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The map label for this gene is 124026919

Identifier: 124026919

GI number: 124026919

Start: 11925

End: 12986

Strand: Reverse

Name: 124026919

Synonym: Hbut_0016

Alternate gene names: NA

Gene position: 12986-11925 (Counterclockwise)

Preceding gene: 124026920

Following gene: 124026917

Centisome position: 0.78

GC content: 50.85

Gene sequence:

>1062_bases
ATGACTATTAGGTATGATTACGTAATCATAGGGGCCGGCCCGGCTGGCGCAGCGCTAGCACGTTTCCTAACCGATAAGGG
GTTTAGGGTCAAGGTATATGACATAGCCCCATACCCTGGATTTAAGCCGTGCGGATGGGCTGTCCCGCTGCAAGTAGAGG
ACTACATTGACATACCGGTTGATGCTATCCTAACTGAGATACGCGGCTTTAGAGTCTATGTCGACGGCGAACTAGCCCAT
GAGAAGTACGGCAAACTCCAGGGCTACATTATAGACAAGCCTGCATTCCTCAAACACTTGCTCGAAGGCATACCTTTCGA
GCGGAGGATTGTGGAGCTTACACCTGAGCTTAGGCCTGTCAAGCAGCTCGAAGAAGCAAAGGAAATCGTTGTAGCTACGG
GCTCGGTGACTCCACACCGCGGCATTAGGGATCAAATATATGCTGTCCAGGCAATAGTCAGGACTAGCGAGCCACACGAC
ACTACTATTATGGAGCTGTGGTTTGACAGCAGCCTCGTAGGCTACTACTGGGTCTTCCCACGCTCTCGCTATACCGTAGA
CATTGGCGTGGGCGGCTATGGCGAGCCAAGAGAGTTTCGCCAGAAGCTTATAGAGTTCATAAGGAAGAGAGTGAAAGGCC
CAGTCGAGATGACACCAATACGCGGCGCAGCTATAAACATTGGAGGAGCAAATCCAAGCCTCCTCATAAGGGATATACCG
GTGATAGGTGAGGCTGCAGGCTTTGTATACCCGCTTACCGGCGAGGGTATAAGGCCCTCAATAGCATCCGCATATGCCCT
GACAAGATACATAGCTAGCGGCGAGGACCCAGGCAAAACACTGAGCAGAATAGTCCACTGGATAGGCGTACAACGCAAAC
TTCTCGAGAAAATAAAGACAGCAAGGCCCGAAACAAGAGCAAAGCTACTAAGAAGTATACCAACCGACCTACTACCACTC
ATAGGAATAGGCAATGTCTCAACAATCAAGCTGCTAGGGCTAATAGCCAGGATGCCCTCTAGGCTAGCAGAAATCCTCCG
TACACTAGTGCAGAAGACCTAG

Upstream 100 bases:

>100_bases
GCGCAATGCTTGGTCCAGACATTGAGCGCGTCAAAGCCTATACGTCCCGGGTAACCCGGTTTAACCCTCCACGTCATGTA
CCCCGAGGGGATAACCGGGT

Downstream 100 bases:

>100_bases
CCCCCTAGGCGAGTCCTCTCAGGCTTAAGAGGGGGCGAGGACTCAACCAGCATTGTCTACACGGGCTGTGAGGAGTAGCA
AACCGTGCGACCCAACCGGC

Product: dehydrogenase FixC

Products: NA

Alternate protein names: DGGGPL reductase; 2,3-di-O-geranylgeranylglyceryl phosphate reductase; Geranylgeranyl reductase; GGR [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MTIRYDYVIIGAGPAGAALARFLTDKGFRVKVYDIAPYPGFKPCGWAVPLQVEDYIDIPVDAILTEIRGFRVYVDGELAH
EKYGKLQGYIIDKPAFLKHLLEGIPFERRIVELTPELRPVKQLEEAKEIVVATGSVTPHRGIRDQIYAVQAIVRTSEPHD
TTIMELWFDSSLVGYYWVFPRSRYTVDIGVGGYGEPREFRQKLIEFIRKRVKGPVEMTPIRGAAINIGGANPSLLIRDIP
VIGEAAGFVYPLTGEGIRPSIASAYALTRYIASGEDPGKTLSRIVHWIGVQRKLLEKIKTARPETRAKLLRSIPTDLLPL
IGIGNVSTIKLLGLIARMPSRLAEILRTLVQKT

Sequences:

>Translated_353_residues
MTIRYDYVIIGAGPAGAALARFLTDKGFRVKVYDIAPYPGFKPCGWAVPLQVEDYIDIPVDAILTEIRGFRVYVDGELAH
EKYGKLQGYIIDKPAFLKHLLEGIPFERRIVELTPELRPVKQLEEAKEIVVATGSVTPHRGIRDQIYAVQAIVRTSEPHD
TTIMELWFDSSLVGYYWVFPRSRYTVDIGVGGYGEPREFRQKLIEFIRKRVKGPVEMTPIRGAAINIGGANPSLLIRDIP
VIGEAAGFVYPLTGEGIRPSIASAYALTRYIASGEDPGKTLSRIVHWIGVQRKLLEKIKTARPETRAKLLRSIPTDLLPL
IGIGNVSTIKLLGLIARMPSRLAEILRTLVQKT
>Mature_352_residues
TIRYDYVIIGAGPAGAALARFLTDKGFRVKVYDIAPYPGFKPCGWAVPLQVEDYIDIPVDAILTEIRGFRVYVDGELAHE
KYGKLQGYIIDKPAFLKHLLEGIPFERRIVELTPELRPVKQLEEAKEIVVATGSVTPHRGIRDQIYAVQAIVRTSEPHDT
TIMELWFDSSLVGYYWVFPRSRYTVDIGVGGYGEPREFRQKLIEFIRKRVKGPVEMTPIRGAAINIGGANPSLLIRDIPV
IGEAAGFVYPLTGEGIRPSIASAYALTRYIASGEDPGKTLSRIVHWIGVQRKLLEKIKTARPETRAKLLRSIPTDLLPLI
GIGNVSTIKLLGLIARMPSRLAEILRTLVQKT

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011777
- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: NA

Molecular weight: Translated: 39373; Mature: 39241

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00265 PANCREATIC_HORMONE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRYDYVIIGAGPAGAALARFLTDKGFRVKVYDIAPYPGFKPCGWAVPLQVEDYIDIPV
CEEEEEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEECEEECCCCCCCH
DAILTEIRGFRVYVDGELAHEKYGKLQGYIIDKPAFLKHLLEGIPFERRIVELTPELRPV
HHHHHHHCCEEEEECCCHHHHHHCCCCCEEECCHHHHHHHHHCCCCCHHHHHHCCCCCHH
KQLEEAKEIVVATGSVTPHRGIRDQIYAVQAIVRTSEPHDTTIMELWFDSSLVGYYWVFP
HHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEC
RSRYTVDIGVGGYGEPREFRQKLIEFIRKRVKGPVEMTPIRGAAINIGGANPSLLIRDIP
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCCCCEEEEECC
VIGEAAGFVYPLTGEGIRPSIASAYALTRYIASGEDPGKTLSRIVHWIGVQRKLLEKIKT
CEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARPETRAKLLRSIPTDLLPLIGIGNVSTIKLLGLIARMPSRLAEILRTLVQKT
CCCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIRYDYVIIGAGPAGAALARFLTDKGFRVKVYDIAPYPGFKPCGWAVPLQVEDYIDIPV
EEEEEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEECEEECCCCCCCH
DAILTEIRGFRVYVDGELAHEKYGKLQGYIIDKPAFLKHLLEGIPFERRIVELTPELRPV
HHHHHHHCCEEEEECCCHHHHHHCCCCCEEECCHHHHHHHHHCCCCCHHHHHHCCCCCHH
KQLEEAKEIVVATGSVTPHRGIRDQIYAVQAIVRTSEPHDTTIMELWFDSSLVGYYWVFP
HHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEC
RSRYTVDIGVGGYGEPREFRQKLIEFIRKRVKGPVEMTPIRGAAINIGGANPSLLIRDIP
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCCCCEEEEECC
VIGEAAGFVYPLTGEGIRPSIASAYALTRYIASGEDPGKTLSRIVHWIGVQRKLLEKIKT
CEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARPETRAKLLRSIPTDLLPLIGIGNVSTIKLLGLIARMPSRLAEILRTLVQKT
CCCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA