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The map label for this gene is hemN [C]

Identifier: 123966705

GI number: 123966705

Start: 1309436

End: 1310659

Strand: Reverse

Name: hemN [C]

Synonym: P9515_14721

Alternate gene names: 123966705

Gene position: 1310659-1309436 (Counterclockwise)

Preceding gene: 123966712

Following gene: 123966698

Centisome position: 76.91

GC content: 30.8

Gene sequence:

>1224_bases
ATGAATAAGTTTCCAAGAAGTGCTTACGTACATATACCTTTTTGCCATAGAAGATGCTTCTACTGTGATTTTGCAGTTGT
ACCTCTAGGTAACAATATTGAAAGTTTAAATGGCTATGGAAGTAATACTGTAAAAGAATATTTGACCTATTTAGATAAAG
AAATATTGTCAATCAAACATAAAACTCCTCTTTCAACAATTTATTTTGGTGGAGGAACTCCTTCAATTTTAGATCCTATT
CAGATCGAACATTTAATAAATCTTTTTAAGGAGAATTACAGAATTGACTATGGTGCTGAAATTACAATGGAAGTTGATCC
AGCTAGTTTTAATGAAGGTGATCTTCATGGCTTTATAAAAGCCGGAATTAATAGATTTAGTCTTGGTGCTCAAAGTTTTA
ATAATCAGATACTTGATCAAGCGGGAAGAAGACATTGTGGTGAAGATGTTGAAAAATCTTGTTCTTGGCTAAAGAGAGCA
CATGATTATGGTCTCATAAAAAGTTGGAGTTTAGATCTGATTCAAAATTTACCAAGTAGTGGTTTTAAAGAATGGCAAGA
AGATTTAGAAAAATCGTTAAAGTTCTGCCCTCCACACATATCAATTTATGATTTAAGTATTGAAAATGGAACAGTTTTTA
AAAAATTAGTTGATTTAGGCAAACTATCATTACCGAATGATGATGAATCTTTTAAAAATAGTGAACTGACACATTTTATT
TTAAAAGCATCAGGTTATTCAAGATATGAAATTTCTAATTATGCTCTCCCTGGTCATCAATCAAGGCATAATAGAGTTTA
TTGGACTGGTCTAGGATGGTGGAGTTTTGGACAAGGCTCTACAAGTTCTCCTTGGGGGGAAAAGTTTACAAGACCAAGAA
TTAGTAAAGACTATAAAAAGTGGGTAGCTGAGCAATGCGAAATTAAATTAGAGACTTCTCTAGAAAATAAAGAAAATATT
TATAAAGAATTAGATGAGAAAATCATGTTAGGAATGAGACTTAAAGAGGGTGTGAATATTTATAAATTGATAAACGAACA
CAATTGGGATAAAAAAAAGTCTGAAATAGCTTTAAAAAAATTATTAAAAGAATGGGAAAGATTCTTAGAAAGTGGTCTTC
TAATTAAAAGAGGTAATAGATTTTTTTTGAGTGATCCAAAAGGTATGGAATTAAGCAATCAAATTCTTGTCTCAATGTTT
AGATGGTGGGACAAAGTTAACTAA

Upstream 100 bases:

>100_bases
CATATATACAATCTACTAGGGTTTATTAATTGAGTAAATAAATATTTTATTTTTTAAACCCCTAACTAGATTTTTTTTAG
CCTAAAAATTTATTTATATT

Downstream 100 bases:

>100_bases
GCCTTTCAGAAGTTACCCACTCTTTAAGTTTTTCACCAAAATATTTTTTCCCATCAACAATTGGTTTACAAAATGGAGGC
TGCTTATCACTTAGGCCTAA

Product: putative oxygen-independent coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNKFPRSAYVHIPFCHRRCFYCDFAVVPLGNNIESLNGYGSNTVKEYLTYLDKEILSIKHKTPLSTIYFGGGTPSILDPI
QIEHLINLFKENYRIDYGAEITMEVDPASFNEGDLHGFIKAGINRFSLGAQSFNNQILDQAGRRHCGEDVEKSCSWLKRA
HDYGLIKSWSLDLIQNLPSSGFKEWQEDLEKSLKFCPPHISIYDLSIENGTVFKKLVDLGKLSLPNDDESFKNSELTHFI
LKASGYSRYEISNYALPGHQSRHNRVYWTGLGWWSFGQGSTSSPWGEKFTRPRISKDYKKWVAEQCEIKLETSLENKENI
YKELDEKIMLGMRLKEGVNIYKLINEHNWDKKKSEIALKKLLKEWERFLESGLLIKRGNRFFLSDPKGMELSNQILVSMF
RWWDKVN

Sequences:

>Translated_407_residues
MNKFPRSAYVHIPFCHRRCFYCDFAVVPLGNNIESLNGYGSNTVKEYLTYLDKEILSIKHKTPLSTIYFGGGTPSILDPI
QIEHLINLFKENYRIDYGAEITMEVDPASFNEGDLHGFIKAGINRFSLGAQSFNNQILDQAGRRHCGEDVEKSCSWLKRA
HDYGLIKSWSLDLIQNLPSSGFKEWQEDLEKSLKFCPPHISIYDLSIENGTVFKKLVDLGKLSLPNDDESFKNSELTHFI
LKASGYSRYEISNYALPGHQSRHNRVYWTGLGWWSFGQGSTSSPWGEKFTRPRISKDYKKWVAEQCEIKLETSLENKENI
YKELDEKIMLGMRLKEGVNIYKLINEHNWDKKKSEIALKKLLKEWERFLESGLLIKRGNRFFLSDPKGMELSNQILVSMF
RWWDKVN
>Mature_407_residues
MNKFPRSAYVHIPFCHRRCFYCDFAVVPLGNNIESLNGYGSNTVKEYLTYLDKEILSIKHKTPLSTIYFGGGTPSILDPI
QIEHLINLFKENYRIDYGAEITMEVDPASFNEGDLHGFIKAGINRFSLGAQSFNNQILDQAGRRHCGEDVEKSCSWLKRA
HDYGLIKSWSLDLIQNLPSSGFKEWQEDLEKSLKFCPPHISIYDLSIENGTVFKKLVDLGKLSLPNDDESFKNSELTHFI
LKASGYSRYEISNYALPGHQSRHNRVYWTGLGWWSFGQGSTSSPWGEKFTRPRISKDYKKWVAEQCEIKLETSLENKENI
YKELDEKIMLGMRLKEGVNIYKLINEHNWDKKKSEIALKKLLKEWERFLESGLLIKRGNRFFLSDPKGMELSNQILVSMF
RWWDKVN

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=273, Percent_Identity=28.9377289377289, Blast_Score=138, Evalue=9e-33,
Organism=Escherichia coli, GI1789325, Length=276, Percent_Identity=34.0579710144928, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI87082341, Length=259, Percent_Identity=29.7297297297297, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 47255; Mature: 47255

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFPRSAYVHIPFCHRRCFYCDFAVVPLGNNIESLNGYGSNTVKEYLTYLDKEILSIKH
CCCCCCCCEEEEEHHHCEEEEEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHC
KTPLSTIYFGGGTPSILDPIQIEHLINLFKENYRIDYGAEITMEVDPASFNEGDLHGFIK
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCCCCHHHHHH
AGINRFSLGAQSFNNQILDQAGRRHCGEDVEKSCSWLKRAHDYGLIKSWSLDLIQNLPSS
HCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHCCCCC
GFKEWQEDLEKSLKFCPPHISIYDLSIENGTVFKKLVDLGKLSLPNDDESFKNSELTHFI
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
LKASGYSRYEISNYALPGHQSRHNRVYWTGLGWWSFGQGSTSSPWGEKFTRPRISKDYKK
EECCCCCEEEECCCCCCCCCCCCCEEEEEEECCEECCCCCCCCCCCHHHCCCCCHHHHHH
WVAEQCEIKLETSLENKENIYKELDEKIMLGMRLKEGVNIYKLINEHNWDKKKSEIALKK
HHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHH
LLKEWERFLESGLLIKRGNRFFLSDPKGMELSNQILVSMFRWWDKVN
HHHHHHHHHHCCCEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKFPRSAYVHIPFCHRRCFYCDFAVVPLGNNIESLNGYGSNTVKEYLTYLDKEILSIKH
CCCCCCCCEEEEEHHHCEEEEEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHC
KTPLSTIYFGGGTPSILDPIQIEHLINLFKENYRIDYGAEITMEVDPASFNEGDLHGFIK
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCCCCHHHHHH
AGINRFSLGAQSFNNQILDQAGRRHCGEDVEKSCSWLKRAHDYGLIKSWSLDLIQNLPSS
HCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHCCCCC
GFKEWQEDLEKSLKFCPPHISIYDLSIENGTVFKKLVDLGKLSLPNDDESFKNSELTHFI
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
LKASGYSRYEISNYALPGHQSRHNRVYWTGLGWWSFGQGSTSSPWGEKFTRPRISKDYKK
EECCCCCEEEECCCCCCCCCCCCCEEEEEEECCEECCCCCCCCCCCHHHCCCCCHHHHHH
WVAEQCEIKLETSLENKENIYKELDEKIMLGMRLKEGVNIYKLINEHNWDKKKSEIALKK
HHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHH
LLKEWERFLESGLLIKRGNRFFLSDPKGMELSNQILVSMFRWWDKVN
HHHHHHHHHHCCCEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]