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The map label for this gene is mraY [H]

Identifier: 123969451

GI number: 123969451

Start: 1658851

End: 1659672

Strand: Direct

Name: mraY [H]

Synonym: A9601_19191

Alternate gene names: 123969451

Gene position: 1658851-1659672 (Clockwise)

Preceding gene: 123969450

Following gene: 123969455

Centisome position: 99.34

GC content: 27.25

Gene sequence:

>822_bases
ATGATAATCCCTTTTTTAATTTTGCTTTTGATAATAACTATCAACTTAAGTTCTCTAAAATTATTTCTATTGTTACTTAC
TATTTTTGGTTTCTTTATTACAGGATTTTTAGATGATTTATTAAGCATTAAAAAAAAAGAGAACACAGGTTTAAAAACAA
AAGAGAAATTTTTCATACAAAGTCTCATCTCAATAATTTTTATATTGTTAGCCTATGAAAAAATTTTAATCAGTCCATTA
ATAACAGTTTCTGACACCTGGGGAATAAATATGAATATTTTCATATTGCCAGTTTCTTTTTTAGTACTTGTGGGCTTAAG
TAATTCAGTAAATTTGACTGATGGACTGGATGGATTAGCAGCTGGATGCAGTGGGATTGTCTTTTATGGATTAGGAACAG
AAATATTAATGAAAGAACAGCAAGAACTTTATGTTTATAGCATCTTATGTTTTTCGATGTCCGGCATATGCTTAGGATTT
CTCAAGTATAATTATTATCCTGCAAAAATATTTATGGGTGACACAGGATCTCTAAGTATTGGAGCAATTATGGGTTCTAT
AGCGTTATTAACCAATAGCATTTTTACGCTATCTATTTTCTCAGGAATATTTATTGTTGAATCATTATCAGTAATAATAC
AAGTAGGATTTTTTAAAATTACTAAAAAATTATTTCATAAAGGTAAACGAATATTTTTAATGGCTCCACTACACCACCAT
TTTGAACTAAAAGGAGTTAAGGAACAAAAAATAGTTGAAAATTTTTGGAAAATCAACATTTTACTTGTAATTTTAGGTAT
AGTTTTAAAAATCAACCTTTGA

Upstream 100 bases:

>100_bases
AAAGATTATCAAAAAATTTAATTTACTTCAAAATATCAGGAATGAAGGCCCAGCTAATCACTTTAAAAAAAGTGATACTC
CAACAATGGGTGGGATTTTT

Downstream 100 bases:

>100_bases
AAAATTTGTTATGAATTTTTTTACATGGAAAGATAATGGATTAACAAGTGACTGCTCAAGTCTTGATGCAATGGCATCAA
GATTTGAAGAAACTGCTAAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MIIPFLILLLIITINLSSLKLFLLLLTIFGFFITGFLDDLLSIKKKENTGLKTKEKFFIQSLISIIFILLAYEKILISPL
ITVSDTWGINMNIFILPVSFLVLVGLSNSVNLTDGLDGLAAGCSGIVFYGLGTEILMKEQQELYVYSILCFSMSGICLGF
LKYNYYPAKIFMGDTGSLSIGAIMGSIALLTNSIFTLSIFSGIFIVESLSVIIQVGFFKITKKLFHKGKRIFLMAPLHHH
FELKGVKEQKIVENFWKINILLVILGIVLKINL

Sequences:

>Translated_273_residues
MIIPFLILLLIITINLSSLKLFLLLLTIFGFFITGFLDDLLSIKKKENTGLKTKEKFFIQSLISIIFILLAYEKILISPL
ITVSDTWGINMNIFILPVSFLVLVGLSNSVNLTDGLDGLAAGCSGIVFYGLGTEILMKEQQELYVYSILCFSMSGICLGF
LKYNYYPAKIFMGDTGSLSIGAIMGSIALLTNSIFTLSIFSGIFIVESLSVIIQVGFFKITKKLFHKGKRIFLMAPLHHH
FELKGVKEQKIVENFWKINILLVILGIVLKINL
>Mature_273_residues
MIIPFLILLLIITINLSSLKLFLLLLTIFGFFITGFLDDLLSIKKKENTGLKTKEKFFIQSLISIIFILLAYEKILISPL
ITVSDTWGINMNIFILPVSFLVLVGLSNSVNLTDGLDGLAAGCSGIVFYGLGTEILMKEQQELYVYSILCFSMSGICLGF
LKYNYYPAKIFMGDTGSLSIGAIMGSIALLTNSIFTLSIFSGIFIVESLSVIIQVGFFKITKKLFHKGKRIFLMAPLHHH
FELKGVKEQKIVENFWKINILLVILGIVLKINL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=259, Percent_Identity=38.996138996139, Blast_Score=164, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 30495; Mature: 30495

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIPFLILLLIITINLSSLKLFLLLLTIFGFFITGFLDDLLSIKKKENTGLKTKEKFFIQ
CHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
SLISIIFILLAYEKILISPLITVSDTWGINMNIFILPVSFLVLVGLSNSVNLTDGLDGLA
HHHHHHHHHHHHHHHHHCCHHEEECCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCHHHH
AGCSGIVFYGLGTEILMKEQQELYVYSILCFSMSGICLGFLKYNYYPAKIFMGDTGSLSI
HCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHH
GAIMGSIALLTNSIFTLSIFSGIFIVESLSVIIQVGFFKITKKLFHKGKRIFLMAPLHHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
FELKGVKEQKIVENFWKINILLVILGIVLKINL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIPFLILLLIITINLSSLKLFLLLLTIFGFFITGFLDDLLSIKKKENTGLKTKEKFFIQ
CHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
SLISIIFILLAYEKILISPLITVSDTWGINMNIFILPVSFLVLVGLSNSVNLTDGLDGLA
HHHHHHHHHHHHHHHHHCCHHEEECCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCHHHH
AGCSGIVFYGLGTEILMKEQQELYVYSILCFSMSGICLGFLKYNYYPAKIFMGDTGSLSI
HCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHH
GAIMGSIALLTNSIFTLSIFSGIFIVESLSVIIQVGFFKITKKLFHKGKRIFLMAPLHHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
FELKGVKEQKIVENFWKINILLVILGIVLKINL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA