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The map label for this gene is nuoH [H]

Identifier: 124027083

GI number: 124027083

Start: 167506

End: 168294

Strand: Direct

Name: nuoH [H]

Synonym: Hbut_0186

Alternate gene names: 124027083

Gene position: 167506-168294 (Clockwise)

Preceding gene: 124027082

Following gene: 124027084

Centisome position: 10.05

GC content: 54.12

Gene sequence:

>789_bases
ATGTTCCAGGAGATAATAGTGCCCTTTGAGACTGAGAGGCTAGCATTTGCAGCGGCACCCATACTAGCCTTCACGATAGC
AGTGCTGCCTCTAACAGTCATACCTGGCGGTCCAGGAGTCTACGGGTTCACAAGCCCATACAGCATGTTGATAGCGTATG
CACTACTCTCCCTGACAAGCATAGTCATACTCGTCATGGGGTGGGCTGCCTCCAACAAGTTCACACTCATAGGTGCGGGC
CGCGAAATACTCACAGCTATAGCTGGCGAGGTTGTACTTCTAGCCTCGATCCTACCCACTGCGCTAATGTATGGCACGCT
AGACATCAACGAGGCCGTAAGGGCGCAGATGGAGACTGGCATCATAGGCCTAGTAGCTAACCCTGTGGCTGCGCTCCTCT
ACTTCCTCGCAGCAATGCTGATAACCGATAGGATACCCTTCGACCTTGTGCTAGGCGAGCAGGAGATCGTGAATGGGCCC
TACACCGAGTACAGTGGGTTCCTCTACGTGCTATCCATGGCGCTCGACTATGCCAAGCTTTACGCGCTAATGATGCTATT
CACCGACCTCTTCCTAGGCGGCTGGGCTCCATTCACTGGCGAGATCACTGGCAGCTTGGCGGTGTTCCTCAAGACGGTGG
TGGTAATGCTCATAGCAGTATTCCTACGCTCGGTCTACGGTAGGATGAGGCTAGACAAGATGGTCTCAATGTTCTGGGGC
CGCTTCATGCCCCTAGCCTTTGCCGCCCTCATACTTGCAGTATTCGTGCGCTCGCTCTATCTCGGCTAA

Upstream 100 bases:

>100_bases
GTAAGATAGCTGCCCGTGTCCAGATGCGCGTTGGCCCCTACTATGTGTCGCCACAGGCTGGCACGGCGCACTCCAGCTGC
TGGCAGACGGCGTGCGCTTC

Downstream 100 bases:

>100_bases
GTATGGGAAGTAGCGGAGGTGTAGGCTTGGATGAGCCAGAGCGGGCAACCCGGAGCCGGGCAGACGGCAAGCAGTGGTGT
TAGGGTCCGCAGGGTTAGTA

Product: NADH-ubiquinone oxidoreductase chain 1

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MFQEIIVPFETERLAFAAAPILAFTIAVLPLTVIPGGPGVYGFTSPYSMLIAYALLSLTSIVILVMGWAASNKFTLIGAG
REILTAIAGEVVLLASILPTALMYGTLDINEAVRAQMETGIIGLVANPVAALLYFLAAMLITDRIPFDLVLGEQEIVNGP
YTEYSGFLYVLSMALDYAKLYALMMLFTDLFLGGWAPFTGEITGSLAVFLKTVVVMLIAVFLRSVYGRMRLDKMVSMFWG
RFMPLAFAALILAVFVRSLYLG

Sequences:

>Translated_262_residues
MFQEIIVPFETERLAFAAAPILAFTIAVLPLTVIPGGPGVYGFTSPYSMLIAYALLSLTSIVILVMGWAASNKFTLIGAG
REILTAIAGEVVLLASILPTALMYGTLDINEAVRAQMETGIIGLVANPVAALLYFLAAMLITDRIPFDLVLGEQEIVNGP
YTEYSGFLYVLSMALDYAKLYALMMLFTDLFLGGWAPFTGEITGSLAVFLKTVVVMLIAVFLRSVYGRMRLDKMVSMFWG
RFMPLAFAALILAVFVRSLYLG
>Mature_262_residues
MFQEIIVPFETERLAFAAAPILAFTIAVLPLTVIPGGPGVYGFTSPYSMLIAYALLSLTSIVILVMGWAASNKFTLIGAG
REILTAIAGEVVLLASILPTALMYGTLDINEAVRAQMETGIIGLVANPVAALLYFLAAMLITDRIPFDLVLGEQEIVNGP
YTEYSGFLYVLSMALDYAKLYALMMLFTDLFLGGWAPFTGEITGSLAVFLKTVVVMLIAVFLRSVYGRMRLDKMVSMFWG
RFMPLAFAALILAVFVRSLYLG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=199, Percent_Identity=30.1507537688442, Blast_Score=91, Evalue=8e-19,
Organism=Escherichia coli, GI1788618, Length=252, Percent_Identity=26.984126984127, Blast_Score=98, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 28488; Mature: 28488

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQEIIVPFETERLAFAAAPILAFTIAVLPLTVIPGGPGVYGFTSPYSMLIAYALLSLTS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
IVILVMGWAASNKFTLIGAGREILTAIAGEVVLLASILPTALMYGTLDINEAVRAQMETG
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
IIGLVANPVAALLYFLAAMLITDRIPFDLVLGEQEIVNGPYTEYSGFLYVLSMALDYAKL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHH
YALMMLFTDLFLGGWAPFTGEITGSLAVFLKTVVVMLIAVFLRSVYGRMRLDKMVSMFWG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFMPLAFAALILAVFVRSLYLG
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFQEIIVPFETERLAFAAAPILAFTIAVLPLTVIPGGPGVYGFTSPYSMLIAYALLSLTS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
IVILVMGWAASNKFTLIGAGREILTAIAGEVVLLASILPTALMYGTLDINEAVRAQMETG
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
IIGLVANPVAALLYFLAAMLITDRIPFDLVLGEQEIVNGPYTEYSGFLYVLSMALDYAKL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHH
YALMMLFTDLFLGGWAPFTGEITGSLAVFLKTVVVMLIAVFLRSVYGRMRLDKMVSMFWG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFMPLAFAALILAVFVRSLYLG
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA