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The map label for this gene is coaE [H]

Identifier: 123965291

GI number: 123965291

Start: 61761

End: 62375

Strand: Reverse

Name: coaE [H]

Synonym: P9515_00561

Alternate gene names: 123965291

Gene position: 62375-61761 (Counterclockwise)

Preceding gene: 123965293

Following gene: 123965289

Centisome position: 3.66

GC content: 26.83

Gene sequence:

>615_bases
ATGAGCATCCAACAAAAATTAATAAAGAATCAGAGAAGGATAGGTCTTACTGGAGGAATTGCAAGTGGAAAATCTACAAT
AGCTAACTACATAAAAAACTATAAAGGTATTCCAATATTGGATGCTGATGAATATTCAAAAGAACTAATCAAGCCTACAA
GTAACAGCTATAAAAAAATTTTAGAATATTTTGGACATCAAATAGTTGATAATTATTCTTCTGAGAAAGAAATAAACAGG
CAATTATTAAAAAAAATCATTTTCAACGATTCTATACATAGGAAATGGATTCAGAATCTTCTTCATCCACTGATTAAAGA
AAAAATGATAGAAAAATGTAATCAATTTGGAAAGAATAAAATTTTACTTTTAGTTATCCCTTTACTATTTGAGGCGAAAT
TTACGGATTTATGTAGTGAAATATGGTTAGTAAGTTGTCCAAGAGAAATCCAAAAGAAAAGACTTATGAAGAGGGATAAT
ATAGAAAATAATGAGGCTGAAAAAATTATAAATCTTCAATTTAATTTTGAAGATAAATCCAAACTATCAAATGTAATTTT
AGACAATTCAAAAGATCAAAAGTTGTGGATAAAGACAATACAAAAGCTTCTCTAG

Upstream 100 bases:

>100_bases
ACCAATTAGTGTCAAACTGACTCAATTTTCTCAATAAATTAAACCTATACTAACTATTCTGTAGATATAAAACACAGCAA
TACAGATTCTTATTAAATTT

Downstream 100 bases:

>100_bases
AAATTAACTATTTAATTTTTCCGCAAGAAGTTTATTAGCAAGTTTGGGATCTACTTTACCTTTAGTTTTTTTCATAAGCT
GTCCTACAAAAAAACCAAGA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSIQQKLIKNQRRIGLTGGIASGKSTIANYIKNYKGIPILDADEYSKELIKPTSNSYKKILEYFGHQIVDNYSSEKEINR
QLLKKIIFNDSIHRKWIQNLLHPLIKEKMIEKCNQFGKNKILLLVIPLLFEAKFTDLCSEIWLVSCPREIQKKRLMKRDN
IENNEAEKIINLQFNFEDKSKLSNVILDNSKDQKLWIKTIQKLL

Sequences:

>Translated_204_residues
MSIQQKLIKNQRRIGLTGGIASGKSTIANYIKNYKGIPILDADEYSKELIKPTSNSYKKILEYFGHQIVDNYSSEKEINR
QLLKKIIFNDSIHRKWIQNLLHPLIKEKMIEKCNQFGKNKILLLVIPLLFEAKFTDLCSEIWLVSCPREIQKKRLMKRDN
IENNEAEKIINLQFNFEDKSKLSNVILDNSKDQKLWIKTIQKLL
>Mature_203_residues
SIQQKLIKNQRRIGLTGGIASGKSTIANYIKNYKGIPILDADEYSKELIKPTSNSYKKILEYFGHQIVDNYSSEKEINRQ
LLKKIIFNDSIHRKWIQNLLHPLIKEKMIEKCNQFGKNKILLLVIPLLFEAKFTDLCSEIWLVSCPREIQKKRLMKRDNI
ENNEAEKIINLQFNFEDKSKLSNVILDNSKDQKLWIKTIQKLL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=182, Percent_Identity=31.8681318681319, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI191252795, Length=182, Percent_Identity=31.8681318681319, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI110227607, Length=180, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI205277394, Length=180, Percent_Identity=26.1111111111111, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227605, Length=180, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227603, Length=180, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227601, Length=180, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1786292, Length=176, Percent_Identity=30.1136363636364, Blast_Score=99, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17554944, Length=178, Percent_Identity=30.3370786516854, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25143409, Length=174, Percent_Identity=28.1609195402299, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=179, Percent_Identity=30.7262569832402, Blast_Score=105, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24644728, Length=179, Percent_Identity=32.4022346368715, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24658602, Length=193, Percent_Identity=26.9430051813472, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23949; Mature: 23818

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQQKLIKNQRRIGLTGGIASGKSTIANYIKNYKGIPILDADEYSKELIKPTSNSYKKI
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHH
LEYFGHQIVDNYSSEKEINRQLLKKIIFNDSIHRKWIQNLLHPLIKEKMIEKCNQFGKNK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ILLLVIPLLFEAKFTDLCSEIWLVSCPREIQKKRLMKRDNIENNEAEKIINLQFNFEDKS
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHEEEEEECCCHHH
KLSNVILDNSKDQKLWIKTIQKLL
HHHHHHHCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
SIQQKLIKNQRRIGLTGGIASGKSTIANYIKNYKGIPILDADEYSKELIKPTSNSYKKI
CHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHH
LEYFGHQIVDNYSSEKEINRQLLKKIIFNDSIHRKWIQNLLHPLIKEKMIEKCNQFGKNK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ILLLVIPLLFEAKFTDLCSEIWLVSCPREIQKKRLMKRDNIENNEAEKIINLQFNFEDKS
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHEEEEEECCCHHH
KLSNVILDNSKDQKLWIKTIQKLL
HHHHHHHCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]