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The map label for this gene is folB [H]

Identifier: 123965891

GI number: 123965891

Start: 590604

End: 590966

Strand: Direct

Name: folB [H]

Synonym: P9515_06561

Alternate gene names: 123965891

Gene position: 590604-590966 (Clockwise)

Preceding gene: 123965890

Following gene: 123965892

Centisome position: 34.66

GC content: 26.45

Gene sequence:

>363_bases
ATGGGAACATATTTAAAAATTAAGAATATTAAACTTTGGTCAAGAGTTGGTGTCCTAGAAGAAGAAAGAGAATTAGGGCA
ACTTTTTAGTTTAGATGTACTTCTATGGGCTGATTTTGAAAAGTGTACTCAAAATGATGATATTAAAAGTACAGTTGATT
ATTCAAAATTAGTTGAAATAGTAAAATATCAATCCAAGAAAATATGTTGCTTTACTATTGAGAAATATTCAAATGAAATT
TTAAAAATTATTGATGAAGAGTTTGAACTTAGCCGAATTAAAATAATACTAACGAAATGTAAGCCTCCAATAATTGGTTT
TGATGGAGAGGTCTCAATTGTAAGAGTTTTAGAAAATAATTAA

Upstream 100 bases:

>100_bases
TAACGTATAAGTATTTTTTAAGAGGTGAAGGCCATAGTGTTGATGATTTTTCATCTGGAAAATCAATATATACCCATAAA
GATCTTTAAATATTATAAGA

Downstream 100 bases:

>100_bases
AAGTTTTGTCAAAAAGAGATCCCATAATATTAATTCATGGTCTTTGGAATACAGCAGATATCTTTTCTTCGATTACTTCG
AAACTTGATGAGATTGGAAT

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 120; Mature: 119

Protein sequence:

>120_residues
MGTYLKIKNIKLWSRVGVLEEERELGQLFSLDVLLWADFEKCTQNDDIKSTVDYSKLVEIVKYQSKKICCFTIEKYSNEI
LKIIDEEFELSRIKIILTKCKPPIIGFDGEVSIVRVLENN

Sequences:

>Translated_120_residues
MGTYLKIKNIKLWSRVGVLEEERELGQLFSLDVLLWADFEKCTQNDDIKSTVDYSKLVEIVKYQSKKICCFTIEKYSNEI
LKIIDEEFELSRIKIILTKCKPPIIGFDGEVSIVRVLENN
>Mature_119_residues
GTYLKIKNIKLWSRVGVLEEERELGQLFSLDVLLWADFEKCTQNDDIKSTVDYSKLVEIVKYQSKKICCFTIEKYSNEIL
KIIDEEFELSRIKIILTKCKPPIIGFDGEVSIVRVLENN

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13995; Mature: 13863

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTYLKIKNIKLWSRVGVLEEERELGQLFSLDVLLWADFEKCTQNDDIKSTVDYSKLVEI
CCCEEEEECEEEHHHCCCCHHHHHHHHHHHHHHEEEECHHHHCCCCCCCHHHCHHHHHHH
VKYQSKKICCFTIEKYSNEILKIIDEEFELSRIKIILTKCKPPIIGFDGEVSIVRVLENN
HHHCCCCEEEEEHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCEEECCCCEEEEEEEECC
>Mature Secondary Structure 
GTYLKIKNIKLWSRVGVLEEERELGQLFSLDVLLWADFEKCTQNDDIKSTVDYSKLVEI
CCEEEEECEEEHHHCCCCHHHHHHHHHHHHHHEEEECHHHHCCCCCCCHHHCHHHHHHH
VKYQSKKICCFTIEKYSNEILKIIDEEFELSRIKIILTKCKPPIIGFDGEVSIVRVLENN
HHHCCCCEEEEEHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCEEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]