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The map label for this gene is trpE2 [H]

Identifier: 123969434

GI number: 123969434

Start: 1638093

End: 1639406

Strand: Direct

Name: trpE2 [H]

Synonym: A9601_19021

Alternate gene names: 123969434

Gene position: 1638093-1639406 (Clockwise)

Preceding gene: 123969433

Following gene: 123969435

Centisome position: 98.1

GC content: 29.15

Gene sequence:

>1314_bases
ATGAAAATAAAAAAAATAATTCTAGAAAAATGGATAGATCCAGCACTGATTACGCATCATCTAACAAAAAAATTTGGAGA
TCAAGGATTAGCTTGGCTAGACAGCGATGGCAAAGAAAATGGGGAATGGTCAATAATAGGAATTAAACCTAAAAAAATAA
TCCAATCAAGAGATATCAATAACTTAGACAAAACTAATAATCCATTTAACAATTTAAGAAATATTGAAAAAGGATTTTGG
ATCGGATGGTTAAGTTATGAAGCCGGAGTTTACATAGAACCAAAAAACCCATGGAAAAAATCTAATATGGCAACTTTATG
GATTGCATCATATGATCCAATCATTAAATGTAATCTAATAAAAAAAGAAATAATTATCGAAGGCACAAACTCATCTGAAC
TGATGAATTATAAAAACATAATCAACAATATAAAAAATATCGAAGAAGAAAATATTATTAAAACAAAGTTGAATTTTGAT
TTTTCAAAAATAAATTTGGACGAAATGGCTGAAAAATTTCAGAAAAATATTTTAAAATTGAAAAAATTAATTTCCTTAGG
AGATATATTTCAAGCAAACCTAACAACTAAATGCGAAATTGAATCTTCCAAAAACTATAATCCTCTAGATATTTATTTGA
AAATAAGAAGGAAATTAAGAGCTCCCTTTGGAGGAATAATAATAAATAATAATTATAAAGAGGCTGTATTATCTACCTCG
CCAGAAAGGTTTTTAAAGATAGATAATAAAAATTTTGTAGAATCAAGACCTATCAAAGGAACTAGATCCAGAGATAAAGA
TTTAAATCAAGACGCACTTAATGCTATCGATTTAATAACTAATGAGAAAGATAGAGCCGAAAATATTATGATTGTTGACC
TAATAAGAAATGATTTAAGTAAAGTTTGCGAAACAGGAAGTATTATGGTGCCAGAAATATTAAAACTTGAAAGTTTCTTA
AAAGTTCATCATCTAACTTCAGTAATCAGAGGCAAATTAAAAAAAGACACGAACTGGATTGATTTACTAAAAGCTTGTTG
GCCTGGGGGCTCTATAACTGGAGCACCTAAATTAAGATCATGCCAGAGACTTTTTGAATTAGAAAAATGTGAACGCGGAC
CATACTGTGGGTCATTTTTGAAGCTTGACTGGAATGGAGAGTTTGACAGCAATATACTAATAAGATCATTTTTAGTTAAA
GACAAAAAAATCAATATATATGCTGGTTGCGGAATAGTTATTGACTCAGACCCGGAGGAAGAAACTGATGAACTAAAGTG
GAAACTTTTACCATTAATTGATTCACTAAAATGA

Upstream 100 bases:

>100_bases
GGAGTTGTTATTCGGGTAATTCAAAACCATGCGGTAAGTGTGATAGCTGCAGAATTAGAAATGCTGCTTATGAAAAATGG
CTTAATAACAATAATAAAAA

Downstream 100 bases:

>100_bases
TTGAAACATTAGGCTGGCACAAGGATCAATGGTTGGATATTGATAGAATATTTATTGCTGCTAATAATAGAGGATTAAAA
TTTGCAGATGGTATATTTGA

Product: putative p-aminobenzoate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKIKKIILEKWIDPALITHHLTKKFGDQGLAWLDSDGKENGEWSIIGIKPKKIIQSRDINNLDKTNNPFNNLRNIEKGFW
IGWLSYEAGVYIEPKNPWKKSNMATLWIASYDPIIKCNLIKKEIIIEGTNSSELMNYKNIINNIKNIEEENIIKTKLNFD
FSKINLDEMAEKFQKNILKLKKLISLGDIFQANLTTKCEIESSKNYNPLDIYLKIRRKLRAPFGGIIINNNYKEAVLSTS
PERFLKIDNKNFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLSKVCETGSIMVPEILKLESFL
KVHHLTSVIRGKLKKDTNWIDLLKACWPGGSITGAPKLRSCQRLFELEKCERGPYCGSFLKLDWNGEFDSNILIRSFLVK
DKKINIYAGCGIVIDSDPEEETDELKWKLLPLIDSLK

Sequences:

>Translated_437_residues
MKIKKIILEKWIDPALITHHLTKKFGDQGLAWLDSDGKENGEWSIIGIKPKKIIQSRDINNLDKTNNPFNNLRNIEKGFW
IGWLSYEAGVYIEPKNPWKKSNMATLWIASYDPIIKCNLIKKEIIIEGTNSSELMNYKNIINNIKNIEEENIIKTKLNFD
FSKINLDEMAEKFQKNILKLKKLISLGDIFQANLTTKCEIESSKNYNPLDIYLKIRRKLRAPFGGIIINNNYKEAVLSTS
PERFLKIDNKNFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLSKVCETGSIMVPEILKLESFL
KVHHLTSVIRGKLKKDTNWIDLLKACWPGGSITGAPKLRSCQRLFELEKCERGPYCGSFLKLDWNGEFDSNILIRSFLVK
DKKINIYAGCGIVIDSDPEEETDELKWKLLPLIDSLK
>Mature_437_residues
MKIKKIILEKWIDPALITHHLTKKFGDQGLAWLDSDGKENGEWSIIGIKPKKIIQSRDINNLDKTNNPFNNLRNIEKGFW
IGWLSYEAGVYIEPKNPWKKSNMATLWIASYDPIIKCNLIKKEIIIEGTNSSELMNYKNIINNIKNIEEENIIKTKLNFD
FSKINLDEMAEKFQKNILKLKKLISLGDIFQANLTTKCEIESSKNYNPLDIYLKIRRKLRAPFGGIIINNNYKEAVLSTS
PERFLKIDNKNFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLSKVCETGSIMVPEILKLESFL
KVHHLTSVIRGKLKKDTNWIDLLKACWPGGSITGAPKLRSCQRLFELEKCERGPYCGSFLKLDWNGEFDSNILIRSFLVK
DKKINIYAGCGIVIDSDPEEETDELKWKLLPLIDSLK

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=263, Percent_Identity=39.1634980988593, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI1787518, Length=265, Percent_Identity=32.4528301886792, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87082077, Length=193, Percent_Identity=30.0518134715026, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786809, Length=288, Percent_Identity=24.6527777777778, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=442, Percent_Identity=29.185520361991, Blast_Score=162, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6324361, Length=283, Percent_Identity=30.3886925795053, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR010118 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 50331; Mature: 50331

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKKIILEKWIDPALITHHLTKKFGDQGLAWLDSDGKENGEWSIIGIKPKKIIQSRDIN
CCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCHHHHHHHCCCC
NLDKTNNPFNNLRNIEKGFWIGWLSYEAGVYIEPKNPWKKSNMATLWIASYDPIIKCNLI
CCCCCCCCHHHHHHHCCCEEEEEEEECCCEEECCCCCCCCCCEEEEEEECCCCEEEEEEE
KKEIIIEGTNSSELMNYKNIINNIKNIEEENIIKTKLNFDFSKINLDEMAEKFQKNILKL
EEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCCHHHHHHHHHHHHHHH
KKLISLGDIFQANLTTKCEIESSKNYNPLDIYLKIRRKLRAPFGGIIINNNYKEAVLSTS
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHCCC
PERFLKIDNKNFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLS
CHHHEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCEEEHHHHHHHHH
KVCETGSIMVPEILKLESFLKVHHLTSVIRGKLKKDTNWIDLLKACWPGGSITGAPKLRS
HHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHH
CQRLFELEKCERGPYCGSFLKLDWNGEFDSNILIRSFLVKDKKINIYAGCGIVIDSDPEE
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECEEEECCCCCC
ETDELKWKLLPLIDSLK
CHHHHHHHEEHHHHCCC
>Mature Secondary Structure
MKIKKIILEKWIDPALITHHLTKKFGDQGLAWLDSDGKENGEWSIIGIKPKKIIQSRDIN
CCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCHHHHHHHCCCC
NLDKTNNPFNNLRNIEKGFWIGWLSYEAGVYIEPKNPWKKSNMATLWIASYDPIIKCNLI
CCCCCCCCHHHHHHHCCCEEEEEEEECCCEEECCCCCCCCCCEEEEEEECCCCEEEEEEE
KKEIIIEGTNSSELMNYKNIINNIKNIEEENIIKTKLNFDFSKINLDEMAEKFQKNILKL
EEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCCHHHHHHHHHHHHHHH
KKLISLGDIFQANLTTKCEIESSKNYNPLDIYLKIRRKLRAPFGGIIINNNYKEAVLSTS
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHCCC
PERFLKIDNKNFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLS
CHHHEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCEEEHHHHHHHHH
KVCETGSIMVPEILKLESFLKVHHLTSVIRGKLKKDTNWIDLLKACWPGGSITGAPKLRS
HHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHH
CQRLFELEKCERGPYCGSFLKLDWNGEFDSNILIRSFLVKDKKINIYAGCGIVIDSDPEE
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECEEEECCCCCC
ETDELKWKLLPLIDSLK
CHHHHHHHEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]