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The map label for this gene is sasA [H]

Identifier: 123966400

GI number: 123966400

Start: 1021548

End: 1022666

Strand: Reverse

Name: sasA [H]

Synonym: P9515_11671

Alternate gene names: 123966400

Gene position: 1022666-1021548 (Counterclockwise)

Preceding gene: 123966403

Following gene: 123966398

Centisome position: 60.01

GC content: 33.96

Gene sequence:

>1119_bases
TTGAATGAAAAAAAAGAACTAAAACTAATACTAGTAGCTGCTAGAAATCACCTTTCTAGAGTTGATTTGAAATTATTATT
GTCTTATTTAGAATCAGATGATTGTGAATTTGATATTTCTCTTCAAATTTCTGAACCAACGGAACAACCGGAATTACTTG
AGTTGCATCGATTGGTTGCTATTCCAGCTCTTATAAAAGTTTCACCGGGTCCAAAGCAAATATTTGCTGGGAGTAATATT
TTTGTTCAATTGCAGACTTGGTTGCCTAGATGGAAGCAAGAAGGGGTAACTAATAATTTGGGTATTAATCTTCAACCTTC
CAAAATAGATTCAATTAGAACACAAAAAGAATTTCTCCTTGAGGAGGAATTGTTGGTCCTAAGACAAGAAAATGAGACGC
TTACAAAAAGAATCGAATCGCAAGAAAGACTTTTAAGGATGGTTGCACATGAATTGAGAACACCTTTAACTGCTGCCACT
CTGGCTATTCAAAGTCAAAAATTAGGTCAAATTGATATAAAAAAATTACAAGATGTTATTAAACGACGCTTAGAAGAAAT
TGAACTTTTATCTCAAGATCTTCTAGAAGTTGGAACCACTAAATGGGAAGCACTTTTTAATCCTCAAAAAATTGACTTAG
GAAATATAAGTGCCGAAGCAATACTTGAATTAGAAAAATTTTGGAGATTAAGAAGAATTGAAATTGATACTGATATTCCT
TCCGATCTCCCGTGTGTATTTGCAGATCAAAGAAGAATGAGACAGGTATTTTTAAATTTAATTGAAAATGCTCTTAAATT
TTCAGAAGATTCTGGATTGATAAAAATTACAATGATTCATAAAACAAATCAATGGGTAGAAATAACAATTTGTGACAAAG
GAGCTGGGATTCCTTTAAGTGAACAAAAAAGAATATTTCTTGATAGAGTGAGGCTACCACAGACATCTGAGGGAACCTCT
GGATTTGGTATTGGCTTATCTGTATGCAGAAGAATTGTTGAAGTTCATGGAGGAAGAATATGGGTAGTATCAGAAGTTGG
GGAAGGTTCGTGCTTTCATTTTACGGTCCCAGTGTGGCAAGGCCAAAACAAAGATCAACAACACTTGACGAAAGGATAG

Upstream 100 bases:

>100_bases
ATAGCATCTATTTATTTCATAGCTTATCTGTAAAATAAATATAAATATCTTAATGTGTTTATAAGCAATAAAAGCTTTTC
AACACTTCAGGGGAAATGAT

Downstream 100 bases:

>100_bases
CTTTACTCCTAATTTTTTATAAGCTATACAGCTATTTCCTTGGCCCCATCGTCTAGAGGCCTAGGACACCTCCCTTTCAC
GGAGGCGACAGGGGTTCGAA

Product: adaptive-response sensory kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MNEKKELKLILVAARNHLSRVDLKLLLSYLESDDCEFDISLQISEPTEQPELLELHRLVAIPALIKVSPGPKQIFAGSNI
FVQLQTWLPRWKQEGVTNNLGINLQPSKIDSIRTQKEFLLEEELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAIQSQKLGQIDIKKLQDVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEAILELEKFWRLRRIEIDTDIP
SDLPCVFADQRRMRQVFLNLIENALKFSEDSGLIKITMIHKTNQWVEITICDKGAGIPLSEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVEVHGGRIWVVSEVGEGSCFHFTVPVWQGQNKDQQHLTKG

Sequences:

>Translated_372_residues
MNEKKELKLILVAARNHLSRVDLKLLLSYLESDDCEFDISLQISEPTEQPELLELHRLVAIPALIKVSPGPKQIFAGSNI
FVQLQTWLPRWKQEGVTNNLGINLQPSKIDSIRTQKEFLLEEELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAIQSQKLGQIDIKKLQDVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEAILELEKFWRLRRIEIDTDIP
SDLPCVFADQRRMRQVFLNLIENALKFSEDSGLIKITMIHKTNQWVEITICDKGAGIPLSEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVEVHGGRIWVVSEVGEGSCFHFTVPVWQGQNKDQQHLTKG
>Mature_372_residues
MNEKKELKLILVAARNHLSRVDLKLLLSYLESDDCEFDISLQISEPTEQPELLELHRLVAIPALIKVSPGPKQIFAGSNI
FVQLQTWLPRWKQEGVTNNLGINLQPSKIDSIRTQKEFLLEEELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAIQSQKLGQIDIKKLQDVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEAILELEKFWRLRRIEIDTDIP
SDLPCVFADQRRMRQVFLNLIENALKFSEDSGLIKITMIHKTNQWVEITICDKGAGIPLSEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVEVHGGRIWVVSEVGEGSCFHFTVPVWQGQNKDQQHLTKG

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=28.9256198347107, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=30.5555555555556, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=27.3913043478261, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=29.4820717131474, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=253, Percent_Identity=27.6679841897233, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=27.4436090225564, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=25.6521739130435, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=258, Percent_Identity=26.3565891472868, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=29.0598290598291, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=238, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787894, Length=245, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=23.6842105263158, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 42589; Mature: 42589

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50109 HIS_KIN ; PS00287 CYSTATIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKKELKLILVAARNHLSRVDLKLLLSYLESDDCEFDISLQISEPTEQPELLELHRLVA
CCCCHHEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
IPALIKVSPGPKQIFAGSNIFVQLQTWLPRWKQEGVTNNLGINLQPSKIDSIRTQKEFLL
HHHHEEECCCCHHEECCCCEEEEEHHHCCHHHHCCCCCCCCCEECCHHHHHHHHHHHHHH
EEELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAATLAIQSQKLGQIDIKKLQDVI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
KRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEAILELEKFWRLRRIEIDTDIP
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCCHHHHHHHHHHHHHEEEEECCCCC
SDLPCVFADQRRMRQVFLNLIENALKFSEDSGLIKITMIHKTNQWVEITICDKGAGIPLS
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCC
EQKRIFLDRVRLPQTSEGTSGFGIGLSVCRRIVEVHGGRIWVVSEVGEGSCFHFTVPVWQ
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEEC
GQNKDQQHLTKG
CCCCCHHHCCCC
>Mature Secondary Structure
MNEKKELKLILVAARNHLSRVDLKLLLSYLESDDCEFDISLQISEPTEQPELLELHRLVA
CCCCHHEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
IPALIKVSPGPKQIFAGSNIFVQLQTWLPRWKQEGVTNNLGINLQPSKIDSIRTQKEFLL
HHHHEEECCCCHHEECCCCEEEEEHHHCCHHHHCCCCCCCCCEECCHHHHHHHHHHHHHH
EEELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAATLAIQSQKLGQIDIKKLQDVI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
KRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEAILELEKFWRLRRIEIDTDIP
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCCHHHHHHHHHHHHHEEEEECCCCC
SDLPCVFADQRRMRQVFLNLIENALKFSEDSGLIKITMIHKTNQWVEITICDKGAGIPLS
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCC
EQKRIFLDRVRLPQTSEGTSGFGIGLSVCRRIVEVHGGRIWVVSEVGEGSCFHFTVPVWQ
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEEC
GQNKDQQHLTKG
CCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA