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The map label for this gene is mcrA

Identifier: 123966943

GI number: 123966943

Start: 1512447

End: 1513010

Strand: Direct

Name: mcrA

Synonym: P9515_17101

Alternate gene names: NA

Gene position: 1512447-1513010 (Clockwise)

Preceding gene: 123966939

Following gene: 123966974

Centisome position: 88.75

GC content: 35.11

Gene sequence:

>564_bases
ATGCGCTTAATTAAATATACCGCTAGCATGACATGTAAAATGATTTTTGGCATGAGCCAGACACTTGTTTTAAATGCTTC
TTATGAACCTTTAAATATAACTTCTTGGCGAAGAGCTATCATTTTAATGATTAAAGGTAAAGCAGAAAGTTTAGAAGAGG
ATCAATCATACTTAATACATTCTGGTCAAAAACTGCCTACTGTTATAAGGCTTCGTTATTACGTCAAAGTTCCTTTTAGA
GAAGTTGCCCTTACAAGAAAAAATATACTTCTTAGAGACAATAATTCTTGCCAATATTGCAACCATAGAGGAAGTGATTT
ATCGATAGATCATGTTTTGCCAAGGAGCAGGGGTGGTACCGATAATTGGGAAAATGTAACAACAGCCTGTCTAAGATGTA
ATGTTCAAAAAGGTAGTAGAACTCCTGAAGAAGCAAATATGCCTTTAAAAAGAAAGCCATATCGCCCATTAAGCAATCTG
AATTTTGAAGCGACGAGACAAATAGACTCTGGGAAACACAAAGAGTGGAGTAAATATGTGATCGGTTTAGCTGCTAAAAA
CTAA

Upstream 100 bases:

>100_bases
CTCTTTGAGTTGGATCAATTTCTCCTTGAAAATTTAAATTAGTATCCACATTATTTTTTCGATTATTAAAGGAAATCTGC
ATTAATGTTTGCGTAGTTAT

Downstream 100 bases:

>100_bases
AAAAATTTAATTCTCATTCTCATTAAAATCCTCCATTATCCTCTTTTGTTCTTGAGCTATACAAGCATCTATAACTTCAT
CTAATTGTCCTGCCAGAATT

Product: HNH endonuclease family protein

Products: NA

Alternate protein names: HNH Endonuclease Family Protein; Endonuclease; Restriction Endonuclease; HNH Endonuclease Domain Protein; HNH Endonuclease Domain-Containing Protein; Hnh Endonuclease; HNH Nuclease; McrA/HNH Family Nuclease; 5-Methylcytosine-Specific Restriction A; 5-Methylcytosine-Specific Restriction Protein; Restriction Endonuclease McrA/HNH Family; HNH EndonucleaseHNH Nuclease; HNH Family Endonuclease; LOW QUALITY PROTEIN Endonuclease; Hnh Endonuclease Domain Protein; 5-Methylcytosine-Specific Restriction Protein A

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MRLIKYTASMTCKMIFGMSQTLVLNASYEPLNITSWRRAIILMIKGKAESLEEDQSYLIHSGQKLPTVIRLRYYVKVPFR
EVALTRKNILLRDNNSCQYCNHRGSDLSIDHVLPRSRGGTDNWENVTTACLRCNVQKGSRTPEEANMPLKRKPYRPLSNL
NFEATRQIDSGKHKEWSKYVIGLAAKN

Sequences:

>Translated_187_residues
MRLIKYTASMTCKMIFGMSQTLVLNASYEPLNITSWRRAIILMIKGKAESLEEDQSYLIHSGQKLPTVIRLRYYVKVPFR
EVALTRKNILLRDNNSCQYCNHRGSDLSIDHVLPRSRGGTDNWENVTTACLRCNVQKGSRTPEEANMPLKRKPYRPLSNL
NFEATRQIDSGKHKEWSKYVIGLAAKN
>Mature_187_residues
MRLIKYTASMTCKMIFGMSQTLVLNASYEPLNITSWRRAIILMIKGKAESLEEDQSYLIHSGQKLPTVIRLRYYVKVPFR
EVALTRKNILLRDNNSCQYCNHRGSDLSIDHVLPRSRGGTDNWENVTTACLRCNVQKGSRTPEEANMPLKRKPYRPLSNL
NFEATRQIDSGKHKEWSKYVIGLAAKN

Specific function: Unknown

COG id: COG1403

COG function: function code V; Restriction endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 21522; Mature: 21522

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIKYTASMTCKMIFGMSQTLVLNASYEPLNITSWRRAIILMIKGKAESLEEDQSYLIH
CEEEEEHHHHHEEHHHCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHH
SGQKLPTVIRLRYYVKVPFREVALTRKNILLRDNNSCQYCNHRGSDLSIDHVLPRSRGGT
CCCCCCEEEEEEEEEECCHHHHHHHHCEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCC
DNWENVTTACLRCNVQKGSRTPEEANMPLKRKPYRPLSNLNFEATRQIDSGKHKEWSKYV
CCHHHHHHHHHEEECCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEE
IGLAAKN
EEEEECC
>Mature Secondary Structure
MRLIKYTASMTCKMIFGMSQTLVLNASYEPLNITSWRRAIILMIKGKAESLEEDQSYLIH
CEEEEEHHHHHEEHHHCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHH
SGQKLPTVIRLRYYVKVPFREVALTRKNILLRDNNSCQYCNHRGSDLSIDHVLPRSRGGT
CCCCCCEEEEEEEEEECCHHHHHHHHCEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCC
DNWENVTTACLRCNVQKGSRTPEEANMPLKRKPYRPLSNLNFEATRQIDSGKHKEWSKYV
CCHHHHHHHHHEEECCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEE
IGLAAKN
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA