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The map label for this gene is qri7

Identifier: 123965769

GI number: 123965769

Start: 476414

End: 477484

Strand: Direct

Name: qri7

Synonym: P9515_05341

Alternate gene names: 123965769

Gene position: 476414-477484 (Clockwise)

Preceding gene: 123965766

Following gene: 123965770

Centisome position: 27.96

GC content: 36.6

Gene sequence:

>1071_bases
ATGCTCAAAGTTCTGGCTATTGAAACAAGTTGTGATGAGACGTCAGTCTCCGTTGTCTCTAATAGTAATGATATTTATAA
AATACATTCAAATATTGTTGCATCACAAATTGAAGATCATTCTAAGTGGGGAGGAGTGGTACCAGAACTCGCAGCAAGAA
AACATTTAGAGTTAATTCCTTTTGTCCTTGAAGAGGCTCTAGAGGAATCAAAAATAAGTATTGAAGAGATTGATGCTATA
GCCTCGACCGTAACTCCAGGATTAGTAGGCTGCTTAAGAGTTGGTTCCATAACTGCCAGATCACTATGTACTTTATACTC
AAAACCGTTTTTGGGGATACATCACTTAGAAGGACATCTATCTTCAATATTATTTTCAAAGAATTATCCCAAGCCTCCTT
TTTTAACCTTACTTGTTAGTGGGGGACATACCGAATTAATTAAAATTGGTGAGAGAAGAATAATGCAAAGACTTGGCAGA
AGTTATGATGATGCGGCTGGGGAAGCCTTCGATAAAGTTGGAAGATTATTAGGACTTAGTTACCCTGGGGGGCCTGCAAT
TGCGGAAATTGCCAAAAAAGGCAATTCCTTAAAATTTAACTTACCTAAGTGTAAAATCTCTGACAAGAAAGGGGGTTTTT
TGAAATATGATTTCTCTTTTAGTGGTTTAAAAACGGCTGTATTGAGGTTAGTTGAAAAAATAAGGTTAAATGGAGATGAA
ATACCAATTCCAGATATCGCTGCTAGTTTTGAGAGGGTTGTGTCAGAAGTATTGGTAGAGAGGACAATAAAATGCGCAGT
TGATTATGATTTAGATAACGTTGTTGTTGTAGGTGGAGTTGCGGCAAACGATACGTTAAGAAAAATGATGATTAGTGAAG
CAGGTAAAAAATCTATTAAAGTTCATTTAGCTCCATTAAATCTTTGCACCGATAATGCTGCGATGATTGGAGCCGCTGCC
TTATTTAGACTTAAATTTAAGGCACATGAAAGTTCTCTTGAATTGGGTATTTCAGGAAGACTTCCTATTGACCAAGCAAA
TACTCTTTATGCAAACAAACCTCCTTTCTAA

Upstream 100 bases:

>100_bases
GTATGATTGAAAAAAAGAATTTCATAAGTTGCAATCTTTAATTCCTTTTGATGTTTTAATTAAGAAATTATTATTAAAAT
AGAACAGTATCGAATCAAAT

Downstream 100 bases:

>100_bases
TAACTAATGAAAAAACAAACCAAAATAGAGCTTAAAGAAACAAAAAAGTTTGTTGATAAACAAGAGCTTAATTTATGGAA
AAGAGGTTTTACTCCTCAAG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MLKVLAIETSCDETSVSVVSNSNDIYKIHSNIVASQIEDHSKWGGVVPELAARKHLELIPFVLEEALEESKISIEEIDAI
ASTVTPGLVGCLRVGSITARSLCTLYSKPFLGIHHLEGHLSSILFSKNYPKPPFLTLLVSGGHTELIKIGERRIMQRLGR
SYDDAAGEAFDKVGRLLGLSYPGGPAIAEIAKKGNSLKFNLPKCKISDKKGGFLKYDFSFSGLKTAVLRLVEKIRLNGDE
IPIPDIAASFERVVSEVLVERTIKCAVDYDLDNVVVVGGVAANDTLRKMMISEAGKKSIKVHLAPLNLCTDNAAMIGAAA
LFRLKFKAHESSLELGISGRLPIDQANTLYANKPPF

Sequences:

>Translated_356_residues
MLKVLAIETSCDETSVSVVSNSNDIYKIHSNIVASQIEDHSKWGGVVPELAARKHLELIPFVLEEALEESKISIEEIDAI
ASTVTPGLVGCLRVGSITARSLCTLYSKPFLGIHHLEGHLSSILFSKNYPKPPFLTLLVSGGHTELIKIGERRIMQRLGR
SYDDAAGEAFDKVGRLLGLSYPGGPAIAEIAKKGNSLKFNLPKCKISDKKGGFLKYDFSFSGLKTAVLRLVEKIRLNGDE
IPIPDIAASFERVVSEVLVERTIKCAVDYDLDNVVVVGGVAANDTLRKMMISEAGKKSIKVHLAPLNLCTDNAAMIGAAA
LFRLKFKAHESSLELGISGRLPIDQANTLYANKPPF
>Mature_356_residues
MLKVLAIETSCDETSVSVVSNSNDIYKIHSNIVASQIEDHSKWGGVVPELAARKHLELIPFVLEEALEESKISIEEIDAI
ASTVTPGLVGCLRVGSITARSLCTLYSKPFLGIHHLEGHLSSILFSKNYPKPPFLTLLVSGGHTELIKIGERRIMQRLGR
SYDDAAGEAFDKVGRLLGLSYPGGPAIAEIAKKGNSLKFNLPKCKISDKKGGFLKYDFSFSGLKTAVLRLVEKIRLNGDE
IPIPDIAASFERVVSEVLVERTIKCAVDYDLDNVVVVGGVAANDTLRKMMISEAGKKSIKVHLAPLNLCTDNAAMIGAAA
LFRLKFKAHESSLELGISGRLPIDQANTLYANKPPF

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=343, Percent_Identity=34.6938775510204, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI8923380, Length=355, Percent_Identity=28.7323943661972, Blast_Score=122, Evalue=5e-28,
Organism=Escherichia coli, GI1789445, Length=343, Percent_Identity=42.2740524781341, Blast_Score=247, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI17557464, Length=375, Percent_Identity=30.4, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71995670, Length=328, Percent_Identity=28.0487804878049, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320099, Length=344, Percent_Identity=31.9767441860465, Blast_Score=122, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6322891, Length=300, Percent_Identity=27, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20129063, Length=344, Percent_Identity=31.6860465116279, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21357207, Length=337, Percent_Identity=28.486646884273, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_PROM5 (A2BVD2)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001010850.1
- ProteinModelPortal:   A2BVD2
- SMR:   A2BVD2
- STRING:   A2BVD2
- MEROPS:   M22.001
- GeneID:   4719749
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_05341
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PLYGVNH
- ProtClustDB:   PRK09604
- BioCyc:   PMAR167542:P9515ORF_0568-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 38639; Mature: 38639

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVLAIETSCDETSVSVVSNSNDIYKIHSNIVASQIEDHSKWGGVVPELAARKHLELIP
CEEEEEEECCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FVLEEALEESKISIEEIDAIASTVTPGLVGCLRVGSITARSLCTLYSKPFLGIHHLEGHL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHH
SSILFSKNYPKPPFLTLLVSGGHTELIKIGERRIMQRLGRSYDDAAGEAFDKVGRLLGLS
HHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
YPGGPAIAEIAKKGNSLKFNLPKCKISDKKGGFLKYDFSFSGLKTAVLRLVEKIRLNGDE
CCCCHHHHHHHHCCCCEEEECCCEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCC
IPIPDIAASFERVVSEVLVERTIKCAVDYDLDNVVVVGGVAANDTLRKMMISEAGKKSIK
CCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCCEEE
VHLAPLNLCTDNAAMIGAAALFRLKFKAHESSLELGISGRLPIDQANTLYANKPPF
EEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLKVLAIETSCDETSVSVVSNSNDIYKIHSNIVASQIEDHSKWGGVVPELAARKHLELIP
CEEEEEEECCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FVLEEALEESKISIEEIDAIASTVTPGLVGCLRVGSITARSLCTLYSKPFLGIHHLEGHL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHH
SSILFSKNYPKPPFLTLLVSGGHTELIKIGERRIMQRLGRSYDDAAGEAFDKVGRLLGLS
HHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
YPGGPAIAEIAKKGNSLKFNLPKCKISDKKGGFLKYDFSFSGLKTAVLRLVEKIRLNGDE
CCCCHHHHHHHHCCCCEEEECCCEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCC
IPIPDIAASFERVVSEVLVERTIKCAVDYDLDNVVVVGGVAANDTLRKMMISEAGKKSIK
CCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCCEEE
VHLAPLNLCTDNAAMIGAAALFRLKFKAHESSLELGISGRLPIDQANTLYANKPPF
EEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA