Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 123966548

GI number: 123966548

Start: 1156058

End: 1157434

Strand: Direct

Name: trxB [H]

Synonym: P9515_13151

Alternate gene names: 123966548

Gene position: 1156058-1157434 (Clockwise)

Preceding gene: 123966547

Following gene: 123966553

Centisome position: 67.84

GC content: 36.46

Gene sequence:

>1377_bases
ATGGAAATGATAAAAAAAGAAGAAAACATTGAAAATTTAGTAATAATAGGTTCTGGTCCTGCGGGTTATACAGCAGCAAT
ATACGCTGCTCGTGCAAATCTACAACCTCTCTTGGTTACTGGGTTTAATTCTGGAGGGATTCCCGGGGGGCAATTAATGA
CAACTACTTTTGTTGAAAACTTTCCCGGTTTTCCCGATGGGGTATTAGGACCTGAATTAATGGACTTAATGAAAGCTCAA
GCTGAAAGATGGGGGACTAATTTATATGAGAGTGATGTAATTTCAATTGATACAAGTAAACGTCCTTTTGAGCTGAAAAC
CCTAGAAGGGATTATTAAAACAAATTCAATTATTATTGCAACTGGAGCAAGTGCCAATAGGTTGGGGGTGATAAATGAAG
ATAAATTTTGGAGCAAAGGCATAAGTGCGTGCGCAATTTGTGACGGGGCAACGCCACAATTTAGAAATGAAGAACTAGCA
GTTATTGGAGGGGGAGATTCTGCATGTGAAGAAGCGGCATATCTTACAAAATATGGCAGCAAAGTTCATTTACTAGTTAG
ATCTGAAAAATTAAGAGCTAGTGCCGCAATGATAGATAGAGTAAAAGGCAACTCAAAGATCGAAATTCATTGGAACACAA
AAGTAGAAAAAGCAATTGGGACTGATTGGCTTGACAAGATTGAAGCTATTAACACAGAAAAAGGCTACGTCGAGATTAAA
GTTAAAGGACTTTTTTATGCTATTGGACACACTCCTAATACAAAGTTTTTGGACAATAAAATTGAATTAGACAAAAAAGG
ATATATTGCTTGTAAATCAGGTAGACCAGAAACTTCTATAGATGGAATATATGCAGCTGGAGATGTAGTAGATTCTGAAT
GGCGACAAGGAGTTACAGCTGCTGGGACAGGTTGTATGGCAGCATTGGCTGCTGAGCGATGGTTAGCAGAGAAAAATTTA
TCAAAAATAATTATTAGAGAAAAAGCCGAACCAGAAAAAACATTGCCTTCTTCGAGTTTTAATGAAGAGGAGACAGATGA
AAACACTTTCGATTTAAACTCTAAATGGCAAAAAGGTAGTTATGCACTTAGGAAACTTTATCATGAGAGCAATAAACCAA
TTCTAGTTATTTTCAGCTCTCCAAGCTGTGGACCTTGTCATGTTTTAAAACCGCAACTTAAAAGAGTGATCAATGAATTT
GATGGGGCTGTTCAGGGTATAGAAATTGATATTGATAAAGATCAAGAAATTGCTAAACAAGCCGGAATAAATGGAACTCC
GACAATACAGCTATTTAAAGAAAAATTACTTAAAAAACAGTGGCAAGGAGTTAAGCAACGTAGTGAATTCAAAGAAGCAA
TACAAAACATCATCTAA

Upstream 100 bases:

>100_bases
GAATTATTAGATCAAAAAATAAATGAGAAATTAATCGAGTGAAATCCGACCTTCATAAATAGAGACTATTGATTAACATT
GTAAATATTTGATATTTAAA

Downstream 100 bases:

>100_bases
GAAATTTTAATTATTTATTTCCTTCTTACATTATTTTTAGAATTTCCGGATCTCGGGCCTCCTCCACCTGCATTTCTCTC
TCGATAAGTAATCCTACCTC

Product: putative thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MEMIKKEENIENLVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENFPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVISIDTSKRPFELKTLEGIIKTNSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRNEELA
VIGGGDSACEEAAYLTKYGSKVHLLVRSEKLRASAAMIDRVKGNSKIEIHWNTKVEKAIGTDWLDKIEAINTEKGYVEIK
VKGLFYAIGHTPNTKFLDNKIELDKKGYIACKSGRPETSIDGIYAAGDVVDSEWRQGVTAAGTGCMAALAAERWLAEKNL
SKIIIREKAEPEKTLPSSSFNEEETDENTFDLNSKWQKGSYALRKLYHESNKPILVIFSSPSCGPCHVLKPQLKRVINEF
DGAVQGIEIDIDKDQEIAKQAGINGTPTIQLFKEKLLKKQWQGVKQRSEFKEAIQNII

Sequences:

>Translated_458_residues
MEMIKKEENIENLVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENFPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVISIDTSKRPFELKTLEGIIKTNSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRNEELA
VIGGGDSACEEAAYLTKYGSKVHLLVRSEKLRASAAMIDRVKGNSKIEIHWNTKVEKAIGTDWLDKIEAINTEKGYVEIK
VKGLFYAIGHTPNTKFLDNKIELDKKGYIACKSGRPETSIDGIYAAGDVVDSEWRQGVTAAGTGCMAALAAERWLAEKNL
SKIIIREKAEPEKTLPSSSFNEEETDENTFDLNSKWQKGSYALRKLYHESNKPILVIFSSPSCGPCHVLKPQLKRVINEF
DGAVQGIEIDIDKDQEIAKQAGINGTPTIQLFKEKLLKKQWQGVKQRSEFKEAIQNII
>Mature_458_residues
MEMIKKEENIENLVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENFPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVISIDTSKRPFELKTLEGIIKTNSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRNEELA
VIGGGDSACEEAAYLTKYGSKVHLLVRSEKLRASAAMIDRVKGNSKIEIHWNTKVEKAIGTDWLDKIEAINTEKGYVEIK
VKGLFYAIGHTPNTKFLDNKIELDKKGYIACKSGRPETSIDGIYAAGDVVDSEWRQGVTAAGTGCMAALAAERWLAEKNL
SKIIIREKAEPEKTLPSSSFNEEETDENTFDLNSKWQKGSYALRKLYHESNKPILVIFSSPSCGPCHVLKPQLKRVINEF
DGAVQGIEIDIDKDQEIAKQAGINGTPTIQLFKEKLLKKQWQGVKQRSEFKEAIQNII

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=314, Percent_Identity=45.859872611465, Blast_Score=261, Evalue=6e-71,
Organism=Escherichia coli, GI87081763, Length=316, Percent_Identity=30.0632911392405, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320560, Length=310, Percent_Identity=53.2258064516129, Blast_Score=319, Evalue=5e-88,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=49.8402555910543, Blast_Score=302, Evalue=8e-83,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 50341; Mature: 50341

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMIKKEENIENLVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVEN
CCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEHHHHHHH
FPGFPDGVLGPELMDLMKAQAERWGTNLYESDVISIDTSKRPFELKTLEGIIKTNSIIIA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEHHHHHHHHCCCCEEEE
TGASANRLGVINEDKFWSKGISACAICDGATPQFRNEELAVIGGGDSACEEAAYLTKYGS
ECCCCCEEEECCCCHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
KVHLLVRSEKLRASAAMIDRVKGNSKIEIHWNTKVEKAIGTDWLDKIEAINTEKGYVEIK
EEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCHHHHHHHHCCCCCCEEEEE
VKGLFYAIGHTPNTKFLDNKIELDKKGYIACKSGRPETSIDGIYAAGDVVDSEWRQGVTA
EEEEEEEECCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCEEEECCCCHHHHHCCCCC
AGTGCMAALAAERWLAEKNLSKIIIREKAEPEKTLPSSSFNEEETDENTFDLNSKWQKGS
CCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
YALRKLYHESNKPILVIFSSPSCGPCHVLKPQLKRVINEFDGAVQGIEIDIDKDQEIAKQ
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHH
AGINGTPTIQLFKEKLLKKQWQGVKQRSEFKEAIQNII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEMIKKEENIENLVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVEN
CCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEHHHHHHH
FPGFPDGVLGPELMDLMKAQAERWGTNLYESDVISIDTSKRPFELKTLEGIIKTNSIIIA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEHHHHHHHHCCCCEEEE
TGASANRLGVINEDKFWSKGISACAICDGATPQFRNEELAVIGGGDSACEEAAYLTKYGS
ECCCCCEEEECCCCHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
KVHLLVRSEKLRASAAMIDRVKGNSKIEIHWNTKVEKAIGTDWLDKIEAINTEKGYVEIK
EEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCHHHHHHHHCCCCCCEEEEE
VKGLFYAIGHTPNTKFLDNKIELDKKGYIACKSGRPETSIDGIYAAGDVVDSEWRQGVTA
EEEEEEEECCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCEEEECCCCHHHHHCCCCC
AGTGCMAALAAERWLAEKNLSKIIIREKAEPEKTLPSSSFNEEETDENTFDLNSKWQKGS
CCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
YALRKLYHESNKPILVIFSSPSCGPCHVLKPQLKRVINEFDGAVQGIEIDIDKDQEIAKQ
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHH
AGINGTPTIQLFKEKLLKKQWQGVKQRSEFKEAIQNII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]