Click here to switch to the map view.

The map label for this gene is glyQ

Identifier: 123966568

GI number: 123966568

Start: 1174556

End: 1175425

Strand: Reverse

Name: glyQ

Synonym: P9515_13351

Alternate gene names: 123966568

Gene position: 1175425-1174556 (Counterclockwise)

Preceding gene: 123966569

Following gene: 123966567

Centisome position: 68.97

GC content: 35.63

Gene sequence:

>870_bases
ATGTTTTTTCAAGATATAATTCAAAATTTAAATAAATTCTGGTCTGAAGAAGGTTGTTTGATTATGCAACCTTATGACAC
TGAAAAAGGTGCAGGAACTATGAACCCGCATACTTTCCTTAGAGCAATTGGGCCCGAGCCTTGGAGTGTTGCGTATGCTG
AGCCATGTAGAAGACCTACTGATGGAAGATTTGGAGATAACCCAAACAGGGCTCAACATTATTTTCAATATCAAGTAATC
ATTAAACCATCTCCTGATAGAATTCAAGAGAAATATTTATCTTCTTTAGAGTTTTTAGGTATTAACCCTAAGGAACACGA
CATAAGATTTGTAGAAGATAATTGGGAGTCCCCTACCCTTGGCGCATGGGGAGTGGGCTGGGAAGTCTGGTTGGATGGGA
TGGAGGTAACACAATTTACTTATTTTCAACAATGTGGGGGGGTTGACTGTAATCCAATTCCCATTGAGATAACTTACGGA
CTAGAGAGAATTGCGACGTTTTTGCAAGATAAAGAAAGTATTTGGGATTTAGATTGGAATAAAGATTTCAACTACAGCGA
TATTTGGCTTCAATTTGAAAAAAATCAATGCGAATTTAACTTTAGAGCATCAAATCCCGAAAACATGAGGAAACTATTTT
CAATATATCAAGAAGAAGCTGTATCTCTTCTTGATAAAAAACTTACTTTTCCTGCTCTGGATTTTGTATTAAAATGCAGT
CATTGCTTTAATTTGCTTGATGCTAGAGGAGTGATTTCAGTTACTGATCGTGCGCAATATATTGAAAAGATTCGAAAATT
AGCTAGAGAAGTGGCATCCTCTTGGATAATTGAAAGAGAGTCTTTGAAATTTCCTTTATTAAAAAAATAA

Upstream 100 bases:

>100_bases
GAAACAGAAATAAGAATTTTCAAAAAATTTATTTTTTCTTTTAAGTGGTTTTGTTATTATATTCTTTGGCATTGATGTAA
CCTAGACAATTTTTAATTTA

Downstream 100 bases:

>100_bases
TTTGATTAGAAAGCATCTGAAATAAGCTCCGTATCATTTGCTACATAGAAGTGAATCTATTAATCCTACTTAAAAATGTT
ACCCTCGATACAATTACTAT

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MFFQDIIQNLNKFWSEEGCLIMQPYDTEKGAGTMNPHTFLRAIGPEPWSVAYAEPCRRPTDGRFGDNPNRAQHYFQYQVI
IKPSPDRIQEKYLSSLEFLGINPKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGVDCNPIPIEITYG
LERIATFLQDKESIWDLDWNKDFNYSDIWLQFEKNQCEFNFRASNPENMRKLFSIYQEEAVSLLDKKLTFPALDFVLKCS
HCFNLLDARGVISVTDRAQYIEKIRKLAREVASSWIIERESLKFPLLKK

Sequences:

>Translated_289_residues
MFFQDIIQNLNKFWSEEGCLIMQPYDTEKGAGTMNPHTFLRAIGPEPWSVAYAEPCRRPTDGRFGDNPNRAQHYFQYQVI
IKPSPDRIQEKYLSSLEFLGINPKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGVDCNPIPIEITYG
LERIATFLQDKESIWDLDWNKDFNYSDIWLQFEKNQCEFNFRASNPENMRKLFSIYQEEAVSLLDKKLTFPALDFVLKCS
HCFNLLDARGVISVTDRAQYIEKIRKLAREVASSWIIERESLKFPLLKK
>Mature_289_residues
MFFQDIIQNLNKFWSEEGCLIMQPYDTEKGAGTMNPHTFLRAIGPEPWSVAYAEPCRRPTDGRFGDNPNRAQHYFQYQVI
IKPSPDRIQEKYLSSLEFLGINPKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGVDCNPIPIEITYG
LERIATFLQDKESIWDLDWNKDFNYSDIWLQFEKNQCEFNFRASNPENMRKLFSIYQEEAVSLLDKKLTFPALDFVLKCS
HCFNLLDARGVISVTDRAQYIEKIRKLAREVASSWIIERESLKFPLLKK

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=293, Percent_Identity=54.2662116040956, Blast_Score=339, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_PROM5 (A2BXN1)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001011649.1
- ProteinModelPortal:   A2BXN1
- SMR:   A2BXN1
- STRING:   A2BXN1
- GeneID:   4718856
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_13351
- eggNOG:   COG0752
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BioCyc:   PMAR167542:P9515ORF_1395-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 33900; Mature: 33900

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFQDIIQNLNKFWSEEGCLIMQPYDTEKGAGTMNPHTFLRAIGPEPWSVAYAEPCRRPT
CCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCEECHHHHCCCCC
DGRFGDNPNRAQHYFQYQVIIKPSPDRIQEKYLSSLEFLGINPKEHDIRFVEDNWESPTL
CCCCCCCCCHHHEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCC
GAWGVGWEVWLDGMEVTQFTYFQQCGGVDCNPIPIEITYGLERIATFLQDKESIWDLDWN
CCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCHHHHCCCCCC
KDFNYSDIWLQFEKNQCEFNFRASNPENMRKLFSIYQEEAVSLLDKKLTFPALDFVLKCS
CCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
HCFNLLDARGVISVTDRAQYIEKIRKLAREVASSWIIERESLKFPLLKK
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFFQDIIQNLNKFWSEEGCLIMQPYDTEKGAGTMNPHTFLRAIGPEPWSVAYAEPCRRPT
CCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCEECHHHHCCCCC
DGRFGDNPNRAQHYFQYQVIIKPSPDRIQEKYLSSLEFLGINPKEHDIRFVEDNWESPTL
CCCCCCCCCHHHEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCC
GAWGVGWEVWLDGMEVTQFTYFQQCGGVDCNPIPIEITYGLERIATFLQDKESIWDLDWN
CCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCHHHHCCCCCC
KDFNYSDIWLQFEKNQCEFNFRASNPENMRKLFSIYQEEAVSLLDKKLTFPALDFVLKCS
CCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
HCFNLLDARGVISVTDRAQYIEKIRKLAREVASSWIIERESLKFPLLKK
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA