Click here to switch to the map view.

The map label for this gene is menC [H]

Identifier: 123965439

GI number: 123965439

Start: 186187

End: 187152

Strand: Reverse

Name: menC [H]

Synonym: P9515_02041

Alternate gene names: 123965439

Gene position: 187152-186187 (Counterclockwise)

Preceding gene: 123965440

Following gene: 123965438

Centisome position: 10.98

GC content: 27.54

Gene sequence:

>966_bases
ATGAACTTAACTTTTAAAAAAAAATCTTTTTTATTTAAATTATCTTCTAAGGTAGAAAATTCAAAGACAACATTTAAAAA
TAAATCTGGGTGGATAATTAAATTAAAAAATGTTGAGAAAGGTGTTGGTTTTGGGGAAGTAAATCCTTTAAGTAATAAAG
ATTTAGTTAAATGTCAAATAGAATTAAATAAGATTCCTAAATATATTAATTCAAAAAATATATCGGAACTGATAAATACC
TTTCACCCATGTATTCAATCAGCAATTAATTCTGCGTTAGCTGAAATCGAAAGAAAAATAATTTTCAAAGAAAATTATTT
CTTTAATGCAATTGATCAAACAGCTATACTTTTAAATCCTAATAACGCTTTGCAAGAATTAAAAAAATTGAAAGAGAATA
AACTATTAAAAGGGAAATTACTTACAATAAAATGGAAAGTAGCTATATATGACAATGCCTCTGAAGAAAAAACTCTAATT
CAGATATTAAATCAATTAACAAGTAATATTAAATTAAGAATAGATGCAAATGGCTCTTGGGAGAGGGGAATAGCGAATAG
ATGGGTAGATATTCTTAAAGATATTAAAAACATAGATTGGTTGGAACAACCTCTTTCTAAAGATGATATTGAGGGTTTAA
GGGAAATTAATAAAAGGATGCCCATAGCTTTGGATGAATCACTATTAAAATATCCACATTTGATTAATGAATGGGATGGT
TGGCAGATTAGAAGACCTTCCCAAGAAAAGAATCCGATGCATCTTTTAGAAGAGTTAAAAAATAAAAAAGGTTTTAGATC
CTTAAGTACTTCTTTTGAAACAGGAATAGGTAATAGATGGCTTTTTCATTTATCCTCTTTACAGTTATTGGGACCAACTC
CAAAAGTTCCTGGTTTGGCTTTAAAAAAAAATCCCAATTCTTTTCTTTTTCTAAATAAGGCACAAAAGATATGGGATCAA
CTATGA

Upstream 100 bases:

>100_bases
CTGAAGTAATAAAAAATTGTAAATTTATTGCGGTCAAATTTCAAACTCTAAATGGAATTGGATTAATAGCAGGATTAATT
ATTGATTACTTGATTAATAA

Downstream 100 bases:

>100_bases
AAAACAAAATTCATATTATTGAAGTTGAAAATAATGAAAAAGAATCTACGAAGAAAATTCTTAAAAACATTAAGGAAAAG
AAAATAATTTACATAAAAAA

Product: putative O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MNLTFKKKSFLFKLSSKVENSKTTFKNKSGWIIKLKNVEKGVGFGEVNPLSNKDLVKCQIELNKIPKYINSKNISELINT
FHPCIQSAINSALAEIERKIIFKENYFFNAIDQTAILLNPNNALQELKKLKENKLLKGKLLTIKWKVAIYDNASEEKTLI
QILNQLTSNIKLRIDANGSWERGIANRWVDILKDIKNIDWLEQPLSKDDIEGLREINKRMPIALDESLLKYPHLINEWDG
WQIRRPSQEKNPMHLLEELKNKKGFRSLSTSFETGIGNRWLFHLSSLQLLGPTPKVPGLALKKNPNSFLFLNKAQKIWDQ
L

Sequences:

>Translated_321_residues
MNLTFKKKSFLFKLSSKVENSKTTFKNKSGWIIKLKNVEKGVGFGEVNPLSNKDLVKCQIELNKIPKYINSKNISELINT
FHPCIQSAINSALAEIERKIIFKENYFFNAIDQTAILLNPNNALQELKKLKENKLLKGKLLTIKWKVAIYDNASEEKTLI
QILNQLTSNIKLRIDANGSWERGIANRWVDILKDIKNIDWLEQPLSKDDIEGLREINKRMPIALDESLLKYPHLINEWDG
WQIRRPSQEKNPMHLLEELKNKKGFRSLSTSFETGIGNRWLFHLSSLQLLGPTPKVPGLALKKNPNSFLFLNKAQKIWDQ
L
>Mature_321_residues
MNLTFKKKSFLFKLSSKVENSKTTFKNKSGWIIKLKNVEKGVGFGEVNPLSNKDLVKCQIELNKIPKYINSKNISELINT
FHPCIQSAINSALAEIERKIIFKENYFFNAIDQTAILLNPNNALQELKKLKENKLLKGKLLTIKWKVAIYDNASEEKTLI
QILNQLTSNIKLRIDANGSWERGIANRWVDILKDIKNIDWLEQPLSKDDIEGLREINKRMPIALDESLLKYPHLINEWDG
WQIRRPSQEKNPMHLLEELKNKKGFRSLSTSFETGIGNRWLFHLSSLQLLGPTPKVPGLALKKNPNSFLFLNKAQKIWDQ
L

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 37091; Mature: 37091

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTFKKKSFLFKLSSKVENSKTTFKNKSGWIIKLKNVEKGVGFGEVNPLSNKDLVKCQI
CCCCCCHHHHHHHHHHHHCCCHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEE
ELNKIPKYINSKNISELINTFHPCIQSAINSALAEIERKIIFKENYFFNAIDQTAILLNP
EHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCEEEEECC
NNALQELKKLKENKLLKGKLLTIKWKVAIYDNASEEKTLIQILNQLTSNIKLRIDANGSW
CHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCH
ERGIANRWVDILKDIKNIDWLEQPLSKDDIEGLREINKRMPIALDESLLKYPHLINEWDG
HHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
WQIRRPSQEKNPMHLLEELKNKKGFRSLSTSFETGIGNRWLFHLSSLQLLGPTPKVPGLA
CEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEHEEHHHHEECCCCCCCCEE
LKKNPNSFLFLNKAQKIWDQL
EECCCCCEEEECHHHHHHHCC
>Mature Secondary Structure
MNLTFKKKSFLFKLSSKVENSKTTFKNKSGWIIKLKNVEKGVGFGEVNPLSNKDLVKCQI
CCCCCCHHHHHHHHHHHHCCCHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEE
ELNKIPKYINSKNISELINTFHPCIQSAINSALAEIERKIIFKENYFFNAIDQTAILLNP
EHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCEEEEECC
NNALQELKKLKENKLLKGKLLTIKWKVAIYDNASEEKTLIQILNQLTSNIKLRIDANGSW
CHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCH
ERGIANRWVDILKDIKNIDWLEQPLSKDDIEGLREINKRMPIALDESLLKYPHLINEWDG
HHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
WQIRRPSQEKNPMHLLEELKNKKGFRSLSTSFETGIGNRWLFHLSSLQLLGPTPKVPGLA
CEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEHEEHHHHEECCCCCCCCEE
LKKNPNSFLFLNKAQKIWDQL
EECCCCCEEEECHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]