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The map label for this gene is aapM [H]

Identifier: 123966463

GI number: 123966463

Start: 1085354

End: 1086373

Strand: Reverse

Name: aapM [H]

Synonym: P9515_12301

Alternate gene names: 123966463

Gene position: 1086373-1085354 (Counterclockwise)

Preceding gene: 123966464

Following gene: 123966462

Centisome position: 63.75

GC content: 30.2

Gene sequence:

>1020_bases
ATGAATAATTTAAATACACATTCATTTAAAAAACTTAAAAAATTTTTAAAATCAAAACCAAAATATAATTTTTTCAATTT
TATATTTTTTGTGTTTTCAATTTTATTGACTTTAAAAATTTCAACTTGGATTTTTTTTAAATCAAATTGGAAAGTTGTAA
CATCAAATCTTAATTTATATGCATTTGGGAGCTTTCCAATTAATGAGCAATGGAGGCCTACTCTTTGGTTCTTAAGTCTT
TTATCTATTACCTTTATTACTGTTTATGGCCCAAAATGGAATTGGCTCCGTAAAAATTTAATTTTTGGATGGATGGGAAC
AGTACCTTTAGGGATTTACTTGCTAAATGGTGGTTTGGGTTTAGTTCCTGTAATGACTCGTCATTGGGGTGGGTTAACAC
TAACAATTCTTATAACTTCTTGTAGTATTCTTTTTTCTTTGCCAATTGGAATTGTATTAGCTCTTTGCAGAAGAAGTTCA
ATGTTTTTAATTCAAAAACTAAGTTCTTTTTATATTGATGTAATGAGAGCTGTTCCTCTTATCGCCGTACTTTTTTTTGG
ACAATTGTTAATACCTTTATTTCTACCTGTCGGTCTAGAAATAGAACGTGTCTGGAGGGCAATAATAGCATTTACTTTAT
TTGTTTCAGCATATATAGCTGAAGATATTCGCGGGGGATTACAATCAATACCTAATAATCAAATAGAAGCTGCTAAAAGT
CTTGGCTTGAACAAATATCAAGTCAATATATTTATTCTTATTCCTCAAGCCTTAAGAGTTGCATTGCCAGCTATTACAAA
CCAGTTAATTGGGCTTTTTCAAAATACATCTTTAATGTCTATCCTAGGTTTAATGGAATTACTTGGGGTAAGTAGAAGTA
TTCTTGCCAATCCAGAATTCATAGGACAATATATTGAAGTATATATTTGGTTAGCTTCCGTATACTGGTTATTTTGCACA
GTTATGGCATTTGTTTCAAAAAAGCTCGAGCAGAGAATGACAATTAACAAAGGATTTTAA

Upstream 100 bases:

>100_bases
ATAATTTTACTTTTCAGTTTTTTAATCCTTAATTTATTAATAACAAAAGTAATGGAAATTATTGATAAATCAATAATGAA
AAAAAGGATATAAATTATTA

Downstream 100 bases:

>100_bases
TTTTATACTTATGAAGCCAATACTAAGTGCTAAAAATCTCACTAAATCTTATGCTAAAGGTACTCTTGCTCTTAATAAAG
TTTCATTTACCTTAGATCAA

Product: ABC transporter for amino acids, membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNNLNTHSFKKLKKFLKSKPKYNFFNFIFFVFSILLTLKISTWIFFKSNWKVVTSNLNLYAFGSFPINEQWRPTLWFLSL
LSITFITVYGPKWNWLRKNLIFGWMGTVPLGIYLLNGGLGLVPVMTRHWGGLTLTILITSCSILFSLPIGIVLALCRRSS
MFLIQKLSSFYIDVMRAVPLIAVLFFGQLLIPLFLPVGLEIERVWRAIIAFTLFVSAYIAEDIRGGLQSIPNNQIEAAKS
LGLNKYQVNIFILIPQALRVALPAITNQLIGLFQNTSLMSILGLMELLGVSRSILANPEFIGQYIEVYIWLASVYWLFCT
VMAFVSKKLEQRMTINKGF

Sequences:

>Translated_339_residues
MNNLNTHSFKKLKKFLKSKPKYNFFNFIFFVFSILLTLKISTWIFFKSNWKVVTSNLNLYAFGSFPINEQWRPTLWFLSL
LSITFITVYGPKWNWLRKNLIFGWMGTVPLGIYLLNGGLGLVPVMTRHWGGLTLTILITSCSILFSLPIGIVLALCRRSS
MFLIQKLSSFYIDVMRAVPLIAVLFFGQLLIPLFLPVGLEIERVWRAIIAFTLFVSAYIAEDIRGGLQSIPNNQIEAAKS
LGLNKYQVNIFILIPQALRVALPAITNQLIGLFQNTSLMSILGLMELLGVSRSILANPEFIGQYIEVYIWLASVYWLFCT
VMAFVSKKLEQRMTINKGF
>Mature_339_residues
MNNLNTHSFKKLKKFLKSKPKYNFFNFIFFVFSILLTLKISTWIFFKSNWKVVTSNLNLYAFGSFPINEQWRPTLWFLSL
LSITFITVYGPKWNWLRKNLIFGWMGTVPLGIYLLNGGLGLVPVMTRHWGGLTLTILITSCSILFSLPIGIVLALCRRSS
MFLIQKLSSFYIDVMRAVPLIAVLFFGQLLIPLFLPVGLEIERVWRAIIAFTLFVSAYIAEDIRGGLQSIPNNQIEAAKS
LGLNKYQVNIFILIPQALRVALPAITNQLIGLFQNTSLMSILGLMELLGVSRSILANPEFIGQYIEVYIWLASVYWLFCT
VMAFVSKKLEQRMTINKGF

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=294, Percent_Identity=37.7551020408163, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI1788226, Length=206, Percent_Identity=33.0097087378641, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1786873, Length=236, Percent_Identity=31.7796610169492, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786874, Length=195, Percent_Identity=27.1794871794872, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787030, Length=207, Percent_Identity=29.4685990338164, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994930, Length=127, Percent_Identity=33.8582677165354, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787087, Length=222, Percent_Identity=24.7747747747748, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788645, Length=173, Percent_Identity=29.4797687861272, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788646, Length=171, Percent_Identity=29.2397660818713, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38740; Mature: 38740

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLNTHSFKKLKKFLKSKPKYNFFNFIFFVFSILLTLKISTWIFFKSNWKVVTSNLNLY
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCEEE
AFGSFPINEQWRPTLWFLSLLSITFITVYGPKWNWLRKNLIFGWMGTVPLGIYLLNGGLG
EEECCCCCCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LVPVMTRHWGGLTLTILITSCSILFSLPIGIVLALCRRSSMFLIQKLSSFYIDVMRAVPL
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IAVLFFGQLLIPLFLPVGLEIERVWRAIIAFTLFVSAYIAEDIRGGLQSIPNNQIEAAKS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LGLNKYQVNIFILIPQALRVALPAITNQLIGLFQNTSLMSILGLMELLGVSRSILANPEF
CCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCHHH
IGQYIEVYIWLASVYWLFCTVMAFVSKKLEQRMTINKGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNNLNTHSFKKLKKFLKSKPKYNFFNFIFFVFSILLTLKISTWIFFKSNWKVVTSNLNLY
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCEEE
AFGSFPINEQWRPTLWFLSLLSITFITVYGPKWNWLRKNLIFGWMGTVPLGIYLLNGGLG
EEECCCCCCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LVPVMTRHWGGLTLTILITSCSILFSLPIGIVLALCRRSSMFLIQKLSSFYIDVMRAVPL
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IAVLFFGQLLIPLFLPVGLEIERVWRAIIAFTLFVSAYIAEDIRGGLQSIPNNQIEAAKS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LGLNKYQVNIFILIPQALRVALPAITNQLIGLFQNTSLMSILGLMELLGVSRSILANPEF
CCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCHHH
IGQYIEVYIWLASVYWLFCTVMAFVSKKLEQRMTINKGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]