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The map label for this gene is cobU [H]

Identifier: 123966177

GI number: 123966177

Start: 837188

End: 837736

Strand: Reverse

Name: cobU [H]

Synonym: P9515_09441

Alternate gene names: 123966177

Gene position: 837736-837188 (Counterclockwise)

Preceding gene: 123966178

Following gene: 123966176

Centisome position: 49.16

GC content: 27.87

Gene sequence:

>549_bases
ATGGAAAATCATGGTAATAATTTTGCAAAAGTAATATTTATAACTGGGGGAACAAAGAGCGGTAAAAGCGAATTTGCAGA
ATATTTAGGTAGAAAATTACCAAAAATAACTTATATAGCCTTATCTGAGTCAAGACCAGACGATTTAAATTGGCAAAAAA
AAATTCTTCAGCATCGTAAAAGAAGGCCTAAAAATTGGGCGTTAATAGAAACAAATAATCTTGTAAATGTATTAAAAAAA
GACAAAGGTCCAATATTAATTGACTCTATAGGAGGCTTTATAATGGAGAGTATCTATAAAAATGATGAAGAATGGGAAAA
TCAAATACATTTGCTTTTAAATCTTTTAAAAAACAGAATAAAAACAACATTAATTGTTGGAGAACAAGTTGGTTGGAGTT
TAGTTTCAGAATACGAAATTGGTAATAAATATATAGAAAGGCTTGGAGATCTTCAAAAAAGAATAACTAGAATTTCAGAA
GAGAATTGGCTAACCATAAATGGTAGAGCAATAAAATTAGATAAAATTAGTATTGAAATACCTTTTTAG

Upstream 100 bases:

>100_bases
GAGTTCTACAGCTACTTATATAGTTATTGGCCTCTTAGTTGCAGCTACAATAATACCTCTTGCAACATGGTGGTTTTTCT
CAAAATAAGTTTTTTTAAAG

Downstream 100 bases:

>100_bases
TAATTGGAAATCTCACTTTTTGAACCGCGGATTCCTCAAAATACTGGTAGTATCGCTAGAACGTGTGCTGCTTTTGACAT
AACATTAAATCTTATAGAGC

Product: putative cobinamide kinase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MENHGNNFAKVIFITGGTKSGKSEFAEYLGRKLPKITYIALSESRPDDLNWQKKILQHRKRRPKNWALIETNNLVNVLKK
DKGPILIDSIGGFIMESIYKNDEEWENQIHLLLNLLKNRIKTTLIVGEQVGWSLVSEYEIGNKYIERLGDLQKRITRISE
ENWLTINGRAIKLDKISIEIPF

Sequences:

>Translated_182_residues
MENHGNNFAKVIFITGGTKSGKSEFAEYLGRKLPKITYIALSESRPDDLNWQKKILQHRKRRPKNWALIETNNLVNVLKK
DKGPILIDSIGGFIMESIYKNDEEWENQIHLLLNLLKNRIKTTLIVGEQVGWSLVSEYEIGNKYIERLGDLQKRITRISE
ENWLTINGRAIKLDKISIEIPF
>Mature_182_residues
MENHGNNFAKVIFITGGTKSGKSEFAEYLGRKLPKITYIALSESRPDDLNWQKKILQHRKRRPKNWALIETNNLVNVLKK
DKGPILIDSIGGFIMESIYKNDEEWENQIHLLLNLLKNRIKTTLIVGEQVGWSLVSEYEIGNKYIERLGDLQKRITRISE
ENWLTINGRAIKLDKISIEIPF

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=24.3093922651934, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21119; Mature: 21119

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENHGNNFAKVIFITGGTKSGKSEFAEYLGRKLPKITYIALSESRPDDLNWQKKILQHRK
CCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHH
RRPKNWALIETNNLVNVLKKDKGPILIDSIGGFIMESIYKNDEEWENQIHLLLNLLKNRI
CCCCCEEEEECCHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KTTLIVGEQVGWSLVSEYEIGNKYIERLGDLQKRITRISEENWLTINGRAIKLDKISIEI
HHEEEECCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEEEEEE
PF
CC
>Mature Secondary Structure
MENHGNNFAKVIFITGGTKSGKSEFAEYLGRKLPKITYIALSESRPDDLNWQKKILQHRK
CCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHH
RRPKNWALIETNNLVNVLKKDKGPILIDSIGGFIMESIYKNDEEWENQIHLLLNLLKNRI
CCCCCEEEEECCHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KTTLIVGEQVGWSLVSEYEIGNKYIERLGDLQKRITRISEENWLTINGRAIKLDKISIEI
HHEEEECCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEEEEEE
PF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9601028; 10529169 [H]