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The map label for this gene is galE [H]

Identifier: 123967065

GI number: 123967065

Start: 1615832

End: 1616878

Strand: Reverse

Name: galE [H]

Synonym: P9515_18321

Alternate gene names: 123967065

Gene position: 1616878-1615832 (Counterclockwise)

Preceding gene: 123967066

Following gene: 123967064

Centisome position: 94.88

GC content: 35.43

Gene sequence:

>1047_bases
ATGTCTACTGTAATAGTTGCTGGAGGTGCAGGTTATATTGGCTCTCATACTGTAAGAGAACTTCAGAATGAAGGTTTTGA
ACCTATCGTACTAGATAATTTAGTTTATGGTCATAGAAATATTGTCGAGGATGTCTTAGCAGTTCCTTTAGTAATTGGTC
AAGTAGGCGACAAGCCACTTTTAAAAAAACTTTTTTCAGGAGAACATCCCCTAACTAGAGGTAAAGATATAAAGGGGATT
ATGCATTTTGCTGCTTACGCTTATGTGGGGGAATCTGTTGTTGACCCTGCTAAATACTATAAAAACAACTTAGTAGAAAC
AATCAGCCTCTTAGAGGCTTTGTTGGAAGATTCCAAAAAAAGAAACTCTCAACCAATCCCGATTGTTTTTAGCTCATCTT
GTGCGACATATGGGATACCTCTAGAAGCCGAAATCCCCATAATTGAAAGGACTCCACAGAATCCGATCAACCCTTATGGA
AGGAGTAAATTAATGATGGAGAAAATTTTAATTGATTATCACAAAGCTTATGAGCTGCCTGTATCCATACTTCGTTACTT
CAATGCTGCAGGCGCGGACATTAATGGGGACATTGGTGAAGATCATAATCCAGAAACACATTTGATTCCTTTAGTACTTG
AGGCTCTTTCTGATAAAGAGGGTTTTTTAAAGGTTAATGGTATTGATTATCCAACATTTGATGGCACATGTATAAGAGAT
TACGTACATGTAAGTGATTTAGCAAAAGCTCATGTTTTGGCTTTAAATAAAATAATGAATGATAAAAGTTTATCAATTTA
TAATCTTGGAAATGGTAAAGGATATTCAATAATGGAAGTTATAGATGCTTCAAAAAAAGTTACTGGGAAAGAAATTAGAA
TATTACAATCCAAAAGACGGCAAGGCGATCCCCCTGTACTTATTTCCTCGCCTGAAAAAGCGAAGAAGGAATTGTTATGG
AAACCAGAATTCCAAGATTTAGAAAGCATCATACGGACTGCTTGGAATTGGTATCTTTTTAAGAAAAAATTTAACTCCAA
CAAATAA

Upstream 100 bases:

>100_bases
ATGTAGCTCAGTGGTAGAGCATCTCCTTGCCAAGGAGAATGTCGAGAGTTCGAATCTCTTCATCCGCTTTTCAAAAATTA
TGTTAAAGACAGGTTGATAT

Downstream 100 bases:

>100_bases
ATCAATTGAACTTAAAATCTCCTATGAAAAGTAAATAGAATAAAATTATTACACCATAATAAGGTAAGTATATTTTATTG
ATTTAGGTTCTTATCTACCA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSTVIVAGGAGYIGSHTVRELQNEGFEPIVLDNLVYGHRNIVEDVLAVPLVIGQVGDKPLLKKLFSGEHPLTRGKDIKGI
MHFAAYAYVGESVVDPAKYYKNNLVETISLLEALLEDSKKRNSQPIPIVFSSSCATYGIPLEAEIPIIERTPQNPINPYG
RSKLMMEKILIDYHKAYELPVSILRYFNAAGADINGDIGEDHNPETHLIPLVLEALSDKEGFLKVNGIDYPTFDGTCIRD
YVHVSDLAKAHVLALNKIMNDKSLSIYNLGNGKGYSIMEVIDASKKVTGKEIRILQSKRRQGDPPVLISSPEKAKKELLW
KPEFQDLESIIRTAWNWYLFKKKFNSNK

Sequences:

>Translated_348_residues
MSTVIVAGGAGYIGSHTVRELQNEGFEPIVLDNLVYGHRNIVEDVLAVPLVIGQVGDKPLLKKLFSGEHPLTRGKDIKGI
MHFAAYAYVGESVVDPAKYYKNNLVETISLLEALLEDSKKRNSQPIPIVFSSSCATYGIPLEAEIPIIERTPQNPINPYG
RSKLMMEKILIDYHKAYELPVSILRYFNAAGADINGDIGEDHNPETHLIPLVLEALSDKEGFLKVNGIDYPTFDGTCIRD
YVHVSDLAKAHVLALNKIMNDKSLSIYNLGNGKGYSIMEVIDASKKVTGKEIRILQSKRRQGDPPVLISSPEKAKKELLW
KPEFQDLESIIRTAWNWYLFKKKFNSNK
>Mature_347_residues
STVIVAGGAGYIGSHTVRELQNEGFEPIVLDNLVYGHRNIVEDVLAVPLVIGQVGDKPLLKKLFSGEHPLTRGKDIKGIM
HFAAYAYVGESVVDPAKYYKNNLVETISLLEALLEDSKKRNSQPIPIVFSSSCATYGIPLEAEIPIIERTPQNPINPYGR
SKLMMEKILIDYHKAYELPVSILRYFNAAGADINGDIGEDHNPETHLIPLVLEALSDKEGFLKVNGIDYPTFDGTCIRDY
VHVSDLAKAHVLALNKIMNDKSLSIYNLGNGKGYSIMEVIDASKKVTGKEIRILQSKRRQGDPPVLISSPEKAKKELLWK
PEFQDLESIIRTAWNWYLFKKKFNSNK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=348, Percent_Identity=37.3563218390805, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI56118217, Length=348, Percent_Identity=37.3563218390805, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI189083684, Length=348, Percent_Identity=37.3563218390805, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI7657641, Length=348, Percent_Identity=26.1494252873563, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1786974, Length=352, Percent_Identity=36.6477272727273, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1788353, Length=372, Percent_Identity=28.7634408602151, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI48994969, Length=370, Percent_Identity=27.027027027027, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790049, Length=285, Percent_Identity=28.7719298245614, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=351, Percent_Identity=39.8860398860399, Blast_Score=214, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI71982038, Length=353, Percent_Identity=39.6600566572238, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17539532, Length=349, Percent_Identity=24.3553008595989, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17568069, Length=348, Percent_Identity=25.5747126436782, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=348, Percent_Identity=37.3563218390805, Blast_Score=193, Evalue=4e-50,
Organism=Drosophila melanogaster, GI19923002, Length=351, Percent_Identity=37.3219373219373, Blast_Score=207, Evalue=9e-54,
Organism=Drosophila melanogaster, GI21356223, Length=323, Percent_Identity=26.3157894736842, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38894; Mature: 38763

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVIVAGGAGYIGSHTVRELQNEGFEPIVLDNLVYGHRNIVEDVLAVPLVIGQVGDKPL
CCEEEEECCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LKKLFSGEHPLTRGKDIKGIMHFAAYAYVGESVVDPAKYYKNNLVETISLLEALLEDSKK
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RNSQPIPIVFSSSCATYGIPLEAEIPIIERTPQNPINPYGRSKLMMEKILIDYHKAYELP
CCCCCCCEEEECCCCEECCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VSILRYFNAAGADINGDIGEDHNPETHLIPLVLEALSDKEGFLKVNGIDYPTFDGTCIRD
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHH
YVHVSDLAKAHVLALNKIMNDKSLSIYNLGNGKGYSIMEVIDASKKVTGKEIRILQSKRR
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
QGDPPVLISSPEKAKKELLWKPEFQDLESIIRTAWNWYLFKKKFNSNK
CCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEHHCCCCC
>Mature Secondary Structure 
STVIVAGGAGYIGSHTVRELQNEGFEPIVLDNLVYGHRNIVEDVLAVPLVIGQVGDKPL
CEEEEECCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LKKLFSGEHPLTRGKDIKGIMHFAAYAYVGESVVDPAKYYKNNLVETISLLEALLEDSKK
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RNSQPIPIVFSSSCATYGIPLEAEIPIIERTPQNPINPYGRSKLMMEKILIDYHKAYELP
CCCCCCCEEEECCCCEECCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VSILRYFNAAGADINGDIGEDHNPETHLIPLVLEALSDKEGFLKVNGIDYPTFDGTCIRD
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHH
YVHVSDLAKAHVLALNKIMNDKSLSIYNLGNGKGYSIMEVIDASKKVTGKEIRILQSKRR
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
QGDPPVLISSPEKAKKELLWKPEFQDLESIIRTAWNWYLFKKKFNSNK
CCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]