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The map label for this gene is hit [C]

Identifier: 123965311

GI number: 123965311

Start: 81019

End: 81360

Strand: Reverse

Name: hit [C]

Synonym: P9515_00761

Alternate gene names: 123965311

Gene position: 81360-81019 (Counterclockwise)

Preceding gene: 123965312

Following gene: 123965310

Centisome position: 4.77

GC content: 34.21

Gene sequence:

>342_bases
ATGACTCAAACCACAATCTTCAGCAAAATAATCAATGGTGAAATTCCCTGTGAAAAGCTTTATGAAGACGAGCTTTGTAT
AGCATTTGATGACATTGCCGCTCAAGCTCCAGTTCATTTTTTAGTAATTCCTAAAAAACCGCTAGTTAGTTTATATGAAT
GTTTAGAAGAGGATAAAGATTTATTAGGTCATCTTCTTTTGGTAGGAAAAAATATTGCTAGATCGAAGAAATTAAAGAAT
TGGAGAACAGTGATTAATACTGGGGAAGAATCCGGACAAACAGTATTTCATTTACATATACATTTTTTAGCCGGCAGAAA
AATGAGTTGGCCGCCAGGATAA

Upstream 100 bases:

>100_bases
AGTTACATCCAAAGAAGATTTAAAAACTGAACTAAAAAAAGAAGGATTCCAAATGAAAGATGTGTTTCCAATAAGTCAAT
CTTAATAATCAAAATTATTA

Downstream 100 bases:

>100_bases
AACTCTCAAAAAAGTTAATTTTTAGCTATAAGTAAGAATAAAAGAATATGAAGACTCCTGAATCTTTAAATAGTAAGCCT
AATAATTTCTTAAATCTAAT

Product: HIT (histidine triad) family protein

Products: NA

Alternate protein names: ORF 1 [H]

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MTQTTIFSKIINGEIPCEKLYEDELCIAFDDIAAQAPVHFLVIPKKPLVSLYECLEEDKDLLGHLLLVGKNIARSKKLKN
WRTVINTGEESGQTVFHLHIHFLAGRKMSWPPG

Sequences:

>Translated_113_residues
MTQTTIFSKIINGEIPCEKLYEDELCIAFDDIAAQAPVHFLVIPKKPLVSLYECLEEDKDLLGHLLLVGKNIARSKKLKN
WRTVINTGEESGQTVFHLHIHFLAGRKMSWPPG
>Mature_112_residues
TQTTIFSKIINGEIPCEKLYEDELCIAFDDIAAQAPVHFLVIPKKPLVSLYECLEEDKDLLGHLLLVGKNIARSKKLKNW
RTVINTGEESGQTVFHLHIHFLAGRKMSWPPG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI14211923, Length=110, Percent_Identity=54.5454545454545, Blast_Score=135, Evalue=9e-33,
Organism=Homo sapiens, GI4885413, Length=110, Percent_Identity=51.8181818181818, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1787346, Length=111, Percent_Identity=38.7387387387387, Blast_Score=84, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17506713, Length=113, Percent_Identity=42.4778761061947, Blast_Score=115, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6320078, Length=112, Percent_Identity=33.9285714285714, Blast_Score=60, Evalue=9e-11,
Organism=Drosophila melanogaster, GI28574010, Length=113, Percent_Identity=53.0973451327434, Blast_Score=139, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24581222, Length=113, Percent_Identity=53.0973451327434, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 12800; Mature: 12669

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTTIFSKIINGEIPCEKLYEDELCIAFDDIAAQAPVHFLVIPKKPLVSLYECLEEDKD
CCCHHHHHHHHCCCCCHHHHCCCCEEEEECCHHCCCCEEEEEECCCHHHHHHHHHHHHHH
LLGHLLLVGKNIARSKKLKNWRTVINTGEESGQTVFHLHIHFLAGRKMSWPPG
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TQTTIFSKIINGEIPCEKLYEDELCIAFDDIAAQAPVHFLVIPKKPLVSLYECLEEDKD
CCHHHHHHHHCCCCCHHHHCCCCEEEEECCHHCCCCEEEEEECCCHHHHHHHHHHHHHH
LLGHLLLVGKNIARSKKLKNWRTVINTGEESGQTVFHLHIHFLAGRKMSWPPG
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2108129; 1472710 [H]