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The map label for this gene is ubiA [H]

Identifier: 123965754

GI number: 123965754

Start: 465446

End: 466333

Strand: Reverse

Name: ubiA [H]

Synonym: P9515_05191

Alternate gene names: 123965754

Gene position: 466333-465446 (Counterclockwise)

Preceding gene: 123965756

Following gene: 123965753

Centisome position: 27.36

GC content: 31.19

Gene sequence:

>888_bases
GTGATAAATACAGACTTCAGATATAAATTAAATATCCTTTTTGAACTTCTAAGGTGGAATAAACCAACTGGTCGACTTAT
TCTACTTATCCCTGCTGGGTGGAGTTTGTATCTTACTCCAGAATCAAATCCAAGCTTTCATATGTTATTGAAAATAATAA
TGGGGGGATTATTAGTTAGTGGTTTAGGTTGTATTGCTAATGATATTTGGGATAAAAAAATAGATCAAAAAGTCTTAAGA
ACCCAAAACAGACCTCTTGCTGCAAATAAGATTGGTAATAAAACAGCTTATTTAATTCTTATATTTTTAATAATATGCAG
TTTCTTTTTAACTTTGTCACTTCCAGAGAATGGAAGACTACTTTCTATTTCACTTGCTTTTTTTGCCCTGCCGTTAATCC
TAATTTACCCTTCTGCAAAAAGATGGTTTAAATATCCCCAACTTATCTTGTCATTATGCTGGGGATTCGCAGTTTTGATA
CCTTGGGCTGCTAACGAAGGGGATATTAAAAGTATTGTTTTACTTTTTTGCTGGCTCGCTACAATTTTTTGGACATTTGG
TTTTGATACTGTATATGCTTTGGCTGATATGAAATATGACCTTAAAATTGGGGTGAATAGTTCTGCGGTTAACCTTGCAT
CTAATACAAAAATCACCATACAAATTTGTTATTTTCTGACTTCCAGTTTTCTTGCAATTTGTGCTTTAATCAATCAATTA
AATTTAATTTTTTGGCCCATTTGGTTAATAACAGCTTTTTTAATGCAAAAAGATATCTTAAAAATCTTCCCTGAAAGTAA
TCATTCCATTAAAAAAATTGGTAATCATTTCAAAAACCAAACAATATATGGTGGATTAATTTTGTTGGGAATCATAATCT
CCTCATAA

Upstream 100 bases:

>100_bases
ATCCTAAATACCGTAATTAATATACTTAAAATTGATTATTAAATTATAGAATTAATTAAATACTAGTTAGATTATTTAAA
GTTATGAAATATAAGAACTC

Downstream 100 bases:

>100_bases
ATTATTAAACTAATGTTAACTAAATTAAAAAAAGGCGATGAAATCAACATTTTAGCGCCTGCTTCTTTTATCGATAAAGA
AGAAAATTTTACAAAAGGCA

Product: prenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MINTDFRYKLNILFELLRWNKPTGRLILLIPAGWSLYLTPESNPSFHMLLKIIMGGLLVSGLGCIANDIWDKKIDQKVLR
TQNRPLAANKIGNKTAYLILIFLIICSFFLTLSLPENGRLLSISLAFFALPLILIYPSAKRWFKYPQLILSLCWGFAVLI
PWAANEGDIKSIVLLFCWLATIFWTFGFDTVYALADMKYDLKIGVNSSAVNLASNTKITIQICYFLTSSFLAICALINQL
NLIFWPIWLITAFLMQKDILKIFPESNHSIKKIGNHFKNQTIYGGLILLGIIISS

Sequences:

>Translated_295_residues
MINTDFRYKLNILFELLRWNKPTGRLILLIPAGWSLYLTPESNPSFHMLLKIIMGGLLVSGLGCIANDIWDKKIDQKVLR
TQNRPLAANKIGNKTAYLILIFLIICSFFLTLSLPENGRLLSISLAFFALPLILIYPSAKRWFKYPQLILSLCWGFAVLI
PWAANEGDIKSIVLLFCWLATIFWTFGFDTVYALADMKYDLKIGVNSSAVNLASNTKITIQICYFLTSSFLAICALINQL
NLIFWPIWLITAFLMQKDILKIFPESNHSIKKIGNHFKNQTIYGGLILLGIIISS
>Mature_295_residues
MINTDFRYKLNILFELLRWNKPTGRLILLIPAGWSLYLTPESNPSFHMLLKIIMGGLLVSGLGCIANDIWDKKIDQKVLR
TQNRPLAANKIGNKTAYLILIFLIICSFFLTLSLPENGRLLSISLAFFALPLILIYPSAKRWFKYPQLILSLCWGFAVLI
PWAANEGDIKSIVLLFCWLATIFWTFGFDTVYALADMKYDLKIGVNSSAVNLASNTKITIQICYFLTSSFLAICALINQL
NLIFWPIWLITAFLMQKDILKIFPESNHSIKKIGNHFKNQTIYGGLILLGIIISS

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=288, Percent_Identity=29.1666666666667, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1790473, Length=294, Percent_Identity=32.312925170068, Blast_Score=127, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17553718, Length=288, Percent_Identity=29.5138888888889, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32565247, Length=288, Percent_Identity=29.1666666666667, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17553720, Length=345, Percent_Identity=25.5072463768116, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32565245, Length=143, Percent_Identity=34.2657342657343, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI32565243, Length=143, Percent_Identity=34.2657342657343, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324370, Length=231, Percent_Identity=29.004329004329, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21355567, Length=285, Percent_Identity=31.2280701754386, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33491; Mature: 33491

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINTDFRYKLNILFELLRWNKPTGRLILLIPAGWSLYLTPESNPSFHMLLKIIMGGLLVS
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHH
GLGCIANDIWDKKIDQKVLRTQNRPLAANKIGNKTAYLILIFLIICSFFLTLSLPENGRL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHEECCCCCCCE
LSISLAFFALPLILIYPSAKRWFKYPQLILSLCWGFAVLIPWAANEGDIKSIVLLFCWLA
EEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
TIFWTFGFDTVYALADMKYDLKIGVNSSAVNLASNTKITIQICYFLTSSFLAICALINQL
HHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHH
NLIFWPIWLITAFLMQKDILKIFPESNHSIKKIGNHFKNQTIYGGLILLGIIISS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MINTDFRYKLNILFELLRWNKPTGRLILLIPAGWSLYLTPESNPSFHMLLKIIMGGLLVS
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHH
GLGCIANDIWDKKIDQKVLRTQNRPLAANKIGNKTAYLILIFLIICSFFLTLSLPENGRL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHEECCCCCCCE
LSISLAFFALPLILIYPSAKRWFKYPQLILSLCWGFAVLIPWAANEGDIKSIVLLFCWLA
EEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
TIFWTFGFDTVYALADMKYDLKIGVNSSAVNLASNTKITIQICYFLTSSFLAICALINQL
HHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHH
NLIFWPIWLITAFLMQKDILKIFPESNHSIKKIGNHFKNQTIYGGLILLGIIISS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA