Click here to switch to the map view.

The map label for this gene is menA [H]

Identifier: 123965440

GI number: 123965440

Start: 187149

End: 188066

Strand: Reverse

Name: menA [H]

Synonym: P9515_02051

Alternate gene names: 123965440

Gene position: 188066-187149 (Counterclockwise)

Preceding gene: 123965442

Following gene: 123965439

Centisome position: 11.04

GC content: 29.63

Gene sequence:

>918_bases
ATGAATGAAAGAAATAAAAGTTTATGGAAACAAGCAATAAAATGGCCACTTTATTCCGTTGCAATTTTACCAGTTTTTAT
TTCAGGAGCTTATACCCTCAACTCTTTTAAAAATATCAAAATATCTAACTTAATAGCATTCACAATAGCTGCAATATTAA
TACTCATTTGGGAAAATCTAACTAATGATTTATTTGATTCAGAAACAGGAATTGATGAATTTAAATTCCATTCCATAGTC
AACCTTGTTCGAAGTAAAAAAATAATTTCAACTATCGCATATACATCTCTATTGATTGGGTTATTGGTAATTGCCATAAT
TTCAATATCGACAAGCATAAATGTCATGATATTGGTAGTCTCATGCTGCTTCTTAGGATATTTATATCAAGGACCACCTT
TTCGTTTGGGATACCAAGGTTTGGGAGAGCCATTATGCTGGTTAGCTTTTGGGCCCTTAACTTACTCCGCTGCTTTAATT
GCACTCAACCCATCAGATATATATACGATTACTATCCCTTGGAAAGATTCATTTTTACTTGGTTCAGGATCTTCATTAGC
AACAACTCTAATACTATTTTGCTCTCATTTTCATCAAATCGAAGAAGATAAAAAACATGGTAAAAATTCACCTTTAGTAC
GTTTAGGCCCAAAAAAAGGAGCCAAACTAATACCATGGATAGTTTTTATAGTTTATTTTTTCCAACTTTTTATAATTATT
AATGGATTTATTCCCATACTTTGTATTCTTTTTCTTATTAGTTTGCCACAATCAATAAAGCTTATAACTTTATTGAAATC
TTCATATAACAAACCTGAAGTAATAAAAAATTGTAAATTTATTGCGGTCAAATTTCAAACTCTAAATGGAATTGGATTAA
TAGCAGGATTAATTATTGATTACTTGATTAATAAATGA

Upstream 100 bases:

>100_bases
ACTTATTGAAAATAACTAAAAAACATGTATTAAAGTAAAAAATGTAACTCAATTTATAAACTATATTTAATAATTATAGT
TTTTATTAACTCCATTAAAA

Downstream 100 bases:

>100_bases
ACTTAACTTTTAAAAAAAAATCTTTTTTATTTAAATTATCTTCTAAGGTAGAAAATTCAAAGACAACATTTAAAAATAAA
TCTGGGTGGATAATTAAATT

Product: 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Products: NA

Alternate protein names: DHNA-octaprenyltransferase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNERNKSLWKQAIKWPLYSVAILPVFISGAYTLNSFKNIKISNLIAFTIAAILILIWENLTNDLFDSETGIDEFKFHSIV
NLVRSKKIISTIAYTSLLIGLLVIAIISISTSINVMILVVSCCFLGYLYQGPPFRLGYQGLGEPLCWLAFGPLTYSAALI
ALNPSDIYTITIPWKDSFLLGSGSSLATTLILFCSHFHQIEEDKKHGKNSPLVRLGPKKGAKLIPWIVFIVYFFQLFIII
NGFIPILCILFLISLPQSIKLITLLKSSYNKPEVIKNCKFIAVKFQTLNGIGLIAGLIIDYLINK

Sequences:

>Translated_305_residues
MNERNKSLWKQAIKWPLYSVAILPVFISGAYTLNSFKNIKISNLIAFTIAAILILIWENLTNDLFDSETGIDEFKFHSIV
NLVRSKKIISTIAYTSLLIGLLVIAIISISTSINVMILVVSCCFLGYLYQGPPFRLGYQGLGEPLCWLAFGPLTYSAALI
ALNPSDIYTITIPWKDSFLLGSGSSLATTLILFCSHFHQIEEDKKHGKNSPLVRLGPKKGAKLIPWIVFIVYFFQLFIII
NGFIPILCILFLISLPQSIKLITLLKSSYNKPEVIKNCKFIAVKFQTLNGIGLIAGLIIDYLINK
>Mature_305_residues
MNERNKSLWKQAIKWPLYSVAILPVFISGAYTLNSFKNIKISNLIAFTIAAILILIWENLTNDLFDSETGIDEFKFHSIV
NLVRSKKIISTIAYTSLLIGLLVIAIISISTSINVMILVVSCCFLGYLYQGPPFRLGYQGLGEPLCWLAFGPLTYSAALI
ALNPSDIYTITIPWKDSFLLGSGSSLATTLILFCSHFHQIEEDKKHGKNSPLVRLGPKKGAKLIPWIVFIVYFFQLFIII
NGFIPILCILFLISLPQSIKLITLLKSSYNKPEVIKNCKFIAVKFQTLNGIGLIAGLIIDYLINK

Specific function: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK). Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA. The conversion of DHNA to DMK proceeds in three stages:the removal of the carboxyl group of DHNA

COG id: COG1575

COG function: function code H; 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the menA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011937
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: =2.5.1.74 [H]

Molecular weight: Translated: 34099; Mature: 34099

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERNKSLWKQAIKWPLYSVAILPVFISGAYTLNSFKNIKISNLIAFTIAAILILIWENL
CCCCHHHHHHHHHHCHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
TNDLFDSETGIDEFKFHSIVNLVRSKKIISTIAYTSLLIGLLVIAIISISTSINVMILVV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SCCFLGYLYQGPPFRLGYQGLGEPLCWLAFGPLTYSAALIALNPSDIYTITIPWKDSFLL
HHHHHHHHHCCCCCEECHHCCCCCHHHHEECHHHHHEEEEEECCCCEEEEEECCCCCEEE
GSGSSLATTLILFCSHFHQIEEDKKHGKNSPLVRLGPKKGAKLIPWIVFIVYFFQLFIII
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
NGFIPILCILFLISLPQSIKLITLLKSSYNKPEVIKNCKFIAVKFQTLNGIGLIAGLIID
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHCCEEEEEEEECCCCHHHHHHHHHH
YLINK
HHHCC
>Mature Secondary Structure
MNERNKSLWKQAIKWPLYSVAILPVFISGAYTLNSFKNIKISNLIAFTIAAILILIWENL
CCCCHHHHHHHHHHCHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
TNDLFDSETGIDEFKFHSIVNLVRSKKIISTIAYTSLLIGLLVIAIISISTSINVMILVV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SCCFLGYLYQGPPFRLGYQGLGEPLCWLAFGPLTYSAALIALNPSDIYTITIPWKDSFLL
HHHHHHHHHCCCCCEECHHCCCCCHHHHEECHHHHHEEEEEECCCCEEEEEECCCCCEEE
GSGSSLATTLILFCSHFHQIEEDKKHGKNSPLVRLGPKKGAKLIPWIVFIVYFFQLFIII
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
NGFIPILCILFLISLPQSIKLITLLKSSYNKPEVIKNCKFIAVKFQTLNGIGLIAGLIID
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHCCEEEEEEEECCCCHHHHHHHHHH
YLINK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]