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The map label for this gene is yggV [C]

Identifier: 123965847

GI number: 123965847

Start: 548312

End: 548896

Strand: Reverse

Name: yggV [C]

Synonym: P9515_06121

Alternate gene names: 123965847

Gene position: 548896-548312 (Counterclockwise)

Preceding gene: 123965856

Following gene: 123965845

Centisome position: 32.21

GC content: 34.36

Gene sequence:

>585_bases
TTGAACTTTCCTGCTCTTACAATTGCAAGCGGTAATCCAAAGAAGGTATCTGAAATATTTGAGATGTTAGACGTTTTATC
TTTAGAAGTAAAAAAGCAACCAGAATATCTAAACGTAGAGGAGACAGGTAAAACCTATTTTGAAAATGCTTTTTTAAAGG
CAAAAGCAGCTGCTTTAGAAACTAAGACTTGGGCATTAGCCGACGACTCAGGGCTTGAGGTTGATTATTTGGATGGACGA
CCTGGCATATATTCTGCAAGATATGCCAAAAGCAAAAATGAAAAGATTAGCAAGTTACTAAGAGAACTAAGCGATATCCC
TTACAGAAGCGCAAAATTTATTAGTTGTATGGTCTTATGTGATCCAAAGGGGAATTTAGTAAAAGATACAACTGGTATTT
GCTGGGGGGAAATCCTTAAAGAACCAAAATATCCTAACGGAGAATTTGAATCTATTTTCTGGATCAAGGAAGCTAATTGT
GTATACGGAGAATTAAGTCATTCTCAATTAATTAAACTTGGAAGTAGAGGCAAAGCAGCAAAAAATATATCTCCTTTTTT
GAAAAAAGAATTTGGAATTATTTAA

Upstream 100 bases:

>100_bases
GAGGCAGGCCCTGTCTACACAGGTGTGGAATGTTCAACCCTTCCTGTCTCTGTATCAAGTTTTAAAGTAAGATGATATTT
CAGATATTTATTATATTATT

Downstream 100 bases:

>100_bases
AAAACCTATTTAATTATTTGATATTTGCTCGATAGCTCTTATTGCAGCTGCTGCAGCCTCCTCGACATCTCCCTCTTTCC
CTGCAAGAGTTAACCTTCCA

Product: HAM1 family protein

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MNFPALTIASGNPKKVSEIFEMLDVLSLEVKKQPEYLNVEETGKTYFENAFLKAKAAALETKTWALADDSGLEVDYLDGR
PGIYSARYAKSKNEKISKLLRELSDIPYRSAKFISCMVLCDPKGNLVKDTTGICWGEILKEPKYPNGEFESIFWIKEANC
VYGELSHSQLIKLGSRGKAAKNISPFLKKEFGII

Sequences:

>Translated_194_residues
MNFPALTIASGNPKKVSEIFEMLDVLSLEVKKQPEYLNVEETGKTYFENAFLKAKAAALETKTWALADDSGLEVDYLDGR
PGIYSARYAKSKNEKISKLLRELSDIPYRSAKFISCMVLCDPKGNLVKDTTGICWGEILKEPKYPNGEFESIFWIKEANC
VYGELSHSQLIKLGSRGKAAKNISPFLKKEFGII
>Mature_194_residues
MNFPALTIASGNPKKVSEIFEMLDVLSLEVKKQPEYLNVEETGKTYFENAFLKAKAAALETKTWALADDSGLEVDYLDGR
PGIYSARYAKSKNEKISKLLRELSDIPYRSAKFISCMVLCDPKGNLVKDTTGICWGEILKEPKYPNGEFESIFWIKEANC
VYGELSHSQLIKLGSRGKAAKNISPFLKKEFGII

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=192, Percent_Identity=35.4166666666667, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21743; Mature: 21743

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPALTIASGNPKKVSEIFEMLDVLSLEVKKQPEYLNVEETGKTYFENAFLKAKAAALE
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEECHHHHCHHHHHHHHHHHHHHHHC
TKTWALADDSGLEVDYLDGRPGIYSARYAKSKNEKISKLLRELSDIPYRSAKFISCMVLC
CCEEEEECCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEE
DPKGNLVKDTTGICWGEILKEPKYPNGEFESIFWIKEANCVYGELSHSQLIKLGSRGKAA
CCCCCEECCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCEEEECCCHHHHHHHCCCCCCC
KNISPFLKKEFGII
CCCCHHHHHHCCCC
>Mature Secondary Structure
MNFPALTIASGNPKKVSEIFEMLDVLSLEVKKQPEYLNVEETGKTYFENAFLKAKAAALE
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEECHHHHCHHHHHHHHHHHHHHHHC
TKTWALADDSGLEVDYLDGRPGIYSARYAKSKNEKISKLLRELSDIPYRSAKFISCMVLC
CCEEEEECCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEE
DPKGNLVKDTTGICWGEILKEPKYPNGEFESIFWIKEANCVYGELSHSQLIKLGSRGKAA
CCCCCEECCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCEEEECCCHHHHHHHCCCCCCC
KNISPFLKKEFGII
CCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]