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The map label for this gene is bioD [H]

Identifier: 123966884

GI number: 123966884

Start: 1443318

End: 1443983

Strand: Direct

Name: bioD [H]

Synonym: P9515_16511

Alternate gene names: 123966884

Gene position: 1443318-1443983 (Clockwise)

Preceding gene: 123966883

Following gene: 123966885

Centisome position: 84.69

GC content: 30.03

Gene sequence:

>666_bases
ATGAGAGCTATAAATAAACAATTTCAATTTGTAATCTGCGGTACAGATACTGATATAGGAAAAACATTAATCAGTTCTTT
TTTTGTAAGGGGATTAAATTCTTTTTATTGGAAGCCTATTCAAAGTGGAATTGGTTCAGAGACTGATAGTCAAGCTGTTG
CACGACTTACAAAAGTAAATAAGGCAAAGATAATCAATGAAGCTTATATCTTTAAAGAACCTGTTTCCCCACATTGGGCA
GCAGAAATAGATCAAAAAGTTATAAACTTTCAGCAATTGAATTTACCAAATGTTGATGGACCATTAATTGTAGAAACTGC
GGGGGGTTTAATGGTTCCAATTACAAGAAACCATTTGCAAATAGATCAAATCAAGAAATGGAACATCCCTGTAATACTTG
TATGTAAAAGCGGTCTTGGGACTCTTAATCATACTCTTTTAAGTATCGAGGCATTAAAAAAAAGAAATATCAAAATTCTA
GGTCTAGTGATTAACGGAAAAAAACACTTAGATAATCCAAAAACATTAACTACATTTAGTAATATTCCTATTATTGCTGA
ATTTCCATTGATTCAGAACATTGGTTCCCATAATTTAGATATAATTTGGGAAGAGTTAAAAATTAAAAATAGATTGATCA
CCTTATTAAGTTCAAAAAATAATTAA

Upstream 100 bases:

>100_bases
CAGTGAATGAATTAAGAAAAATGCAAAAGTTTTGGCCAAAGATAGAAACTAATAGAGTTAACCTTACATGGAAAATTAAT
ATTCAAATATTAAAAAAATC

Downstream 100 bases:

>100_bases
TGAAATCTCAGATATCAACAAACATTAATCAAGATTGGCACCCTCATATATGGCCACCTTTTACTCAGATTACAAATAGC
AAACCCCAAATAGAAGTTAC

Product: putative dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MRAINKQFQFVICGTDTDIGKTLISSFFVRGLNSFYWKPIQSGIGSETDSQAVARLTKVNKAKIINEAYIFKEPVSPHWA
AEIDQKVINFQQLNLPNVDGPLIVETAGGLMVPITRNHLQIDQIKKWNIPVILVCKSGLGTLNHTLLSIEALKKRNIKIL
GLVINGKKHLDNPKTLTTFSNIPIIAEFPLIQNIGSHNLDIIWEELKIKNRLITLLSSKNN

Sequences:

>Translated_221_residues
MRAINKQFQFVICGTDTDIGKTLISSFFVRGLNSFYWKPIQSGIGSETDSQAVARLTKVNKAKIINEAYIFKEPVSPHWA
AEIDQKVINFQQLNLPNVDGPLIVETAGGLMVPITRNHLQIDQIKKWNIPVILVCKSGLGTLNHTLLSIEALKKRNIKIL
GLVINGKKHLDNPKTLTTFSNIPIIAEFPLIQNIGSHNLDIIWEELKIKNRLITLLSSKNN
>Mature_221_residues
MRAINKQFQFVICGTDTDIGKTLISSFFVRGLNSFYWKPIQSGIGSETDSQAVARLTKVNKAKIINEAYIFKEPVSPHWA
AEIDQKVINFQQLNLPNVDGPLIVETAGGLMVPITRNHLQIDQIKKWNIPVILVCKSGLGTLNHTLLSIEALKKRNIKIL
GLVINGKKHLDNPKTLTTFSNIPIIAEFPLIQNIGSHNLDIIWEELKIKNRLITLLSSKNN

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=206, Percent_Identity=27.6699029126214, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324385, Length=220, Percent_Identity=32.7272727272727, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24771; Mature: 24771

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAINKQFQFVICGTDTDIGKTLISSFFVRGLNSFYWKPIQSGIGSETDSQAVARLTKVN
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KAKIINEAYIFKEPVSPHWAAEIDQKVINFQQLNLPNVDGPLIVETAGGLMVPITRNHLQ
HHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCEE
IDQIKKWNIPVILVCKSGLGTLNHTLLSIEALKKRNIKILGLVINGKKHLDNPKTLTTFS
EEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEECHHHCCCCCEEEEEC
NIPIIAEFPLIQNIGSHNLDIIWEELKIKNRLITLLSSKNN
CCCEEEECCHHHHCCCCCCEEEEHHHHHHHHHEEEEECCCC
>Mature Secondary Structure
MRAINKQFQFVICGTDTDIGKTLISSFFVRGLNSFYWKPIQSGIGSETDSQAVARLTKVN
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KAKIINEAYIFKEPVSPHWAAEIDQKVINFQQLNLPNVDGPLIVETAGGLMVPITRNHLQ
HHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCEE
IDQIKKWNIPVILVCKSGLGTLNHTLLSIEALKKRNIKILGLVINGKKHLDNPKTLTTFS
EEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEECHHHCCCCCEEEEEC
NIPIIAEFPLIQNIGSHNLDIIWEELKIKNRLITLLSSKNN
CCCEEEECCHHHHCCCCCCEEEEHHHHHHHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA