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The map label for this gene is queC [H]

Identifier: 123969433

GI number: 123969433

Start: 1637422

End: 1638096

Strand: Direct

Name: queC [H]

Synonym: A9601_19011

Alternate gene names: 123969433

Gene position: 1637422-1638096 (Clockwise)

Preceding gene: 123969432

Following gene: 123969434

Centisome position: 98.06

GC content: 31.11

Gene sequence:

>675_bases
ATGACTCTTAAAAATAAATCGATAGTAGTTTTATTATCTGGAGGTTTAGATTCTTCTACAGTTACTGGTATCGCCAAAAA
ATCCGAAGCTAAAATTTTTGGCCTTTCATTTGACTACGGTCAACGTCATAAAAAAGAATTAAATTCTGCATCAATAATTG
CAAAACACTTTGATATCGACGAATTTAAAATCATTAAGCTTGACTTATCTTTATGGGGAGGCTCGTCATTAACTGATACT
CAAAAAAATATTCCAATAGAAGGAGTGCAAACTAATAAAATTCCTAATACTTATGTTCCTGGGAGAAATACTATATTTAT
TTCCGTTGCACTAAGTTATGCCGAAGCAATAGATGCTGATTTTATAGGACTAGGAGTTAATGCACTAGATTATTCTGGTT
ATCCAGATTGCAGGCCTGACTACATTAAAAAATTTCAAGAGTTAGCAGATTTAGCCAATAAAAGAGGAAGAGAAAATAAT
CCAATAAAACTTTGGACACCACTATTAGATTTAAATAAAGAGGAAATTATTAAATTAGCTTTTGATAATCATGTCCCTTT
AGATAAAACATGGAGTTGTTATTCGGGTAATTCAAAACCATGCGGTAAGTGTGATAGCTGCAGAATTAGAAATGCTGCTT
ATGAAAAATGGCTTAATAACAATAATAAAAAATGA

Upstream 100 bases:

>100_bases
TGCGAATGGTTTTTCTCTTGCTATTGATTTCGTAAAAAATAACCCCGATTGGAAATTGAGCCTTCAAACTCACAAATACT
TAAAAATTAATTGAAATCAT

Downstream 100 bases:

>100_bases
AAATAAAAAAAATAATTCTAGAAAAATGGATAGATCCAGCACTGATTACGCATCATCTAACAAAAAAATTTGGAGATCAA
GGATTAGCTTGGCTAGACAG

Product: ATPase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELNSASIIAKHFDIDEFKIIKLDLSLWGGSSLTDT
QKNIPIEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENN
PIKLWTPLLDLNKEEIIKLAFDNHVPLDKTWSCYSGNSKPCGKCDSCRIRNAAYEKWLNNNNKK

Sequences:

>Translated_224_residues
MTLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELNSASIIAKHFDIDEFKIIKLDLSLWGGSSLTDT
QKNIPIEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENN
PIKLWTPLLDLNKEEIIKLAFDNHVPLDKTWSCYSGNSKPCGKCDSCRIRNAAYEKWLNNNNKK
>Mature_223_residues
TLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELNSASIIAKHFDIDEFKIIKLDLSLWGGSSLTDTQ
KNIPIEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNP
IKLWTPLLDLNKEEIIKLAFDNHVPLDKTWSCYSGNSKPCGKCDSCRIRNAAYEKWLNNNNKK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=221, Percent_Identity=33.4841628959276, Blast_Score=121, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25022; Mature: 24891

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELNSASIIAKHFDID
CCCCCCEEEEEEECCCCCCHHHHECCCCCCEEEEEECCCCHHHHHHCCHHHEEEECCCCC
EFKIIKLDLSLWGGSSLTDTQKNIPIEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDAD
CEEEEEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEEEEEHHHHHHCCC
FIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNPIKLWTPLLDLNKEEIIKLA
EEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCHHHEEEEE
FDNHVPLDKTWSCYSGNSKPCGKCDSCRIRNAAYEKWLNNNNKK
ECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELNSASIIAKHFDID
CCCCCEEEEEEECCCCCCHHHHECCCCCCEEEEEECCCCHHHHHHCCHHHEEEECCCCC
EFKIIKLDLSLWGGSSLTDTQKNIPIEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDAD
CEEEEEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEEEEEHHHHHHCCC
FIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNPIKLWTPLLDLNKEEIIKLA
EEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCHHHEEEEE
FDNHVPLDKTWSCYSGNSKPCGKCDSCRIRNAAYEKWLNNNNKK
ECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA