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The map label for this gene is pyrH [H]

Identifier: 123965821

GI number: 123965821

Start: 523912

End: 524616

Strand: Reverse

Name: pyrH [H]

Synonym: P9515_05861

Alternate gene names: 123965821

Gene position: 524616-523912 (Counterclockwise)

Preceding gene: 123965822

Following gene: 123965820

Centisome position: 30.78

GC content: 37.73

Gene sequence:

>705_bases
ATGACTTACAAAAGAGTTCTTTTAAAACTTAGTGGCGAAGCACTAATGGGTGATAAACCGTATGGGATAGATCCTGCCAT
AGTCCAATCAATTGCTGAAGATGTAGAGAAGGTAATCGCAAATAATGTTCAACTTGCAATAGTTGTTGGTGGGGGCAATA
TATTTAGAGGACTAAAAGGTTCTGCTGATGGTATGGATAGAGCTACAGCAGATTATGTAGGAATGTTAGCAACAGTAATG
AATGCTATTTCCCTTCAAGATGGATTAGAGAGAGTTGGGGTAGAAACAAGAGTTCAAACAGCCATAGAGATGCAAGAAAT
TGCCGAGCCTTATATTAGAAGAAGAGCAATGAGGCATTTAGAGAAAGGCAGAGTTGTAGTTTTTGGAGGTGGTTGTGGAA
ACCCATTTTTTACTACTGATACGACTGCTGCATTGAGGGCTGCCGAGATAAATGCTGAAGTTGTTATGAAAGCTACAAAA
GTTGATGGGGTTTATGATCGTGATCCAAATAAATTTAATGAAGCAAAAAAGTACTCTTCTCTGAGTTATCAACAAGTTCT
TAGTGATGAAATTGCTGTAATGGATAGTACCGCTATCGCTCTATGCAAAGATAATAATATTCCCATAATGGTTTTTGATA
TCTTCAAAAAAGGGAACATCTCGAGAGCTGTTGCTGGAGAGTCCATAGGATCTTTAATAAGTTAA

Upstream 100 bases:

>100_bases
CATTATCCGACAAAGAAATGTTTAAAGACGCAAGCAATATCATATTAAAAAAGGAATTCTTTATATTTACTTGCTAAAGT
CTTAAAAGATTGATTAGTGA

Downstream 100 bases:

>100_bases
AACTTATTTTAATTACTTTTTTAATTATGAAAGAACAAGAAATTCAATCAAGTATGAATAAAAGTGTTGAGGCCACTCAA
AGAAACTTTAATACAATAAG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTYKRVLLKLSGEALMGDKPYGIDPAIVQSIAEDVEKVIANNVQLAIVVGGGNIFRGLKGSADGMDRATADYVGMLATVM
NAISLQDGLERVGVETRVQTAIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATK
VDGVYDRDPNKFNEAKKYSSLSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISRAVAGESIGSLIS

Sequences:

>Translated_234_residues
MTYKRVLLKLSGEALMGDKPYGIDPAIVQSIAEDVEKVIANNVQLAIVVGGGNIFRGLKGSADGMDRATADYVGMLATVM
NAISLQDGLERVGVETRVQTAIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATK
VDGVYDRDPNKFNEAKKYSSLSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISRAVAGESIGSLIS
>Mature_233_residues
TYKRVLLKLSGEALMGDKPYGIDPAIVQSIAEDVEKVIANNVQLAIVVGGGNIFRGLKGSADGMDRATADYVGMLATVMN
AISLQDGLERVGVETRVQTAIEMQEIAEPYIRRRAMRHLEKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATKV
DGVYDRDPNKFNEAKKYSSLSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISRAVAGESIGSLIS

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=232, Percent_Identity=45.6896551724138, Blast_Score=220, Evalue=7e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25286; Mature: 25155

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYKRVLLKLSGEALMGDKPYGIDPAIVQSIAEDVEKVIANNVQLAIVVGGGNIFRGLKG
CCHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCC
SADGMDRATADYVGMLATVMNAISLQDGLERVGVETRVQTAIEMQEIAEPYIRRRAMRHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATKVDGVYDRDPNKFNEAKKYSS
HCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHEEEEHHCCCCCCCCCCHHHHHHHHHH
LSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISRAVAGESIGSLIS
HHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TYKRVLLKLSGEALMGDKPYGIDPAIVQSIAEDVEKVIANNVQLAIVVGGGNIFRGLKG
CHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCC
SADGMDRATADYVGMLATVMNAISLQDGLERVGVETRVQTAIEMQEIAEPYIRRRAMRHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKGRVVVFGGGCGNPFFTTDTTAALRAAEINAEVVMKATKVDGVYDRDPNKFNEAKKYSS
HCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHEEEEHHCCCCCCCCCCHHHHHHHHHH
LSYQQVLSDEIAVMDSTAIALCKDNNIPIMVFDIFKKGNISRAVAGESIGSLIS
HHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA