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The map label for this gene is ubiE [C]

Identifier: 123965712

GI number: 123965712

Start: 425478

End: 426272

Strand: Reverse

Name: ubiE [C]

Synonym: P9515_04771

Alternate gene names: 123965712

Gene position: 426272-425478 (Counterclockwise)

Preceding gene: 123965714

Following gene: 123965711

Centisome position: 25.01

GC content: 31.32

Gene sequence:

>795_bases
ATGTCTAGCGATTGCTGCAATACTGATGAGTCAAATAAAAATTTGAAAGGTCTTGATCATAAAGATGCTATCCAAGAAAG
GTATGGTTCTGCTGCATTAGAAAAAGAGAGTTGTCTTTGTACTCCTGTTGGTTTTAATCCTGTTTTACTTGAAGCAATTC
CTGAAGAAGTTATTGAAAGAGATTATGGATGTGGTGATCCAACAAAATATGTACAGAAGAATGATATTGTTTTAGATCTT
GGTAGTGGGAGTGGCAAAAATGCCTTTATTTGTTCTCAAATTGTTGGGGAAGAGGGGAAAGTAATTGGGGTTGATCAAAA
TCCTGATATGCTTACATTATCAAGATCTGCCTCCAAAAAATTTTCAGAAAAGATCGGTTTCAACAATACAGAATTTCTTA
AAGGGTCAATTGAAAATCTCGATGAATTAAATAAAGATTTAAATCCATTAATAGCAGACAAGTCAATTGATATTATTTTA
AGTAATTGTGTTTTAAATTTAGTAAATCCTGAATCTAGAAATAATCTTTTAAGAAATATAAAAAGAGTTCTTAAAGGTAA
CGGCAGAATAGCTATTAGCGATATTGTCTCAAGTAAAAAAGTTCCTTTAAGATTGCAAAATGATCATGATCTATGGACAG
GATGTATAAGTGGAGCATGGTATGAGCCGGAATTCCTTAATGATTTTAAAGATCTAGGTTTTAAAAACTTAGAATTCGCT
GAAAGAAGTAATGAACCTTGGAAAGTTATTGAAGATATTGAATTTAGAACAGTTACTTTAGTAGGGAATATTTAG

Upstream 100 bases:

>100_bases
ACCGAGGTGTAAGCTACACTAAATAATTTAATTCCAAAAAAAAACCTCTTCTTAGGGGTTTTTTTTTGGCTATATTTATT
TAAGTATTAAGATTACTTTT

Downstream 100 bases:

>100_bases
TCCTTCTCAAGAAATTTAATTTAAAAATTTTAATGACAATTAATTTAAGAGAACAAATACCCGCATTAAAAAACAAATAT
TACTTCAATTATGGAGGTCA

Product: putative methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Arsenite S-Adenosylmethyltransferase; Methyltransferase; Arsenite Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase Domain Family; UbiE/COQ5 Methyltransferase; Methyltransferase-Like; UbiE/COQ5 Family Methlytransferase; Arsenic Methyltransferase; 2-Heptaprenyl-1 4-Naphthoquinone Methyltransferase; Protein Containing Methyltransferase Domain; ArsR Family Transcriptional Regulator; SAM-Dependent Methyltransferases; Cyclopropane-Fatty-Acyl-Phospholipid Synthase; Methyltransferase UbiE-Family; Radical SAM Domain-Containing Protein; Transcriptional Regulator ArsR Family; Methyltransferase Domain Family Protein

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSSDCCNTDESNKNLKGLDHKDAIQERYGSAALEKESCLCTPVGFNPVLLEAIPEEVIERDYGCGDPTKYVQKNDIVLDL
GSGSGKNAFICSQIVGEEGKVIGVDQNPDMLTLSRSASKKFSEKIGFNNTEFLKGSIENLDELNKDLNPLIADKSIDIIL
SNCVLNLVNPESRNNLLRNIKRVLKGNGRIAISDIVSSKKVPLRLQNDHDLWTGCISGAWYEPEFLNDFKDLGFKNLEFA
ERSNEPWKVIEDIEFRTVTLVGNI

Sequences:

>Translated_264_residues
MSSDCCNTDESNKNLKGLDHKDAIQERYGSAALEKESCLCTPVGFNPVLLEAIPEEVIERDYGCGDPTKYVQKNDIVLDL
GSGSGKNAFICSQIVGEEGKVIGVDQNPDMLTLSRSASKKFSEKIGFNNTEFLKGSIENLDELNKDLNPLIADKSIDIIL
SNCVLNLVNPESRNNLLRNIKRVLKGNGRIAISDIVSSKKVPLRLQNDHDLWTGCISGAWYEPEFLNDFKDLGFKNLEFA
ERSNEPWKVIEDIEFRTVTLVGNI
>Mature_263_residues
SSDCCNTDESNKNLKGLDHKDAIQERYGSAALEKESCLCTPVGFNPVLLEAIPEEVIERDYGCGDPTKYVQKNDIVLDLG
SGSGKNAFICSQIVGEEGKVIGVDQNPDMLTLSRSASKKFSEKIGFNNTEFLKGSIENLDELNKDLNPLIADKSIDIILS
NCVLNLVNPESRNNLLRNIKRVLKGNGRIAISDIVSSKKVPLRLQNDHDLWTGCISGAWYEPEFLNDFKDLGFKNLEFAE
RSNEPWKVIEDIEFRTVTLVGNI

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI109389364, Length=254, Percent_Identity=33.8582677165354, Blast_Score=118, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29373; Mature: 29241

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDCCNTDESNKNLKGLDHKDAIQERYGSAALEKESCLCTPVGFNPVLLEAIPEEVIER
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCCCEEECCCCCHHHHHHHHHHHHHH
DYGCGDPTKYVQKNDIVLDLGSGSGKNAFICSQIVGEEGKVIGVDQNPDMLTLSRSASKK
CCCCCCCHHHHCCCCEEEECCCCCCCCEEEEHHHHCCCCCEEEECCCCCEEEEECHHHHH
FSEKIGFNNTEFLKGSIENLDELNKDLNPLIADKSIDIILSNCVLNLVNPESRNNLLRNI
HHHHHCCCCHHHHHCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
KRVLKGNGRIAISDIVSSKKVPLRLQNDHDLWTGCISGAWYEPEFLNDFKDLGFKNLEFA
HHHHCCCCCEEEEEHHCCCCCCEEECCCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCHHH
ERSNEPWKVIEDIEFRTVTLVGNI
HCCCCCCCHHCCCCEEEEEEEECC
>Mature Secondary Structure 
SSDCCNTDESNKNLKGLDHKDAIQERYGSAALEKESCLCTPVGFNPVLLEAIPEEVIER
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCCCEEECCCCCHHHHHHHHHHHHHH
DYGCGDPTKYVQKNDIVLDLGSGSGKNAFICSQIVGEEGKVIGVDQNPDMLTLSRSASKK
CCCCCCCHHHHCCCCEEEECCCCCCCCEEEEHHHHCCCCCEEEECCCCCEEEEECHHHHH
FSEKIGFNNTEFLKGSIENLDELNKDLNPLIADKSIDIILSNCVLNLVNPESRNNLLRNI
HHHHHCCCCHHHHHCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
KRVLKGNGRIAISDIVSSKKVPLRLQNDHDLWTGCISGAWYEPEFLNDFKDLGFKNLEFA
HHHHCCCCCEEEEEHHCCCCCCEEECCCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCHHH
ERSNEPWKVIEDIEFRTVTLVGNI
HCCCCCCCHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA