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The map label for this gene is mscS [C]

Identifier: 123965936

GI number: 123965936

Start: 635067

End: 636098

Strand: Reverse

Name: mscS [C]

Synonym: P9515_07011

Alternate gene names: 123965936

Gene position: 636098-635067 (Counterclockwise)

Preceding gene: 123965937

Following gene: 123965934

Centisome position: 37.33

GC content: 28.59

Gene sequence:

>1032_bases
ATGAAAGTATTTACAGAAAAATTGATTTTGGCAATTTCGATATTTCTTATTGGAATAATAATATCGATCATAATATCTAA
AATTTCCAAGGTTATTTTTAAAAGGATTTCTAAAAGAACAAAAACAAATTTCGATGATTTTATTTTTGATACAATTAATG
GAGTTTTAAAGCCAATAGGTTTTCTTCTATCAGGCTATTTCTCAATTGATTATTTTTTCACTGATGAAATAACTTTTATA
TCTGTAATCTTAAATATTCAAAAATTACTGATATTAATAATCATTATTAAAGCTCTTAATAAAGTACTAATTAAATCTTT
AACAGAATCCACTGCAAAAATTGATGATTCTTCAATCAGTTCGATGATCTCATCATTAACACCTTTAATTAAAGCATTTA
CATGGACTATAGGATCTATATTTTTCTTGCAAAATATAGGTGTGAAAATGACTGCGATTTGGGCATTGCTTAGTGCAGGC
GGTATCGGGGCAGGTTTAGCATTAAAAGATCCAGTTCAAGAATTTTTTGAATACATAACAATTTTGCTTGATAAACCTTT
TCAAAAAGGTGAATTTATAAAGTCCGATAGCGTATTAGGAATGGTAGAAAGGGTAGGAGTAAGATCCTCAAGAATAAGAA
GTATCAACGGAGAAGTAGTAGTAATGAGCAACAGTGCATTAACTAATGGGATAATTTCAAATTATGCTCAAATGAAGAAA
AGAAGACTTGTTCATAAATTGGGCGTAGTTTATGAAACCTCTCCATCTCTAATGAAAATGATTCCAAATATTATAAAAAA
AATTATTGAAGAAACTAAAGATGCCTCTTTTGATAGATGTCACTTTACAGATTTCGGAGACTTCAGTCTAAATTTCGAAT
TAGTTTATTTCATACCAACAAATAATTATTTAGCTGCTATGGAAGCTCAACAAAGTATTAACTTACGAATTATTGAAGAA
TTCTCCGCTAACAAAATAGAATTTGCATTCCCAACTCAAACATTAAATATTGAGAGATACGAACCCAAATGA

Upstream 100 bases:

>100_bases
AGAAATTAGCAATATAATTAAAAATCAAAGATAAATAAGACTGGTTTATTTTTAGAGATAATTTAAACTTTATATATTGT
TTTTAGAGAATTCATTAGAT

Downstream 100 bases:

>100_bases
TTGGCATAATTCTTCACTTAGATTCCAAAGTCTTAAAGCAAGATCACTTTTATTAGCTTCTTCACTAATCTCACTTTTGA
GTAATTTATGTTTTTTAAAA

Product: small mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKVFTEKLILAISIFLIGIIISIIISKISKVIFKRISKRTKTNFDDFIFDTINGVLKPIGFLLSGYFSIDYFFTDEITFI
SVILNIQKLLILIIIIKALNKVLIKSLTESTAKIDDSSISSMISSLTPLIKAFTWTIGSIFFLQNIGVKMTAIWALLSAG
GIGAGLALKDPVQEFFEYITILLDKPFQKGEFIKSDSVLGMVERVGVRSSRIRSINGEVVVMSNSALTNGIISNYAQMKK
RRLVHKLGVVYETSPSLMKMIPNIIKKIIEETKDASFDRCHFTDFGDFSLNFELVYFIPTNNYLAAMEAQQSINLRIIEE
FSANKIEFAFPTQTLNIERYEPK

Sequences:

>Translated_343_residues
MKVFTEKLILAISIFLIGIIISIIISKISKVIFKRISKRTKTNFDDFIFDTINGVLKPIGFLLSGYFSIDYFFTDEITFI
SVILNIQKLLILIIIIKALNKVLIKSLTESTAKIDDSSISSMISSLTPLIKAFTWTIGSIFFLQNIGVKMTAIWALLSAG
GIGAGLALKDPVQEFFEYITILLDKPFQKGEFIKSDSVLGMVERVGVRSSRIRSINGEVVVMSNSALTNGIISNYAQMKK
RRLVHKLGVVYETSPSLMKMIPNIIKKIIEETKDASFDRCHFTDFGDFSLNFELVYFIPTNNYLAAMEAQQSINLRIIEE
FSANKIEFAFPTQTLNIERYEPK
>Mature_343_residues
MKVFTEKLILAISIFLIGIIISIIISKISKVIFKRISKRTKTNFDDFIFDTINGVLKPIGFLLSGYFSIDYFFTDEITFI
SVILNIQKLLILIIIIKALNKVLIKSLTESTAKIDDSSISSMISSLTPLIKAFTWTIGSIFFLQNIGVKMTAIWALLSAG
GIGAGLALKDPVQEFFEYITILLDKPFQKGEFIKSDSVLGMVERVGVRSSRIRSINGEVVVMSNSALTNGIISNYAQMKK
RRLVHKLGVVYETSPSLMKMIPNIIKKIIEETKDASFDRCHFTDFGDFSLNFELVYFIPTNNYLAAMEAQQSINLRIIEE
FSANKIEFAFPTQTLNIERYEPK

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1787591, Length=211, Percent_Identity=26.5402843601896, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789291, Length=283, Percent_Identity=26.8551236749117, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 38698; Mature: 38698

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVFTEKLILAISIFLIGIIISIIISKISKVIFKRISKRTKTNFDDFIFDTINGVLKPIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLLSGYFSIDYFFTDEITFISVILNIQKLLILIIIIKALNKVLIKSLTESTAKIDDSSIS
HHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SMISSLTPLIKAFTWTIGSIFFLQNIGVKMTAIWALLSAGGIGAGLALKDPVQEFFEYIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ILLDKPFQKGEFIKSDSVLGMVERVGVRSSRIRSINGEVVVMSNSALTNGIISNYAQMKK
HHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHH
RRLVHKLGVVYETSPSLMKMIPNIIKKIIEETKDASFDRCHFTDFGDFSLNFELVYFIPT
HHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEEEEEEEEEC
NNYLAAMEAQQSINLRIIEEFSANKIEFAFPTQTLNIERYEPK
CCEEEEEHHHHCCCEEEEECCCCCEEEEECCCCEEECEECCCC
>Mature Secondary Structure
MKVFTEKLILAISIFLIGIIISIIISKISKVIFKRISKRTKTNFDDFIFDTINGVLKPIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLLSGYFSIDYFFTDEITFISVILNIQKLLILIIIIKALNKVLIKSLTESTAKIDDSSIS
HHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SMISSLTPLIKAFTWTIGSIFFLQNIGVKMTAIWALLSAGGIGAGLALKDPVQEFFEYIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ILLDKPFQKGEFIKSDSVLGMVERVGVRSSRIRSINGEVVVMSNSALTNGIISNYAQMKK
HHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHH
RRLVHKLGVVYETSPSLMKMIPNIIKKIIEETKDASFDRCHFTDFGDFSLNFELVYFIPT
HHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEEEEEEEEEC
NNYLAAMEAQQSINLRIIEEFSANKIEFAFPTQTLNIERYEPK
CCEEEEEHHHHCCCEEEEECCCCCEEEEECCCCEEECEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]