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The map label for this gene is glcD [H]

Identifier: 123966697

GI number: 123966697

Start: 1300701

End: 1302056

Strand: Reverse

Name: glcD [H]

Synonym: P9515_14641

Alternate gene names: 123966697

Gene position: 1302056-1300701 (Counterclockwise)

Preceding gene: 123966698

Following gene: 123966693

Centisome position: 76.4

GC content: 31.78

Gene sequence:

>1356_bases
ATGTCATCAAGAAAAACAAAATTAATAGAAAAATTTAAAAAAATAGATAATTTAGAGATTATTGAAAGTCATTCGGATGT
AAAAAGACTTTCAAAAGATTTTTATAATTATTCTCCTATTCTTGAAGAGAAATTAGATGGATGTATTGCTGATTTAGTAG
TAAGACCTATTGATAAAAATGCAGTTTTGAAAGTAGCAGAAATTTGTTGGGAACTAAATATTCCTCTCACTTTGAGAGGT
TCAGGGACAGGTAATTATGGACAAGCAGTACCTTTATTTAAGGGAATTGTTATGCAAATGAATTTCCTAAATAAATTAGA
AGAATTTTATCCTGATACAGGTTTTGTAAAGGTACAATCCGGATGTTTAATGGGAGATTTAAATAAACAACTAGAAAGAT
TTGGAAGAGAATTAAGGTTACTGCCCAGTACTTTTAAAACTGCAACTATAGGTGGTTTTATTGCAGGAGGTTCAGGGGGG
ATTGGATCAATTAGATGGGGATTTTTAAGAGATCCCGGAAATGTCATGGGTCTTGAAGCGGTGACAATGAATGAAGAACC
AAAATTATTAAAATTTGATGCTGAAGAATCAGAACCTTTAAATCATGCTTATGGAACGAATGGAATTATTACCTCATTAT
TAATCGCAACAGATATTAAACGTAAGTGGTATTCCTTAGTAATTGACTGCGAAGAGTTATTTAAGACAATAGAAATATTA
AAAACATGCCTTATTGCAGCTATAGACTTGAAACTTGGTGCAATTCTCGAGAAAGGGATTGTTGATAAAATGCCAATTTG
GTTTAAAGGTGAATCTAAAAGCCATAAAATTTTAATTCAATCAACGCTTGGGGGTATAAAAACTATTGAACTAATTTGTA
AAAAATATGGAGTGGAATCTTTTTTACTGGGAGAAGAAGATCAATTATCAAATGGAATCTCTGAGGTCGTATGGAACCAT
ACAACCCTTCACATGAGGGCAAAGGATAAAAATTGGACATATTTACAGATGCTTTTACCTTTAAATAAGGAATTGGAATT
AATTAATTCTTTGAAAGAAAAATGGGGTACGAATATTCTCTGGCATATTGAAGCTGTCTCTCAACAAGGAGTTCCAAGAT
TAGCTGCATTGCCAGTATTAAAATGGCATAGTGAAGAGCAATTGTATCTAATAATTGATCATTGTAAAAAACTTGGAGCA
ATTATTTTTAATCCTCATGTATTAACTGTTGAGGCGGGTGGCTTAGGTGTTATTGATTCTGATCAAGTAAAAGCAAAATT
AAAATTCGATCCTAAAGGGTTGTTAAATCCTGGGAAATTGGAAGGATGGGAAATAAAAGATGACTTTAATCTTTAA

Upstream 100 bases:

>100_bases
GCAGATATTTTTTCAAGTAATTTAAAAAAAGATGTCATTATAAAAGGCGAATTGTATAGCTAATCAATTAGTTTATATTT
AAGTTAGGAAATTATTATTA

Downstream 100 bases:

>100_bases
TAATTTTGATTATTTGCGAATTTAATAAACTCAGAGACTAAAAAAATTGAGCCAGTTAGTACGGGATGACATTTTGGCCA
TGTTCTAAGTTCCAAAAGAT

Product: FAD/FMN-containing dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MSSRKTKLIEKFKKIDNLEIIESHSDVKRLSKDFYNYSPILEEKLDGCIADLVVRPIDKNAVLKVAEICWELNIPLTLRG
SGTGNYGQAVPLFKGIVMQMNFLNKLEEFYPDTGFVKVQSGCLMGDLNKQLERFGRELRLLPSTFKTATIGGFIAGGSGG
IGSIRWGFLRDPGNVMGLEAVTMNEEPKLLKFDAEESEPLNHAYGTNGIITSLLIATDIKRKWYSLVIDCEELFKTIEIL
KTCLIAAIDLKLGAILEKGIVDKMPIWFKGESKSHKILIQSTLGGIKTIELICKKYGVESFLLGEEDQLSNGISEVVWNH
TTLHMRAKDKNWTYLQMLLPLNKELELINSLKEKWGTNILWHIEAVSQQGVPRLAALPVLKWHSEEQLYLIIDHCKKLGA
IIFNPHVLTVEAGGLGVIDSDQVKAKLKFDPKGLLNPGKLEGWEIKDDFNL

Sequences:

>Translated_451_residues
MSSRKTKLIEKFKKIDNLEIIESHSDVKRLSKDFYNYSPILEEKLDGCIADLVVRPIDKNAVLKVAEICWELNIPLTLRG
SGTGNYGQAVPLFKGIVMQMNFLNKLEEFYPDTGFVKVQSGCLMGDLNKQLERFGRELRLLPSTFKTATIGGFIAGGSGG
IGSIRWGFLRDPGNVMGLEAVTMNEEPKLLKFDAEESEPLNHAYGTNGIITSLLIATDIKRKWYSLVIDCEELFKTIEIL
KTCLIAAIDLKLGAILEKGIVDKMPIWFKGESKSHKILIQSTLGGIKTIELICKKYGVESFLLGEEDQLSNGISEVVWNH
TTLHMRAKDKNWTYLQMLLPLNKELELINSLKEKWGTNILWHIEAVSQQGVPRLAALPVLKWHSEEQLYLIIDHCKKLGA
IIFNPHVLTVEAGGLGVIDSDQVKAKLKFDPKGLLNPGKLEGWEIKDDFNL
>Mature_450_residues
SSRKTKLIEKFKKIDNLEIIESHSDVKRLSKDFYNYSPILEEKLDGCIADLVVRPIDKNAVLKVAEICWELNIPLTLRGS
GTGNYGQAVPLFKGIVMQMNFLNKLEEFYPDTGFVKVQSGCLMGDLNKQLERFGRELRLLPSTFKTATIGGFIAGGSGGI
GSIRWGFLRDPGNVMGLEAVTMNEEPKLLKFDAEESEPLNHAYGTNGIITSLLIATDIKRKWYSLVIDCEELFKTIEILK
TCLIAAIDLKLGAILEKGIVDKMPIWFKGESKSHKILIQSTLGGIKTIELICKKYGVESFLLGEEDQLSNGISEVVWNHT
TLHMRAKDKNWTYLQMLLPLNKELELINSLKEKWGTNILWHIEAVSQQGVPRLAALPVLKWHSEEQLYLIIDHCKKLGAI
IFNPHVLTVEAGGLGVIDSDQVKAKLKFDPKGLLNPGKLEGWEIKDDFNL

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=208, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789351, Length=476, Percent_Identity=21.6386554621849, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787977, Length=156, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17534361, Length=200, Percent_Identity=26.5, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320764, Length=200, Percent_Identity=28.5, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320023, Length=199, Percent_Identity=26.6331658291457, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18921117, Length=152, Percent_Identity=27.6315789473684, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24639277, Length=152, Percent_Identity=27.6315789473684, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24639275, Length=152, Percent_Identity=27.6315789473684, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 50623; Mature: 50492

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRKTKLIEKFKKIDNLEIIESHSDVKRLSKDFYNYSPILEEKLDGCIADLVVRPIDKN
CCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCH
AVLKVAEICWELNIPLTLRGSGTGNYGQAVPLFKGIVMQMNFLNKLEEFYPDTGFVKVQS
HHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GCLMGDLNKQLERFGRELRLLPSTFKTATIGGFIAGGSGGIGSIRWGFLRDPGNVMGLEA
CCEEHHHHHHHHHHHHHHEECCCHHHHHCCCCEEECCCCCCCCEEEEEECCCCCEEEEEE
VTMNEEPKLLKFDAEESEPLNHAYGTNGIITSLLIATDIKRKWYSLVIDCEELFKTIEIL
EEECCCCCEEEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHH
KTCLIAAIDLKLGAILEKGIVDKMPIWFKGESKSHKILIQSTLGGIKTIELICKKYGVES
HHHHHHHHHHHHHHHHHHCCHHCCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCC
FLLGEEDQLSNGISEVVWNHTTLHMRAKDKNWTYLQMLLPLNKELELINSLKEKWGTNIL
EECCCHHHHHCCHHHHHCCCEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEE
WHIEAVSQQGVPRLAALPVLKWHSEEQLYLIIDHCKKLGAIIFNPHVLTVEAGGLGVIDS
EEEEECCCCCCCHHHHCCCEEECCCCCEEEEEHHHHHCCCEEECCEEEEEECCCCCCCCC
DQVKAKLKFDPKGLLNPGKLEGWEIKDDFNL
CCCEEEEEECCCCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
SSRKTKLIEKFKKIDNLEIIESHSDVKRLSKDFYNYSPILEEKLDGCIADLVVRPIDKN
CCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCH
AVLKVAEICWELNIPLTLRGSGTGNYGQAVPLFKGIVMQMNFLNKLEEFYPDTGFVKVQS
HHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GCLMGDLNKQLERFGRELRLLPSTFKTATIGGFIAGGSGGIGSIRWGFLRDPGNVMGLEA
CCEEHHHHHHHHHHHHHHEECCCHHHHHCCCCEEECCCCCCCCEEEEEECCCCCEEEEEE
VTMNEEPKLLKFDAEESEPLNHAYGTNGIITSLLIATDIKRKWYSLVIDCEELFKTIEIL
EEECCCCCEEEECCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHH
KTCLIAAIDLKLGAILEKGIVDKMPIWFKGESKSHKILIQSTLGGIKTIELICKKYGVES
HHHHHHHHHHHHHHHHHHCCHHCCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCC
FLLGEEDQLSNGISEVVWNHTTLHMRAKDKNWTYLQMLLPLNKELELINSLKEKWGTNIL
EECCCHHHHHCCHHHHHCCCEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEE
WHIEAVSQQGVPRLAALPVLKWHSEEQLYLIIDHCKKLGAIIFNPHVLTVEAGGLGVIDS
EEEEECCCCCCCHHHHCCCEEECCCCCEEEEEHHHHHCCCEEECCEEEEEECCCCCCCCC
DQVKAKLKFDPKGLLNPGKLEGWEIKDDFNL
CCCEEEEEECCCCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]