAGGCTGTAGAGAAGCTCCTTGGAATAGAGCCTCCGCC
GCGTGCAAGGTACCTCCGCACGATTCTCTGTGAGGTAAACCGTATCGCGAGCCACCTCTATGGCCTCGGCCTCGGCGGCA
TATTCTTAAACCACTCAACAATGTTCATGTGGGCATTTGGCGATCGTGAGGTCTTCATCCATCTCGCAACACTGCTCACT
GGTGCAAGGCTAACCCATACCTATGCGATACCTGGAGGTGTGCGGCGCGACCTCCCCCAGGTCTTTCGGGATGAGTTTGA
GAAGGCCAAGAGGTATATGCTTCGAAGGCTAAAGGAGTACGAGGATATATTCGTCAAGAACCCAGTTGTGAGGGGAAGGC
TGGAGAACGTTGGTGTCCTACCAAAGCACAAGGCGATAGAGCTAGGCGTTACGGGACCAAACCTCCGTGCCAGCGGCGTG
GTATATGATGCAAGGCTTACAGGCTACGCAGCCTACAGTGAGCTGGACTTTACACCCGTCGTAGGCGAGGCTGGCGACGC
GCTTGAGAGGATACTAGTCCGCGTAGAGGAGATAAAGGTAAGCCTAGACCTCATAGAGCAGGCGCTTAAGAGGCTCCCGG
AGGGCCCGTTCTTCCACGAGCGCTTCGCCAAGATGGTTCCACCGAACATGAAGCACTGGTTTGAAAAGGGCCGCGTCAAG
CTCCCTGGCGGCTATGTGAGGCTACGCCCAGCGCGCGGCGAGATACTGACAAGGGCCGAGATGGGTCACGGCGAGATAAC
ATACTACATTGTGAGCAAGGGTGAGTTTAAGCCCTACAGAGTCCGCATTATAACACCGAGCTTCCGTAATGTCATACTCT
TCATGACCCTCCCCGTCGGCCATACATTGATGGATCTACCCGCAATATATGGTAGCATCGACTACTTCCCACCCGAGTCG
GACAGGTAG

Upstream 100 bases:

>100_bases
GTTTTGAGAACCGGCGGTAAACCATTCGGGGTTGGTTCGCCCGGTTAAGGGCCGGGCTAAACTATAACAGTGGTTAATGT
TGGATCAAAGGGGGCGGGCC

Downstream 100 bases:

>100_bases
CAGGGAATAGAGGTGAGGTAGGCCGTGCTCGTGGACACCCTCGCGTCAGCATTGCATCTCCCCACGTGGCTGGTAAGGGG
GGTACTCGCTCCACTCGTTT

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D 2; NDH-1 subunit D 2 [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MAQLELPGMLAREAGTREGYRLVELYIGPQHPASGHMRLIVYLDGDRIVRVDPDIGYVHRTMEKLSEIREWVRIVGLVER
MTIIDSCNVTLPFVEAVEKLLGIEPPPRARYLRTILCEVNRIASHLYGLGLGGIFLNHSTMFMWAFGDREVFIHLATLLT
GARLTHTYAIPGGVRRDLPQVFRDEFEKAKRYMLRRLKEYEDIFVKNPVVRGRLENVGVLPKHKAIELGVTGPNLRASGV
VYDARLTGYAAYSELDFTPVVGEAGDALERILVRVEEIKVSLDLIEQALKRLPEGPFFHERFAKMVPPNMKHWFEKGRVK
LPGGYVRLRPARGEILTRAEMGHGEITYYIVSKGEFKPYRVRIITPSFRNVILFMTLPVGHTLMDLPAIYGSIDYFPPES
DR

Sequences:

>Translated_402_residues
MAQLELPGMLAREAGTREGYRLVELYIGPQHPASGHMRLIVYLDGDRIVRVDPDIGYVHRTMEKLSEIREWVRIVGLVER
MTIIDSCNVTLPFVEAVEKLLGIEPPPRARYLRTILCEVNRIASHLYGLGLGGIFLNHSTMFMWAFGDREVFIHLATLLT
GARLTHTYAIPGGVRRDLPQVFRDEFEKAKRYMLRRLKEYEDIFVKNPVVRGRLENVGVLPKHKAIELGVTGPNLRASGV
VYDARLTGYAAYSELDFTPVVGEAGDALERILVRVEEIKVSLDLIEQALKRLPEGPFFHERFAKMVPPNMKHWFEKGRVK
LPGGYVRLRPARGEILTRAEMGHGEITYYIVSKGEFKPYRVRIITPSFRNVILFMTLPVGHTLMDLPAIYGSIDYFPPES
DR
>Mature_401_residues
AQLELPGMLAREAGTREGYRLVELYIGPQHPASGHMRLIVYLDGDRIVRVDPDIGYVHRTMEKLSEIREWVRIVGLVERM
TIIDSCNVTLPFVEAVEKLLGIEPPPRARYLRTILCEVNRIASHLYGLGLGGIFLNHSTMFMWAFGDREVFIHLATLLTG
ARLTHTYAIPGGVRRDLPQVFRDEFEKAKRYMLRRLKEYEDIFVKNPVVRGRLENVGVLPKHKAIELGVTGPNLRASGVV
YDARLTGYAAYSELDFTPVVGEAGDALERILVRVEEIKVSLDLIEQALKRLPEGPFFHERFAKMVPPNMKHWFEKGRVKL
PGGYVRLRPARGEILTRAEMGHGEITYYIVSKGEFKPYRVRIITPSFRNVILFMTLPVGHTLMDLPAIYGSIDYFPPESD
R

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=387, Percent_Identity=34.3669250645995, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI260898743, Length=377, Percent_Identity=34.2175066312997, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI145693162, Length=384, Percent_Identity=34.1145833333333, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1789076, Length=381, Percent_Identity=31.496062992126, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1788832, Length=380, Percent_Identity=32.1052631578947, Blast_Score=152, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17555284, Length=387, Percent_Identity=32.0413436692506, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17568379, Length=387, Percent_Identity=31.7829457364341, Blast_Score=197, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24638644, Length=389, Percent_Identity=34.1902313624679, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI221459469, Length=388, Percent_Identity=33.7628865979381, Blast_Score=214, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 45840; Mature: 45709

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLELPGMLAREAGTREGYRLVELYIGPQHPASGHMRLIVYLDGDRIVRVDPDIGYVHR
CCCCCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCEEEEECCCCHHHHH
TMEKLSEIREWVRIVGLVERMTIIDSCNVTLPFVEAVEKLLGIEPPPRARYLRTILCEVN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RIASHLYGLGLGGIFLNHSTMFMWAFGDREVFIHLATLLTGARLTHTYAIPGGVRRDLPQ
HHHHHHHHCCCCCEEEECCEEEEEEECCCHHHHHHHHHHCCCHHEEEEECCCCHHHHHHH
VFRDEFEKAKRYMLRRLKEYEDIFVKNPVVRGRLENVGVLPKHKAIELGVTGPNLRASGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHCCCCCCCCCEEEEECCCCCCEECCE
VYDARLTGYAAYSELDFTPVVGEAGDALERILVRVEEIKVSLDLIEQALKRLPEGPFFHE
EEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
RFAKMVPPNMKHWFEKGRVKLPGGYVRLRPARGEILTRAEMGHGEITYYIVSKGEFKPYR
HHHHHCCCCHHHHHHCCCEECCCCEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCEE
VRIITPSFRNVILFMTLPVGHTLMDLPAIYGSIDYFPPESDR
EEEECCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AQLELPGMLAREAGTREGYRLVELYIGPQHPASGHMRLIVYLDGDRIVRVDPDIGYVHR
CCCCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCEEEEECCCCHHHHH
TMEKLSEIREWVRIVGLVERMTIIDSCNVTLPFVEAVEKLLGIEPPPRARYLRTILCEVN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RIASHLYGLGLGGIFLNHSTMFMWAFGDREVFIHLATLLTGARLTHTYAIPGGVRRDLPQ
HHHHHHHHCCCCCEEEECCEEEEEEECCCHHHHHHHHHHCCCHHEEEEECCCCHHHHHHH
VFRDEFEKAKRYMLRRLKEYEDIFVKNPVVRGRLENVGVLPKHKAIELGVTGPNLRASGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHCCCCCCCCCEEEEECCCCCCEECCE
VYDARLTGYAAYSELDFTPVVGEAGDALERILVRVEEIKVSLDLIEQALKRLPEGPFFHE
EEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
RFAKMVPPNMKHWFEKGRVKLPGGYVRLRPARGEILTRAEMGHGEITYYIVSKGEFKPYR
HHHHHCCCCHHHHHHCCCEECCCCEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCEE
VRIITPSFRNVILFMTLPVGHTLMDLPAIYGSIDYFPPESDR
EEEECCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA