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The map label for this gene is surE

Identifier: 123966665

GI number: 123966665

Start: 1270330

End: 1271139

Strand: Direct

Name: surE

Synonym: P9515_14321

Alternate gene names: 123966665

Gene position: 1270330-1271139 (Clockwise)

Preceding gene: 123966662

Following gene: 123966667

Centisome position: 74.54

GC content: 35.56

Gene sequence:

>810_bases
ATGGAATCGTTAAATATATTAATAAGTAATGATGATGGAGTTTTTGCTGAAGGAATAAGAGCATTAGCAAGATCTGCTTT
AAAAAAAGGACATAAAGTAACTGTAGTTTGTCCAGACCAAGAAAGATCGGCAACTGGACATGGCCTCACTTTGCAATCTC
CTTTGAGAGTCGAGAGAGCAGATGAATTATTTGAACCGGGTATTAAAGCGTGGGGATGTTCAGGTACTCCTGCTGATTGT
GTTAAGTTAGCCCTATCAGAATTATTAGACAAAAAGCCTGATTTGATTCTTTCTGGAGTAAATCATGGGCCAAATTTAGG
AACGGATATTTTTTGTTCAGGAACAGTTGCTGCAGCGATGGAAGGGACTTTAGAAAATGTTCCATCTATGGCAATTAGTG
TTGCGAGTTTCAAATGGAAAAACTTTGAATTCGCTAGTGAAATCGCAATGAATATTGCAGAGCAAGCAATCAAGGATAAT
TGGCCAAACGCACTTCTTTTAAATTTGAATATACCGCCATGTGAAAAGAATAAAATAAAGGAATTATCTTGGACAAGATT
ATCAATAAGAAAATATAAAAACCAATTTTCCAAAAGAGAAGACCCAAGAGGAGATGATTATTATTGGTTAGCTGGTGAGG
CTGTTTTAGATCTCAAATCAAAAGGTTATGGGCCTAAGAATTGGCCTAGTGACGTTTCTCAAATAGAAGAAAACAAAATT
TCTCTTACACCTGTAGAAACAGATTTATTTTGGAGAGGCAGTTTAGACGTTTTGCCAAAAATCAATGCTTCATTTATAAA
TGCTTCTTAA

Upstream 100 bases:

>100_bases
CTCTATTTGGCTTAATGATTCAATTTGACTCACTGATATAGTAAAAATAAGTATTTTCTTATCTTACTTAAATATCGTCC
ATAATAAAATGAAATAACCT

Downstream 100 bases:

>100_bases
CAACCATAAAGAGAAGCAAAGTCCAAGGAAATGAGCTGCGATAACTTGCGTATTACTGAGTACTGATAAAATCTCAAGAC
CCGTAATAGGAATATCAGAT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MESLNILISNDDGVFAEGIRALARSALKKGHKVTVVCPDQERSATGHGLTLQSPLRVERADELFEPGIKAWGCSGTPADC
VKLALSELLDKKPDLILSGVNHGPNLGTDIFCSGTVAAAMEGTLENVPSMAISVASFKWKNFEFASEIAMNIAEQAIKDN
WPNALLLNLNIPPCEKNKIKELSWTRLSIRKYKNQFSKREDPRGDDYYWLAGEAVLDLKSKGYGPKNWPSDVSQIEENKI
SLTPVETDLFWRGSLDVLPKINASFINAS

Sequences:

>Translated_269_residues
MESLNILISNDDGVFAEGIRALARSALKKGHKVTVVCPDQERSATGHGLTLQSPLRVERADELFEPGIKAWGCSGTPADC
VKLALSELLDKKPDLILSGVNHGPNLGTDIFCSGTVAAAMEGTLENVPSMAISVASFKWKNFEFASEIAMNIAEQAIKDN
WPNALLLNLNIPPCEKNKIKELSWTRLSIRKYKNQFSKREDPRGDDYYWLAGEAVLDLKSKGYGPKNWPSDVSQIEENKI
SLTPVETDLFWRGSLDVLPKINASFINAS
>Mature_269_residues
MESLNILISNDDGVFAEGIRALARSALKKGHKVTVVCPDQERSATGHGLTLQSPLRVERADELFEPGIKAWGCSGTPADC
VKLALSELLDKKPDLILSGVNHGPNLGTDIFCSGTVAAAMEGTLENVPSMAISVASFKWKNFEFASEIAMNIAEQAIKDN
WPNALLLNLNIPPCEKNKIKELSWTRLSIRKYKNQFSKREDPRGDDYYWLAGEAVLDLKSKGYGPKNWPSDVSQIEENKI
SLTPVETDLFWRGSLDVLPKINASFINAS

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=255, Percent_Identity=36.8627450980392, Blast_Score=158, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_PROM5 (A2BXX8)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001011746.1
- ProteinModelPortal:   A2BXX8
- SMR:   A2BXX8
- STRING:   A2BXX8
- GeneID:   4718718
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_14321
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- ProtClustDB:   PRK00346
- BioCyc:   PMAR167542:P9515ORF_1496-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 29605; Mature: 29605

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLNILISNDDGVFAEGIRALARSALKKGHKVTVVCPDQERSATGHGLTLQSPLRVERA
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCHHHH
DELFEPGIKAWGCSGTPADCVKLALSELLDKKPDLILSGVNHGPNLGTDIFCSGTVAAAM
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEECCHHHHHH
EGTLENVPSMAISVASFKWKNFEFASEIAMNIAEQAIKDNWPNALLLNLNIPPCEKNKIK
HHHHHHCCHHHEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHH
ELSWTRLSIRKYKNQFSKREDPRGDDYYWLAGEAVLDLKSKGYGPKNWPSDVSQIEENKI
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEHHHCCCCCCCCCHHHHHHHHCCE
SLTPVETDLFWRGSLDVLPKINASFINAS
EEEEECCCEEECCCCCCCCCCCCEEECCC
>Mature Secondary Structure
MESLNILISNDDGVFAEGIRALARSALKKGHKVTVVCPDQERSATGHGLTLQSPLRVERA
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCHHHH
DELFEPGIKAWGCSGTPADCVKLALSELLDKKPDLILSGVNHGPNLGTDIFCSGTVAAAM
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEECCHHHHHH
EGTLENVPSMAISVASFKWKNFEFASEIAMNIAEQAIKDNWPNALLLNLNIPPCEKNKIK
HHHHHHCCHHHEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHH
ELSWTRLSIRKYKNQFSKREDPRGDDYYWLAGEAVLDLKSKGYGPKNWPSDVSQIEENKI
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEHHHCCCCCCCCCHHHHHHHHCCE
SLTPVETDLFWRGSLDVLPKINASFINAS
EEEEECCCEEECCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA