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The map label for this gene is fabZ

Identifier: 123966730

GI number: 123966730

Start: 1331427

End: 1331885

Strand: Reverse

Name: fabZ

Synonym: P9515_14971

Alternate gene names: 123966730

Gene position: 1331885-1331427 (Counterclockwise)

Preceding gene: 123966731

Following gene: 123966729

Centisome position: 78.15

GC content: 37.25

Gene sequence:

>459_bases
TTGGACAAGCAATTACTAAGTGAAAATAATCAACTATCTTCTGAGGAAATACTTGGTCTTTTGCCACATAGATTCCCTTT
CGCTCTGGTAGATAGAGTTATAGAACATATTCCGGGACACAAAGCTGTTGCATTGAAAAATGTAACTATAAATGAACCTC
AATTCCAAGGTCACTTCCCAGAAAGACCTTTAATGCCAGGAGTGCTTATTGTTGAATCAATGGCTCAAGTAGGAGGAATT
ATTGTAACTCAAATGCCCGACCTCCCAAAAGGACTCTTTGTTTTTGCAGGAATTAATAATGTCAAATTTAGAAGACCGGT
GCTACCTGGCGATCAATTAGTGATTACCTGTGAGTTATTAAGCATTAAAAGACAAAGGTTTGGGAAGGTAAAAGGTGAAG
CACATGTTGATGGGAAATTAGTTTGCTCAGGCGAATTGATGTTTTCATTAGTTGATTAA

Upstream 100 bases:

>100_bases
AGGCTTACCAAAGGCACAAATTTTAGTATATAAGGGATCACATTCTTTAAATGCTTTATTGGCCTCATCATTAAAAAATT
AATTTTATCTTTTTTAAGTT

Downstream 100 bases:

>100_bases
TAAAATGGAGATTAAAAATACCAAACGAAATCCAGATTTTCGAGGTGCGAGAGTGCACCCCAATGCAGTTGTCGATTCAA
GTGCAGAATTGCATGATGGA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MDKQLLSENNQLSSEEILGLLPHRFPFALVDRVIEHIPGHKAVALKNVTINEPQFQGHFPERPLMPGVLIVESMAQVGGI
IVTQMPDLPKGLFVFAGINNVKFRRPVLPGDQLVITCELLSIKRQRFGKVKGEAHVDGKLVCSGELMFSLVD

Sequences:

>Translated_152_residues
MDKQLLSENNQLSSEEILGLLPHRFPFALVDRVIEHIPGHKAVALKNVTINEPQFQGHFPERPLMPGVLIVESMAQVGGI
IVTQMPDLPKGLFVFAGINNVKFRRPVLPGDQLVITCELLSIKRQRFGKVKGEAHVDGKLVCSGELMFSLVD
>Mature_152_residues
MDKQLLSENNQLSSEEILGLLPHRFPFALVDRVIEHIPGHKAVALKNVTINEPQFQGHFPERPLMPGVLIVESMAQVGGI
IVTQMPDLPKGLFVFAGINNVKFRRPVLPGDQLVITCELLSIKRQRFGKVKGEAHVDGKLVCSGELMFSLVD

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=145, Percent_Identity=47.5862068965517, Blast_Score=135, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_PROM5 (A2BY43)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001011811.1
- ProteinModelPortal:   A2BY43
- SMR:   A2BY43
- STRING:   A2BY43
- GeneID:   4720061
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_14971
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   PMAR167542:P9515ORF_1565-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16846; Mature: 16846

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: ACT_SITE 58-58

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKQLLSENNQLSSEEILGLLPHRFPFALVDRVIEHIPGHKAVALKNVTINEPQFQGHFP
CCCCHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECEEECCCCCCCCCC
ERPLMPGVLIVESMAQVGGIIVTQMPDLPKGLFVFAGINNVKFRRPVLPGDQLVITCELL
CCCCCCHHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCEEECCCCCCCCEEEEHHHH
SIKRQRFGKVKGEAHVDGKLVCSGELMFSLVD
HHHHHHHCCCCCCCCCCCEEEECCCEEEEECC
>Mature Secondary Structure
MDKQLLSENNQLSSEEILGLLPHRFPFALVDRVIEHIPGHKAVALKNVTINEPQFQGHFP
CCCCHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECEEECCCCCCCCCC
ERPLMPGVLIVESMAQVGGIIVTQMPDLPKGLFVFAGINNVKFRRPVLPGDQLVITCELL
CCCCCCHHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCEEECCCCCCCCEEEEHHHH
SIKRQRFGKVKGEAHVDGKLVCSGELMFSLVD
HHHHHHHCCCCCCCCCCCEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA