Click here to switch to the map view.

The map label for this gene is tldD [C]

Identifier: 123966152

GI number: 123966152

Start: 821962

End: 823386

Strand: Reverse

Name: tldD [C]

Synonym: P9515_09191

Alternate gene names: 123966152

Gene position: 823386-821962 (Counterclockwise)

Preceding gene: 123966153

Following gene: 123966151

Centisome position: 48.32

GC content: 33.54

Gene sequence:

>1425_bases
ATGGTATCTTCGATTATTAACACTAGTGAAATTAAATTTGGAGAATGTAATAAAAAACTTCTAGAAGAAGTTATTTTCTA
TGGAATATCACTTGGTGCTGATTTTGTAGAATTGTTTATTGAAAATTCGGATAATTCAAGTGTTCTTGCAGAAGAAGATT
TTATTACAAGTGTTAGTCCATCATTTGGTAAAGGAGCAGGTATAAGAATATTTAAAGATAAAAGAGATGGTTTTGTTAGC
ACGAACGACTTATCAAAACATGGATTAATGAGATCAATTTCTCAAGCTATTGAAATGTTAGATATAACTGAAAAAACAAA
TAATTCTATATTCAATGGACTTAATAAACTAAAGGATTACAGTAAGTCAAAAATCAATTGGATTAATGAAGTACCTACAA
TATACGAAATAAGTGAAAAATTATTACTCAGCACAAAGTGTCTAAAAAAGGACAACAAAGTTGTTGTGAGGAAAGGGAGC
TACTCAAGAAATTGGCAAGAAGTAATAATAGCTTCAAGTGACGGAACTTACGCTACTGATATTAGATTACATCAAACAGT
AGGACTTAACTTAATTGCTAATGATGCTCAATATCGATCGAACGGCAGTAGAAGATTTGGATCACACGGAATTCCTAATG
AATTTAGATTATGGGACCATGAAAAAGCAGCAAATGAAGTATATGAGAGTTCATTGAATATGTTGTATGCAGACTATGTA
CAAGCTGGACAAATGCCAGTTGTTTTAGCTAATAAATTTGGTGGTGTAATATTTCATGAGGCCTGTGGTCATTTACTCGA
AACAACACAGATTGAACGCGGAACAACTCCATTTAGCGATAAGTTAAATAAAAAAATTGCTCATGAATCAGTTACGGCTA
TAGATGAAGGCCTCTCAGAAGGATCCTTTGGATCATTATCCATTGATGATGAAGGAATGGAACCTGAGAAATCAATTCTT
ATTAAGAATGGAATTTTAAAGAAATTTCTTTCTGATAGAGCAGGTGAACTAAGAACTGGTCACAAAAGAACTGGTAGTGG
TAGAAGGCAAAACTATTCATTTGCTGCTGCATCAAGAATGAGAAATACATATATAGCTAAAGGTGAATTCACAAAGGAAG
AATTAATAAATAGTATTGCTGATGGGCTTTACTGTAAATCTATGGGAGGTGGAAGTGTAGGGGCGACAGGTCAATTTAAT
TTTGCTGTTGAGGAAGGTTATTTAATAAAGAATGGAAAATTAACTAAACCTGTTAAAGGAGCCACATTGATAGGGGACGC
GAAAGAAGTCATGCCAAAAATATCTATGTGTGGAAATGATTTAGAGTTAGCACCAGGTTTTTGTGGCTCAGTAAGCGGAA
GCGTAAATGTAACAGTCGGTCAGCCACATATAAAAGTTGATTCAATAACTGTAGGAGGTAGATAA

Upstream 100 bases:

>100_bases
ACTGATAAGACTATACTTATTAAAACCTCTTGAAAGCAACGATTTTCAACCATCAATAAGATAATCCGACCTACTTAAGA
GAATAAGCTATAAGATTCAA

Downstream 100 bases:

>100_bases
AAATGAATGCAACAGAAATAACAAATCAAATAAAACACACAGCAAATATATTAAATATCGATAAATGGGATTACGGAGCT
AGTTTTTCTAATGATTATTC

Product: putative modulator of DNA gyrase; TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MVSSIINTSEIKFGECNKKLLEEVIFYGISLGADFVELFIENSDNSSVLAEEDFITSVSPSFGKGAGIRIFKDKRDGFVS
TNDLSKHGLMRSISQAIEMLDITEKTNNSIFNGLNKLKDYSKSKINWINEVPTIYEISEKLLLSTKCLKKDNKVVVRKGS
YSRNWQEVIIASSDGTYATDIRLHQTVGLNLIANDAQYRSNGSRRFGSHGIPNEFRLWDHEKAANEVYESSLNMLYADYV
QAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFSDKLNKKIAHESVTAIDEGLSEGSFGSLSIDDEGMEPEKSIL
IKNGILKKFLSDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEFTKEELINSIADGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTKPVKGATLIGDAKEVMPKISMCGNDLELAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR

Sequences:

>Translated_474_residues
MVSSIINTSEIKFGECNKKLLEEVIFYGISLGADFVELFIENSDNSSVLAEEDFITSVSPSFGKGAGIRIFKDKRDGFVS
TNDLSKHGLMRSISQAIEMLDITEKTNNSIFNGLNKLKDYSKSKINWINEVPTIYEISEKLLLSTKCLKKDNKVVVRKGS
YSRNWQEVIIASSDGTYATDIRLHQTVGLNLIANDAQYRSNGSRRFGSHGIPNEFRLWDHEKAANEVYESSLNMLYADYV
QAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFSDKLNKKIAHESVTAIDEGLSEGSFGSLSIDDEGMEPEKSIL
IKNGILKKFLSDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEFTKEELINSIADGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTKPVKGATLIGDAKEVMPKISMCGNDLELAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR
>Mature_474_residues
MVSSIINTSEIKFGECNKKLLEEVIFYGISLGADFVELFIENSDNSSVLAEEDFITSVSPSFGKGAGIRIFKDKRDGFVS
TNDLSKHGLMRSISQAIEMLDITEKTNNSIFNGLNKLKDYSKSKINWINEVPTIYEISEKLLLSTKCLKKDNKVVVRKGS
YSRNWQEVIIASSDGTYATDIRLHQTVGLNLIANDAQYRSNGSRRFGSHGIPNEFRLWDHEKAANEVYESSLNMLYADYV
QAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFSDKLNKKIAHESVTAIDEGLSEGSFGSLSIDDEGMEPEKSIL
IKNGILKKFLSDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEFTKEELINSIADGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTKPVKGATLIGDAKEVMPKISMCGNDLELAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=461, Percent_Identity=33.6225596529284, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI1790682, Length=454, Percent_Identity=23.1277533039648, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51902; Mature: 51902

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSIINTSEIKFGECNKKLLEEVIFYGISLGADFVELFIENSDNSSVLAEEDFITSVSP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHEEECCCCCCEEECCCHHCCCCC
SFGKGAGIRIFKDKRDGFVSTNDLSKHGLMRSISQAIEMLDITEKTNNSIFNGLNKLKDY
CCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
SKSKINWINEVPTIYEISEKLLLSTKCLKKDNKVVVRKGSYSRNWQEVIIASSDGTYATD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCEEEE
IRLHQTVGLNLIANDAQYRSNGSRRFGSHGIPNEFRLWDHEKAANEVYESSLNMLYADYV
EEEEEEECCEEEECCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFSDKLNKKIAHESVTAIDEGLSE
HCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GSFGSLSIDDEGMEPEKSILIKNGILKKFLSDRAGELRTGHKRTGSGRRQNYSFAAASRM
CCCCEEEECCCCCCCHHHEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RNTYIAKGEFTKEELINSIADGLYCKSMGGGSVGATGQFNFAVEEGYLIKNGKLTKPVKG
HHHEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCC
ATLIGDAKEVMPKISMCGNDLELAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR
CEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCC
>Mature Secondary Structure
MVSSIINTSEIKFGECNKKLLEEVIFYGISLGADFVELFIENSDNSSVLAEEDFITSVSP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHEEECCCCCCEEECCCHHCCCCC
SFGKGAGIRIFKDKRDGFVSTNDLSKHGLMRSISQAIEMLDITEKTNNSIFNGLNKLKDY
CCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
SKSKINWINEVPTIYEISEKLLLSTKCLKKDNKVVVRKGSYSRNWQEVIIASSDGTYATD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCEEEE
IRLHQTVGLNLIANDAQYRSNGSRRFGSHGIPNEFRLWDHEKAANEVYESSLNMLYADYV
EEEEEEECCEEEECCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFSDKLNKKIAHESVTAIDEGLSE
HCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GSFGSLSIDDEGMEPEKSILIKNGILKKFLSDRAGELRTGHKRTGSGRRQNYSFAAASRM
CCCCEEEECCCCCCCHHHEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RNTYIAKGEFTKEELINSIADGLYCKSMGGGSVGATGQFNFAVEEGYLIKNGKLTKPVKG
HHHEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCC
ATLIGDAKEVMPKISMCGNDLELAPGFCGSVSGSVNVTVGQPHIKVDSITVGGR
CEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]