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The map label for this gene is ubiB [C]

Identifier: 123969455

GI number: 123969455

Start: 1666179

End: 1668035

Strand: Direct

Name: ubiB [C]

Synonym: A9601_19231

Alternate gene names: 123969455

Gene position: 1666179-1668035 (Clockwise)

Preceding gene: 123969451

Following gene: 123969456

Centisome position: 99.78

GC content: 31.72

Gene sequence:

>1857_bases
ATGAAAGAAGACTTTACTGATTTTATTGAGGTATCTGGACTCTTAAATTATGATCCAGATACAATTTCTAAAATTTACAA
AAAAAATCCTAAAAGACTTTTAAAAAGGCTTTGGCAAACACTCCTACCTATTTTTGCTTACATCTTTTCCGTTGGATGGG
ATAAATTAACTGGAAGGCTGAAAAATAAACAGCAAGCAAGATTTAGAGCAAGAGAATTAACAAATTTGTTAGTAGAACTT
GGACCTGCATTTGTTAAAGCAGGCCAAGCTTTATCAACAAGACCAGATATAATCCCAGGCATTCTTCTAGAAGAATTATC
TGAATTGCAAGATCAGCTCCCAGGTTTTGATAGCGATAAAGCTATGGAATTAATAGAAGAAGATTTAGGAAACAAAATAG
ATGAGATTTTTTTAGAAATTGATAAAGAGCCAATTTCTGCTGCTTCTTTAGGTCAAGTACATAAAGCTAAATTAAAAAAC
GAAGAGATCGTTGCAATAAAAGTACAAAGGCCAGGTTTAAGAGAACAAATAACCTTAGACCTTTACATTGTAAGAAATAT
TGCTTATTGGCTAAAAAACAATATCGGATTGATAAGAAGTGATCTAGTTGCTTTGATTGATGAATTAGGCAAGAGGGTTT
TTGAAGAAATGGATTATTTAAACGAAGCTGCAAATGCAGAAAAATTTAGAGATATGCATAAACATAACAAGATGATTGCC
GTACCAAAAATTTATAAAGAAATAACTTCAAGAAGAGTTTTAGCAATGGAATGGATAGACGGTACAAAATTAACAAATTT
AGAGGATGTAAAAAAATTAGGAATTAATCCTGATGACATGATTGATATAGGGGTGCAATGCAGTTTAGAACAGCTTTTAG
AACATGGTTTTTTTCATGCAGACCCGCATCCAGGTAATTTATTAGCCTTAGAAGATGGAAGATTATGTTATCTAGATTTT
GGAATGATGAGCGAGGTTTCCAGAGAATCTAGGTCAGGATTAATTCAAGCAGTAGTTCACTTAGTAAATAAAAACTTCGA
TAAATTGTCTCAAGATTTCGTAAAATTAGGATTTTTATCAGAGGAAGTTAATCTAGAACCTATTGTTCCAGCATTTCAAG
ATGTTTTCATTAACGCCGTTGAACAAGGAGTTTCGAAAATGGATTTTAAGAGCGTTACTGACGATATGTCTGGTGTTATG
TATAAATTCCCTTTCAGACTACCCCCGTATTATGCTCTTATAATTAGATCATTACTTACATTAGAGGGAATAGCTTTAAG
CGTAGATCCAAACTTCAAAATATTAGGAGCAGCTTATCCATATTTTGCAAGAAGATTGATGGAAGACCCTGATCCACAAT
TGAGGGAAAGCCTTAAAGAAATGCTTTTTGATAATAAAAAATTTAAATGGGATCGTTTAGAAGATCTACTTTCTAACGCT
GCAAAGCAAACAAATCTCGATTTAGAAAAACTTTTAGACGAAGTTATAAATCTTCTCTTTTCTCCAACTGGAGGATTTCT
TAGAAATGAGATAGTTGAAGGTTTAACAAATCAGATAGATTTACTTAGTCTAAAAATATTGAAAAGTTTAAATAATTATC
TTCCACAATCAATTAAATTAAATACTACTAACGAAAATAATAACTTGAGTGACCTTATAATGTATGTTGAGCCATTGAGA
AACTTTTTAGAGATTTTACAAAAAGTACCGGGGTATTCAATTGACATTTTTCTAAGAAGAGTGCCAAGACTTATTAATGA
GCCCTATACAAAAGAAATGGGTATAAAAATAGCAAAAAAAGTAACTGAAAAAGGAGTAGTAAGACTTGTTAAGATTGCCG
CTGGTGCAAATATATAA

Upstream 100 bases:

>100_bases
GCAATATTTTCTATTTTTAGTTGTATTAACATGATAAATCTTCCATATAAAAAAATTAACTTCTTTTTTAAAAAAATAAA
GGTTTTAAATATATAAAGTT

Downstream 100 bases:

>100_bases
ATGAAGTTTAATAAATTTTTAAAATTAAAAATATTTTTTATTGTAGTAATTTCTCCATTATTTTTTAATATACCAAAAGC
TTGTACTGCTGAAGAAATTA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MKEDFTDFIEVSGLLNYDPDTISKIYKKNPKRLLKRLWQTLLPIFAYIFSVGWDKLTGRLKNKQQARFRARELTNLLVEL
GPAFVKAGQALSTRPDIIPGILLEELSELQDQLPGFDSDKAMELIEEDLGNKIDEIFLEIDKEPISAASLGQVHKAKLKN
EEIVAIKVQRPGLREQITLDLYIVRNIAYWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAANAEKFRDMHKHNKMIA
VPKIYKEITSRRVLAMEWIDGTKLTNLEDVKKLGINPDDMIDIGVQCSLEQLLEHGFFHADPHPGNLLALEDGRLCYLDF
GMMSEVSRESRSGLIQAVVHLVNKNFDKLSQDFVKLGFLSEEVNLEPIVPAFQDVFINAVEQGVSKMDFKSVTDDMSGVM
YKFPFRLPPYYALIIRSLLTLEGIALSVDPNFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
AKQTNLDLEKLLDEVINLLFSPTGGFLRNEIVEGLTNQIDLLSLKILKSLNNYLPQSIKLNTTNENNNLSDLIMYVEPLR
NFLEILQKVPGYSIDIFLRRVPRLINEPYTKEMGIKIAKKVTEKGVVRLVKIAAGANI

Sequences:

>Translated_618_residues
MKEDFTDFIEVSGLLNYDPDTISKIYKKNPKRLLKRLWQTLLPIFAYIFSVGWDKLTGRLKNKQQARFRARELTNLLVEL
GPAFVKAGQALSTRPDIIPGILLEELSELQDQLPGFDSDKAMELIEEDLGNKIDEIFLEIDKEPISAASLGQVHKAKLKN
EEIVAIKVQRPGLREQITLDLYIVRNIAYWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAANAEKFRDMHKHNKMIA
VPKIYKEITSRRVLAMEWIDGTKLTNLEDVKKLGINPDDMIDIGVQCSLEQLLEHGFFHADPHPGNLLALEDGRLCYLDF
GMMSEVSRESRSGLIQAVVHLVNKNFDKLSQDFVKLGFLSEEVNLEPIVPAFQDVFINAVEQGVSKMDFKSVTDDMSGVM
YKFPFRLPPYYALIIRSLLTLEGIALSVDPNFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
AKQTNLDLEKLLDEVINLLFSPTGGFLRNEIVEGLTNQIDLLSLKILKSLNNYLPQSIKLNTTNENNNLSDLIMYVEPLR
NFLEILQKVPGYSIDIFLRRVPRLINEPYTKEMGIKIAKKVTEKGVVRLVKIAAGANI
>Mature_618_residues
MKEDFTDFIEVSGLLNYDPDTISKIYKKNPKRLLKRLWQTLLPIFAYIFSVGWDKLTGRLKNKQQARFRARELTNLLVEL
GPAFVKAGQALSTRPDIIPGILLEELSELQDQLPGFDSDKAMELIEEDLGNKIDEIFLEIDKEPISAASLGQVHKAKLKN
EEIVAIKVQRPGLREQITLDLYIVRNIAYWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAANAEKFRDMHKHNKMIA
VPKIYKEITSRRVLAMEWIDGTKLTNLEDVKKLGINPDDMIDIGVQCSLEQLLEHGFFHADPHPGNLLALEDGRLCYLDF
GMMSEVSRESRSGLIQAVVHLVNKNFDKLSQDFVKLGFLSEEVNLEPIVPAFQDVFINAVEQGVSKMDFKSVTDDMSGVM
YKFPFRLPPYYALIIRSLLTLEGIALSVDPNFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
AKQTNLDLEKLLDEVINLLFSPTGGFLRNEIVEGLTNQIDLLSLKILKSLNNYLPQSIKLNTTNENNNLSDLIMYVEPLR
NFLEILQKVPGYSIDIFLRRVPRLINEPYTKEMGIKIAKKVTEKGVVRLVKIAAGANI

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=304, Percent_Identity=29.6052631578947, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI41393593, Length=263, Percent_Identity=30.4182509505703, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI217035081, Length=234, Percent_Identity=29.9145299145299, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI27363457, Length=324, Percent_Identity=29.320987654321, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI34147522, Length=299, Percent_Identity=30.1003344481605, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI217416386, Length=288, Percent_Identity=29.5138888888889, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI2367309, Length=407, Percent_Identity=27.5184275184275, Blast_Score=174, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17559152, Length=276, Percent_Identity=34.4202898550725, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32565180, Length=316, Percent_Identity=25.9493670886076, Blast_Score=80, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323282, Length=238, Percent_Identity=35.2941176470588, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6325148, Length=436, Percent_Identity=23.8532110091743, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321319, Length=256, Percent_Identity=28.125, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24662575, Length=269, Percent_Identity=34.2007434944238, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI22024280, Length=260, Percent_Identity=31.9230769230769, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI18859849, Length=260, Percent_Identity=28.4615384615385, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 70620; Mature: 70620

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEDFTDFIEVSGLLNYDPDTISKIYKKNPKRLLKRLWQTLLPIFAYIFSVGWDKLTGRL
CCCHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
KNKQQARFRARELTNLLVELGPAFVKAGQALSTRPDIIPGILLEELSELQDQLPGFDSDK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
AMELIEEDLGNKIDEIFLEIDKEPISAASLGQVHKAKLKNEEIVAIKVQRPGLREQITLD
HHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LYIVRNIAYWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAANAEKFRDMHKHNKMIA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEE
VPKIYKEITSRRVLAMEWIDGTKLTNLEDVKKLGINPDDMIDIGVQCSLEQLLEHGFFHA
HHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCCCCCHHEECCHHHHHHHHHHCCCCCC
DPHPGNLLALEDGRLCYLDFGMMSEVSRESRSGLIQAVVHLVNKNFDKLSQDFVKLGFLS
CCCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EEVNLEPIVPAFQDVFINAVEQGVSKMDFKSVTDDMSGVMYKFPFRLPPYYALIIRSLLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHH
LEGIALSVDPNFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
HCCEEEEECCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AKQTNLDLEKLLDEVINLLFSPTGGFLRNEIVEGLTNQIDLLSLKILKSLNNYLPQSIKL
HHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
NTTNENNNLSDLIMYVEPLRNFLEILQKVPGYSIDIFLRRVPRLINEPYTKEMGIKIAKK
ECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
VTEKGVVRLVKIAAGANI
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKEDFTDFIEVSGLLNYDPDTISKIYKKNPKRLLKRLWQTLLPIFAYIFSVGWDKLTGRL
CCCHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
KNKQQARFRARELTNLLVELGPAFVKAGQALSTRPDIIPGILLEELSELQDQLPGFDSDK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
AMELIEEDLGNKIDEIFLEIDKEPISAASLGQVHKAKLKNEEIVAIKVQRPGLREQITLD
HHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LYIVRNIAYWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAANAEKFRDMHKHNKMIA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEE
VPKIYKEITSRRVLAMEWIDGTKLTNLEDVKKLGINPDDMIDIGVQCSLEQLLEHGFFHA
HHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCCCCCHHEECCHHHHHHHHHHCCCCCC
DPHPGNLLALEDGRLCYLDFGMMSEVSRESRSGLIQAVVHLVNKNFDKLSQDFVKLGFLS
CCCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EEVNLEPIVPAFQDVFINAVEQGVSKMDFKSVTDDMSGVMYKFPFRLPPYYALIIRSLLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHH
LEGIALSVDPNFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
HCCEEEEECCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AKQTNLDLEKLLDEVINLLFSPTGGFLRNEIVEGLTNQIDLLSLKILKSLNNYLPQSIKL
HHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
NTTNENNNLSDLIMYVEPLRNFLEILQKVPGYSIDIFLRRVPRLINEPYTKEMGIKIAKK
ECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
VTEKGVVRLVKIAAGANI
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]