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The map label for this gene is cobO [H]

Identifier: 123965822

GI number: 123965822

Start: 524748

End: 525443

Strand: Reverse

Name: cobO [H]

Synonym: P9515_05871

Alternate gene names: 123965822

Gene position: 525443-524748 (Counterclockwise)

Preceding gene: 123965823

Following gene: 123965821

Centisome position: 30.83

GC content: 33.33

Gene sequence:

>696_bases
ATGCCAAGTGAAGAACAAACCTCTTCTAGGAAAACAACCAGTCTAGATCTTCAGGCTAAAAAACTTGGGATTGGAGGAAA
GTTATCTCCTGAAAACGATGAGAGCCTTTATAAAAAAAGAATGCAACAAAGAAAAGAGGTTCAATCAAAGAGATTAAAAG
AAAGGAAAACAAAAAAAGGATTATTAGTTGTTTTTACTGGTAATGGCAAAGGGAAAACAACTGCCTCCTTAGGTATGGCT
TTAAGAACTATTGGCCATGGTCATAAAGTAGCTATTATTCAATTTATTAAGGGTGGTTGGACTACTGGTGAAGAAAAAGC
ACTTAAAATGTTATCCCCAGATATTTCTTGGCATGCATTAGGAGAGGGATTCACATGGGAAACACAAGATAGAATAAGGG
ACGAAGAATTAGTTAAAGGAGCTTGGCAAGTTGCTAAAACATTCATCAAAGATGAATCTTATAAACTAATAATCCTTGAT
GAAATTAATATCGCAACAAAACTTGGGTATCTTTCTCCAAAAGAAATAATTACTTTCATACAAAGTGTAAATAAAAGAAA
AAATCATATTGTTTTAACTGGTAGAGGGGCTTCCGAATCAATAATTAATCAAGCAGATCTAGTAACAGAGATGAAATTAA
TTAAGCATCCCTTTAAAGAGCAAGGTATAAAAGCTCAGAAATGCATTGAGTTTTAG

Upstream 100 bases:

>100_bases
ATAACTAAACGTGATCAACAACAAGCAGTTAATAATGCTCTTTCAAAATATAAAAAACGTGAAATTTTCAAATCACTATA
ATGATAAATAAAGCACTTCT

Downstream 100 bases:

>100_bases
GGTTGATAAGCAGAATTTTATTTAAATTTCACATTATCCGACAAAGAAATGTTTAAAGACGCAAGCAATATCATATTAAA
AAAGGAATTCTTTATATTTA

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MPSEEQTSSRKTTSLDLQAKKLGIGGKLSPENDESLYKKRMQQRKEVQSKRLKERKTKKGLLVVFTGNGKGKTTASLGMA
LRTIGHGHKVAIIQFIKGGWTTGEEKALKMLSPDISWHALGEGFTWETQDRIRDEELVKGAWQVAKTFIKDESYKLIILD
EINIATKLGYLSPKEIITFIQSVNKRKNHIVLTGRGASESIINQADLVTEMKLIKHPFKEQGIKAQKCIEF

Sequences:

>Translated_231_residues
MPSEEQTSSRKTTSLDLQAKKLGIGGKLSPENDESLYKKRMQQRKEVQSKRLKERKTKKGLLVVFTGNGKGKTTASLGMA
LRTIGHGHKVAIIQFIKGGWTTGEEKALKMLSPDISWHALGEGFTWETQDRIRDEELVKGAWQVAKTFIKDESYKLIILD
EINIATKLGYLSPKEIITFIQSVNKRKNHIVLTGRGASESIINQADLVTEMKLIKHPFKEQGIKAQKCIEF
>Mature_230_residues
PSEEQTSSRKTTSLDLQAKKLGIGGKLSPENDESLYKKRMQQRKEVQSKRLKERKTKKGLLVVFTGNGKGKTTASLGMAL
RTIGHGHKVAIIQFIKGGWTTGEEKALKMLSPDISWHALGEGFTWETQDRIRDEELVKGAWQVAKTFIKDESYKLIILDE
INIATKLGYLSPKEIITFIQSVNKRKNHIVLTGRGASESIINQADLVTEMKLIKHPFKEQGIKAQKCIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=198, Percent_Identity=38.8888888888889, Blast_Score=157, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 26009; Mature: 25877

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSEEQTSSRKTTSLDLQAKKLGIGGKLSPENDESLYKKRMQQRKEVQSKRLKERKTKKG
CCCCHHHCCCCCEEECEEHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLVVFTGNGKGKTTASLGMALRTIGHGHKVAIIQFIKGGWTTGEEKALKMLSPDISWHAL
EEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHCCCCCEEEC
GEGFTWETQDRIRDEELVKGAWQVAKTFIKDESYKLIILDEINIATKLGYLSPKEIITFI
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHCCCCHHHHHHHH
QSVNKRKNHIVLTGRGASESIINQADLVTEMKLIKHPFKEQGIKAQKCIEF
HHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHCCC
>Mature Secondary Structure 
PSEEQTSSRKTTSLDLQAKKLGIGGKLSPENDESLYKKRMQQRKEVQSKRLKERKTKKG
CCCHHHCCCCCEEECEEHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLVVFTGNGKGKTTASLGMALRTIGHGHKVAIIQFIKGGWTTGEEKALKMLSPDISWHAL
EEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHCCCCCEEEC
GEGFTWETQDRIRDEELVKGAWQVAKTFIKDESYKLIILDEINIATKLGYLSPKEIITFI
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHCCCCHHHHHHHH
QSVNKRKNHIVLTGRGASESIINQADLVTEMKLIKHPFKEQGIKAQKCIEF
HHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]