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The map label for this gene is 124026933

Identifier: 124026933

GI number: 124026933

Start: 22465

End: 23706

Strand: Direct

Name: 124026933

Synonym: Hbut_0030

Alternate gene names: NA

Gene position: 22465-23706 (Clockwise)

Preceding gene: 124026931

Following gene: 124026934

Centisome position: 1.35

GC content: 53.14

Gene sequence:

>1242_bases
ATGAAGGTCTACATTGTTGACCACTTTACGGGTAACTACGCGCTAAATGAGGATAAGGACGTTGTAGCCTACGAGCATGC
ACCAAAGAGCCTAGATGACATGGTTGAAGAGGCACTAAAGGTAGAGCGTGGCGAGGTTCCAGCTGCATTCCTACGGCTCC
TCGAGAAGCTAAAGGAGGTGGGAGTAAAGACCGTAGTAGTTGAGAGGGAAGAACTCGCAAAGGAGGCTATAAGTAGGGGG
TTTGAGGCGGAGGTTAAGCCTGCAAACGAGGTTGCCAGGTACTTCAGGGGCAATGTTGTAGACATTGTTACCGGTACGGG
TTTTGTGCCGAGCAGGGAGGAGTACTACAAGCTTCTCCACGAGTTTAGCATGGAGCTTACACGGAGAAAGCTGCGTAGAG
CAGCACAGAAGCGTGACCTCCTCGCAGCACAAGCCATAAGAGCTATAGACGATATTGACAAGACTACAAACCTGTTCGCT
GCAAGGCTTAGGGAGTGGTATAGCCTCCACTTCCCAGAGCTAGACGACTTGGTCCGCGAGCACGAGGATTACGTGAGGAT
TGTAGCTGAGCTAGGTCATCGTGACAATATAACTGTTGAGAATCTTGTCAAGCTAGGCTTTAGCGAGGAGAAGGCCAAGA
AGATAGCTGAGGCGGCAGCAAAGAGCATGGGTGCGGACTACCCAGAGTTCGACATCAAGCCTATGCAGCGGCTTGCACAG
ATAACCCTGGAGCTATACAAGCTTAGGAGAGACCTAGCAGACTACATAGCCCAGGTAATGAAGGAGGTAGCACCAAACAT
AACCGCGCTAGTAGGTCCACTCCTAGGTGCAAGGCTCATAAGCCTTGCAGGCAGCCTAGAGGAGCTAGCATTCTTGCCGG
CCAGCACAATTCAAGTGCTGGGCGCCGAGAAGGCCTTGTTCAGAGCGCTGCGTACCGGTGGCAAGCCGCCAAAGCACGGC
GTTATCTTCCAGTACCCCGATATACACCGCAGCCCGCGCTGGCAGCGCGGTAAGATAGCTAGAGCGCTTGCTGCAAAGCT
TGCAATTGCTGCCAAGGTCGACTACTTCACTGGCAGGTTCATAGGCGATAAGCTAAAGGAGGCTTTGAGGAGGAGGATAG
AGGAGATCAAGAGGATATACAAGAAGCCGCCGAAGAGGAAGGAGGTTGGGCCAGCACCCAGGCCAGCGAAGCCGGCAAGG
AGGAAACGTGGCAAGCGCGGTAAGGGTAAAGGCAGGAAGTAG

Upstream 100 bases:

>100_bases
GCTATTGCTCCCCTTCACCCTACCCGGTGGAATGGAATATTTAAATAGTCACCTCCACATTGATAGCCCTAAGGGCGAGG
TAAGGAGGTATAAGGTGAGT

Downstream 100 bases:

>100_bases
CCTACTCCATGTGATAGGGGGTGTAAGGTATGGTTGAAGTAGTTAATGTGTATGAGCATGAGAAGTATAAGGGTGTATAC
ATCGTAGAGCTTGAGGATGG

Product: C/D box methylation guide ribonucleoprotein complex aNOP56 subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKVYIVDHFTGNYALNEDKDVVAYEHAPKSLDDMVEEALKVERGEVPAAFLRLLEKLKEVGVKTVVVEREELAKEAISRG
FEAEVKPANEVARYFRGNVVDIVTGTGFVPSREEYYKLLHEFSMELTRRKLRRAAQKRDLLAAQAIRAIDDIDKTTNLFA
ARLREWYSLHFPELDDLVREHEDYVRIVAELGHRDNITVENLVKLGFSEEKAKKIAEAAAKSMGADYPEFDIKPMQRLAQ
ITLELYKLRRDLADYIAQVMKEVAPNITALVGPLLGARLISLAGSLEELAFLPASTIQVLGAEKALFRALRTGGKPPKHG
VIFQYPDIHRSPRWQRGKIARALAAKLAIAAKVDYFTGRFIGDKLKEALRRRIEEIKRIYKKPPKRKEVGPAPRPAKPAR
RKRGKRGKGKGRK

Sequences:

>Translated_413_residues
MKVYIVDHFTGNYALNEDKDVVAYEHAPKSLDDMVEEALKVERGEVPAAFLRLLEKLKEVGVKTVVVEREELAKEAISRG
FEAEVKPANEVARYFRGNVVDIVTGTGFVPSREEYYKLLHEFSMELTRRKLRRAAQKRDLLAAQAIRAIDDIDKTTNLFA
ARLREWYSLHFPELDDLVREHEDYVRIVAELGHRDNITVENLVKLGFSEEKAKKIAEAAAKSMGADYPEFDIKPMQRLAQ
ITLELYKLRRDLADYIAQVMKEVAPNITALVGPLLGARLISLAGSLEELAFLPASTIQVLGAEKALFRALRTGGKPPKHG
VIFQYPDIHRSPRWQRGKIARALAAKLAIAAKVDYFTGRFIGDKLKEALRRRIEEIKRIYKKPPKRKEVGPAPRPAKPAR
RKRGKRGKGKGRK
>Mature_413_residues
MKVYIVDHFTGNYALNEDKDVVAYEHAPKSLDDMVEEALKVERGEVPAAFLRLLEKLKEVGVKTVVVEREELAKEAISRG
FEAEVKPANEVARYFRGNVVDIVTGTGFVPSREEYYKLLHEFSMELTRRKLRRAAQKRDLLAAQAIRAIDDIDKTTNLFA
ARLREWYSLHFPELDDLVREHEDYVRIVAELGHRDNITVENLVKLGFSEEKAKKIAEAAAKSMGADYPEFDIKPMQRLAQ
ITLELYKLRRDLADYIAQVMKEVAPNITALVGPLLGARLISLAGSLEELAFLPASTIQVLGAEKALFRALRTGGKPPKHG
VIFQYPDIHRSPRWQRGKIARALAAKLAIAAKVDYFTGRFIGDKLKEALRRRIEEIKRIYKKPPKRKEVGPAPRPAKPAR
RKRGKRGKGKGRK

Specific function: Unknown

COG id: COG1498

COG function: function code J; Protein implicated in ribosomal biogenesis, Nop56p homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Nop domain [H]

Homologues:

Organism=Homo sapiens, GI32483374, Length=290, Percent_Identity=36.8965517241379, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI7706254, Length=270, Percent_Identity=37.7777777777778, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI221136939, Length=253, Percent_Identity=28.8537549407115, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17509449, Length=305, Percent_Identity=37.3770491803279, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17562296, Length=255, Percent_Identity=39.6078431372549, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17510923, Length=304, Percent_Identity=26.3157894736842, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6324886, Length=325, Percent_Identity=35.6923076923077, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6323226, Length=255, Percent_Identity=38.4313725490196, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6321528, Length=271, Percent_Identity=28.4132841328413, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI17137636, Length=291, Percent_Identity=37.8006872852234, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI28572126, Length=275, Percent_Identity=38.1818181818182, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI21357435, Length=259, Percent_Identity=27.7992277992278, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012976
- InterPro:   IPR002687 [H]

Pfam domain/function: PF01798 Nop; PF08060 NOSIC [H]

EC number: NA

Molecular weight: Translated: 46856; Mature: 46856

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYIVDHFTGNYALNEDKDVVAYEHAPKSLDDMVEEALKVERGEVPAAFLRLLEKLKEV
CEEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GVKTVVVEREELAKEAISRGFEAEVKPANEVARYFRGNVVDIVTGTGFVPSREEYYKLLH
CHHHEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
EFSMELTRRKLRRAAQKRDLLAAQAIRAIDDIDKTTNLFAARLREWYSLHFPELDDLVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
HEDYVRIVAELGHRDNITVENLVKLGFSEEKAKKIAEAAAKSMGADYPEFDIKPMQRLAQ
HHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ITLELYKLRRDLADYIAQVMKEVAPNITALVGPLLGARLISLAGSLEELAFLPASTIQVL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHH
GAEKALFRALRTGGKPPKHGVIFQYPDIHRSPRWQRGKIARALAAKLAIAAKVDYFTGRF
HHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGDKLKEALRRRIEEIKRIYKKPPKRKEVGPAPRPAKPARRKRGKRGKGKGRK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKVYIVDHFTGNYALNEDKDVVAYEHAPKSLDDMVEEALKVERGEVPAAFLRLLEKLKEV
CEEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
GVKTVVVEREELAKEAISRGFEAEVKPANEVARYFRGNVVDIVTGTGFVPSREEYYKLLH
CHHHEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
EFSMELTRRKLRRAAQKRDLLAAQAIRAIDDIDKTTNLFAARLREWYSLHFPELDDLVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
HEDYVRIVAELGHRDNITVENLVKLGFSEEKAKKIAEAAAKSMGADYPEFDIKPMQRLAQ
HHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ITLELYKLRRDLADYIAQVMKEVAPNITALVGPLLGARLISLAGSLEELAFLPASTIQVL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHH
GAEKALFRALRTGGKPPKHGVIFQYPDIHRSPRWQRGKIARALAAKLAIAAKVDYFTGRF
HHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGDKLKEALRRRIEEIKRIYKKPPKRKEVGPAPRPAKPARRKRGKRGKGKGRK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]