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The map label for this gene is aroB

Identifier: 123965990

GI number: 123965990

Start: 684434

End: 685525

Strand: Reverse

Name: aroB

Synonym: P9515_07551

Alternate gene names: 123965990

Gene position: 685525-684434 (Counterclockwise)

Preceding gene: 123965992

Following gene: 123965988

Centisome position: 40.23

GC content: 30.59

Gene sequence:

>1092_bases
GTGAATAAGAACAAAATTATAGTTCCTTTAAGTAATAATTCATATGAAGTTACAATACGACAAGGAATCATAAACAGCAT
TGGGAAAGAGCTAACCCAAATTGGGATAAACAATAATAGAAAAATACTAATAGTTTCTAATAAAGAAATTTCAAACTTAT
TTGGGAGTAAACTTCTTAATGATTTAAAAAAATATAATTTTAGTGCTGAAATATTTAATATTAAAGCAGGAGAATCTTAT
AAGAATTTGGCAAGTTTAAGAGAGATATATGATGCTGCTTTTGAGTTTGGGTTAGACAGAAATGCCTTGCTGATTGCACT
AGGGGGAGGCATTGTAGGCGATGTAACTGGTTTTGCTGCAGCTACATGGTTAAGAGGTATTGATTATATTCAGATTCCGA
CAACACTATTATCTATGGTTGATTCATCGGTAGGCGGGAAAACAGCTGTTAATCATCCAAAAGGTAAAAATCTAATAGGA
GCTTTTTATCAACCCAAAGCAGTTTTTATTGATCCGGAAACTCTAAAAACTCTTCCTATAAGAGAATTTAAAGCAGGCAT
GGCAGAAGTTATCAAATATGGAGTGATAAAAGATAAAGAACTATTTGAATACTTAGAAATTGATAAAAATAGAGAAAAAA
TTCTCAATCTCGACAACGAATCATTAATAAAAATTATCAACAAGTCAATTAGAACAAAGTCATATATAGTCTCCAAAGAC
GAGAAAGAAAATGGAATTCGAGCAATATTAAATTATGGGCATTCATTTGGTCATGTAATAGAAAATTTATGTGGATATGG
AGAGTATCTACACGGCGAAGCAATATCAATTGGAATGAAAATTGCAGGAGATATTTCTACAGAAAAAAATTTATGGTTAA
AAGAGGATTCTTTAAGACAAGATAAACTCATTGAAAGTTATGGTCTACCAACACAAACTCCAAAAATCAAAAAGCATGAT
GTGATTACAATACTAATGGGTGATAAAAAGGTACGCGATGGAAAAATGAGGTTTATTCTACCTAAAGGGATTGGAGAAGT
TGATATTTTTAATGATATAAAAGAGTCACAATTCTTAAAATATTTCGATTAG

Upstream 100 bases:

>100_bases
TAACAACAGATTATTTTAATCTAATTTTTAAGTCACCATGAGGTTAGAATAAAAAAATAAAATTTTAATATTAATAAAAA
ACTCTTCCAGGATATGTATT

Downstream 100 bases:

>100_bases
CTAATACATCTTGATTTTATTTTTATTTTCTTGTTCTTAAATTTACTAAAAACAAACCATTTAAAATCTCCTAAACATAT
TGGGTCAACTAATCTCAATA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNKNKIIVPLSNNSYEVTIRQGIINSIGKELTQIGINNNRKILIVSNKEISNLFGSKLLNDLKKYNFSAEIFNIKAGESY
KNLASLREIYDAAFEFGLDRNALLIALGGGIVGDVTGFAAATWLRGIDYIQIPTTLLSMVDSSVGGKTAVNHPKGKNLIG
AFYQPKAVFIDPETLKTLPIREFKAGMAEVIKYGVIKDKELFEYLEIDKNREKILNLDNESLIKIINKSIRTKSYIVSKD
EKENGIRAILNYGHSFGHVIENLCGYGEYLHGEAISIGMKIAGDISTEKNLWLKEDSLRQDKLIESYGLPTQTPKIKKHD
VITILMGDKKVRDGKMRFILPKGIGEVDIFNDIKESQFLKYFD

Sequences:

>Translated_363_residues
MNKNKIIVPLSNNSYEVTIRQGIINSIGKELTQIGINNNRKILIVSNKEISNLFGSKLLNDLKKYNFSAEIFNIKAGESY
KNLASLREIYDAAFEFGLDRNALLIALGGGIVGDVTGFAAATWLRGIDYIQIPTTLLSMVDSSVGGKTAVNHPKGKNLIG
AFYQPKAVFIDPETLKTLPIREFKAGMAEVIKYGVIKDKELFEYLEIDKNREKILNLDNESLIKIINKSIRTKSYIVSKD
EKENGIRAILNYGHSFGHVIENLCGYGEYLHGEAISIGMKIAGDISTEKNLWLKEDSLRQDKLIESYGLPTQTPKIKKHD
VITILMGDKKVRDGKMRFILPKGIGEVDIFNDIKESQFLKYFD
>Mature_363_residues
MNKNKIIVPLSNNSYEVTIRQGIINSIGKELTQIGINNNRKILIVSNKEISNLFGSKLLNDLKKYNFSAEIFNIKAGESY
KNLASLREIYDAAFEFGLDRNALLIALGGGIVGDVTGFAAATWLRGIDYIQIPTTLLSMVDSSVGGKTAVNHPKGKNLIG
AFYQPKAVFIDPETLKTLPIREFKAGMAEVIKYGVIKDKELFEYLEIDKNREKILNLDNESLIKIINKSIRTKSYIVSKD
EKENGIRAILNYGHSFGHVIENLCGYGEYLHGEAISIGMKIAGDISTEKNLWLKEDSLRQDKLIESYGLPTQTPKIKKHD
VITILMGDKKVRDGKMRFILPKGIGEVDIFNDIKESQFLKYFD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=356, Percent_Identity=41.5730337078652, Blast_Score=280, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6320332, Length=264, Percent_Identity=38.2575757575758, Blast_Score=187, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_PROM5 (A2BW03)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001011071.1
- ProteinModelPortal:   A2BW03
- SMR:   A2BW03
- STRING:   A2BW03
- GeneID:   4719507
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_07551
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- BioCyc:   PMAR167542:P9515ORF_0792-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 40731; Mature: 40731

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNKIIVPLSNNSYEVTIRQGIINSIGKELTQIGINNNRKILIVSNKEISNLFGSKLLN
CCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
DLKKYNFSAEIFNIKAGESYKNLASLREIYDAAFEFGLDRNALLIALGGGIVGDVTGFAA
HHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHH
ATWLRGIDYIQIPTTLLSMVDSSVGGKTAVNHPKGKNLIGAFYQPKAVFIDPETLKTLPI
HHHHHCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEECHHHHHCCCH
REFKAGMAEVIKYGVIKDKELFEYLEIDKNREKILNLDNESLIKIINKSIRTKSYIVSKD
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHCCHHEEECCC
EKENGIRAILNYGHSFGHVIENLCGYGEYLHGEAISIGMKIAGDISTEKNLWLKEDSLRQ
CCCCHHHHHHHCCCHHHHHHHHHHCCCCHHCCCEEEEEEEEECCCCCCCCCEECCCCCHH
DKLIESYGLPTQTPKIKKHDVITILMGDKKVRDGKMRFILPKGIGEVDIFNDIKESQFLK
HHHHHHCCCCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHH
YFD
CCC
>Mature Secondary Structure
MNKNKIIVPLSNNSYEVTIRQGIINSIGKELTQIGINNNRKILIVSNKEISNLFGSKLLN
CCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
DLKKYNFSAEIFNIKAGESYKNLASLREIYDAAFEFGLDRNALLIALGGGIVGDVTGFAA
HHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHH
ATWLRGIDYIQIPTTLLSMVDSSVGGKTAVNHPKGKNLIGAFYQPKAVFIDPETLKTLPI
HHHHHCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEECHHHHHCCCH
REFKAGMAEVIKYGVIKDKELFEYLEIDKNREKILNLDNESLIKIINKSIRTKSYIVSKD
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHCCHHEEECCC
EKENGIRAILNYGHSFGHVIENLCGYGEYLHGEAISIGMKIAGDISTEKNLWLKEDSLRQ
CCCCHHHHHHHCCCHHHHHHHHHHCCCCHHCCCEEEEEEEEECCCCCCCCCEECCCCCHH
DKLIESYGLPTQTPKIKKHDVITILMGDKKVRDGKMRFILPKGIGEVDIFNDIKESQFLK
HHHHHHCCCCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHH
YFD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA