Click here to switch to the map view.

The map label for this gene is aspS [H]

Identifier: 123969430

GI number: 123969430

Start: 1633237

End: 1635033

Strand: Direct

Name: aspS [H]

Synonym: A9601_18981

Alternate gene names: 123969430

Gene position: 1633237-1635033 (Clockwise)

Preceding gene: 123969429

Following gene: 123969431

Centisome position: 97.81

GC content: 32.67

Gene sequence:

>1797_bases
ATGAGAAACAAAATTTGTGAAGAACTCAATAATACAGATATTGGTAAATTAGTTAATTTATGCGGATGGGTAGATAGAAG
AAGAGATCATGGTGGTGTAATTTTTATTGATTTAAGAGACCATAGTGGATTCCTACAAATAACAATTAACCCAGATGATG
GTGCAGATCTATTTAAACAGGCAGAAACTCTAAGAAATGAAACAGTAATAATGGTCAGCGGAATTATTAATGAAAGGCCC
AAAGATTCCATAAATACAAATTTAAGTACTGGAGAGTTAGAGCTTAAGGTTAAAGATTTGCAAATTCTCAACCAAATTAA
AAACAACTTACCTTTTCCAGTATCTATACATGATTATGAAAATACAAAAGAAGAACTCAGATTAAAATATAGATACCTTG
ATTTAAGAAGGGGAAAATTACTAGAAAATTTAAAAAAAAGACATAAGATTATTAAAGTTGCTAGAGAATTTCTTGATAAT
TTTGGATTTACAGAAGTAGAGACCCCATTACTTACAAAGTCAACTCCTGAAGGGGCTCGTGATTTTCTTGTTCCTGCACG
TCTTTCAAATGGAGAATTTTTTGCTTTACCTCAATCCCCACAACTCTTTAAACAACTTTTAATGGTTGGGGGCTTAGATA
AGTATTATCAAATCGCAAAATGTTTCCGTGATGAAGACTTAAGGGCAGATAGACAGCCAGAGTTTACTCAATTAGATATT
GAGATGAGCTTTATTAGTGAAGAAGAAATAATTTCTTTTAATGAAAGTCTCATAAAAAAAATATGGAAAGAAGTGTTAAA
TATTAATTTTAATAATGCTTTTCCAAGAATGACATGGCAGGCAGCAATGGATAATTACGGCACTGATAGACCAGATACTA
GATATCAAATGTTATTGAAAGATTTAGGAGGAGTATTAGGTAATATTGGATTTAATATTTTCACCAAAGCAATTAAGTCT
GGAGGGTATATAAAATCCATAACAGTCAAAGGAGGCAATTCAAGTATTAGCAATGTAAGAATTAAACCGGGAGGTGACAT
CTTCAAAGTAGCTCAAGACGCAGGAGCTGGTGGTTTAGCCTTTATAAGGGTCAAAGGAGATGAGCTTGAGACTATTGGGG
CAATTAAAAATAATTTAAGTGAAGAGCATATAGCTGATATTTTAAAAATCACAGAAGCAAAAGATGGAGACTTAATCCTC
TTAGGAGCTGGAGATAAACAAATTGTCAATCAGTCATTAGATAGGGTTAGACAATATATCGCAAAAGAATTAAATCTCAT
AGATAAAAGCAAATGGAATTTCTTATGGGTAACTGACTTCCCTATGTTTGAGAGAAATGAAGATGAAAATAGATATGAAG
CTTTACATCATCCTTTTTGTTCTCCAAAAAATATAAAATCTAAAGATTCTGAAAACTTGAAAAAAGAAATTGAGAGCTCT
ACAGCAAATGCTTATGACTTAGTTCTTAATGGATTAGAGTTAGGAGGTGGCTCTTTACGTATTCATGAGGCGAACCTACA
AAGACAGGTTCTGAAAACGGTAGGACTTACTGATAAAGAGATTGATGAAAAATTTGGATTTTTAATAGAAGCCTTAGAAA
TGGGGGCTCCTCCTCATGGTGGAATAGCGTTTGGATTGGATCGTATTACAATGCTGATCATTGGTGCAGATTCAATCAGA
GAAACCATTGCGTTTCCAAAAAATCAACAAGCAAAATGTCTTCTCACAAATGCACCTTCCAATGTCTCTGAATCACAATT
AAAAGAATTAGATATTGAAATAACAATTGATGAATAA

Upstream 100 bases:

>100_bases
AACGGGGTTATAACAAAAAGAGCGTTTTATAAAAAGAATTATTAACTAAATTTGCCCTTAAAGAATTATTATAAGTTATT
GATAAATAAACCATACTTAG

Downstream 100 bases:

>100_bases
GAATATATATGGATGTTCTAAAAGTTTTTTGTTTAAATAAAATATAAGGAGGCTGTGCTTAATTAAAAATATTTAATGTC
AAAATTTGTATTTGTCACTG

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MRNKICEELNNTDIGKLVNLCGWVDRRRDHGGVIFIDLRDHSGFLQITINPDDGADLFKQAETLRNETVIMVSGIINERP
KDSINTNLSTGELELKVKDLQILNQIKNNLPFPVSIHDYENTKEELRLKYRYLDLRRGKLLENLKKRHKIIKVAREFLDN
FGFTEVETPLLTKSTPEGARDFLVPARLSNGEFFALPQSPQLFKQLLMVGGLDKYYQIAKCFRDEDLRADRQPEFTQLDI
EMSFISEEEIISFNESLIKKIWKEVLNINFNNAFPRMTWQAAMDNYGTDRPDTRYQMLLKDLGGVLGNIGFNIFTKAIKS
GGYIKSITVKGGNSSISNVRIKPGGDIFKVAQDAGAGGLAFIRVKGDELETIGAIKNNLSEEHIADILKITEAKDGDLIL
LGAGDKQIVNQSLDRVRQYIAKELNLIDKSKWNFLWVTDFPMFERNEDENRYEALHHPFCSPKNIKSKDSENLKKEIESS
TANAYDLVLNGLELGGGSLRIHEANLQRQVLKTVGLTDKEIDEKFGFLIEALEMGAPPHGGIAFGLDRITMLIIGADSIR
ETIAFPKNQQAKCLLTNAPSNVSESQLKELDIEITIDE

Sequences:

>Translated_598_residues
MRNKICEELNNTDIGKLVNLCGWVDRRRDHGGVIFIDLRDHSGFLQITINPDDGADLFKQAETLRNETVIMVSGIINERP
KDSINTNLSTGELELKVKDLQILNQIKNNLPFPVSIHDYENTKEELRLKYRYLDLRRGKLLENLKKRHKIIKVAREFLDN
FGFTEVETPLLTKSTPEGARDFLVPARLSNGEFFALPQSPQLFKQLLMVGGLDKYYQIAKCFRDEDLRADRQPEFTQLDI
EMSFISEEEIISFNESLIKKIWKEVLNINFNNAFPRMTWQAAMDNYGTDRPDTRYQMLLKDLGGVLGNIGFNIFTKAIKS
GGYIKSITVKGGNSSISNVRIKPGGDIFKVAQDAGAGGLAFIRVKGDELETIGAIKNNLSEEHIADILKITEAKDGDLIL
LGAGDKQIVNQSLDRVRQYIAKELNLIDKSKWNFLWVTDFPMFERNEDENRYEALHHPFCSPKNIKSKDSENLKKEIESS
TANAYDLVLNGLELGGGSLRIHEANLQRQVLKTVGLTDKEIDEKFGFLIEALEMGAPPHGGIAFGLDRITMLIIGADSIR
ETIAFPKNQQAKCLLTNAPSNVSESQLKELDIEITIDE
>Mature_598_residues
MRNKICEELNNTDIGKLVNLCGWVDRRRDHGGVIFIDLRDHSGFLQITINPDDGADLFKQAETLRNETVIMVSGIINERP
KDSINTNLSTGELELKVKDLQILNQIKNNLPFPVSIHDYENTKEELRLKYRYLDLRRGKLLENLKKRHKIIKVAREFLDN
FGFTEVETPLLTKSTPEGARDFLVPARLSNGEFFALPQSPQLFKQLLMVGGLDKYYQIAKCFRDEDLRADRQPEFTQLDI
EMSFISEEEIISFNESLIKKIWKEVLNINFNNAFPRMTWQAAMDNYGTDRPDTRYQMLLKDLGGVLGNIGFNIFTKAIKS
GGYIKSITVKGGNSSISNVRIKPGGDIFKVAQDAGAGGLAFIRVKGDELETIGAIKNNLSEEHIADILKITEAKDGDLIL
LGAGDKQIVNQSLDRVRQYIAKELNLIDKSKWNFLWVTDFPMFERNEDENRYEALHHPFCSPKNIKSKDSENLKKEIESS
TANAYDLVLNGLELGGGSLRIHEANLQRQVLKTVGLTDKEIDEKFGFLIEALEMGAPPHGGIAFGLDRITMLIIGADSIR
ETIAFPKNQQAKCLLTNAPSNVSESQLKELDIEITIDE

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=607, Percent_Identity=39.0444810543657, Blast_Score=410, Evalue=1e-114,
Organism=Homo sapiens, GI5031815, Length=265, Percent_Identity=27.9245283018868, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI194272210, Length=265, Percent_Identity=27.9245283018868, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI45439306, Length=239, Percent_Identity=26.7782426778243, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI1788173, Length=599, Percent_Identity=47.4123539232053, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1789256, Length=299, Percent_Identity=27.4247491638796, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790571, Length=315, Percent_Identity=27.9365079365079, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32566633, Length=605, Percent_Identity=35.0413223140496, Blast_Score=326, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI71994340, Length=255, Percent_Identity=27.0588235294118, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17535927, Length=255, Percent_Identity=27.0588235294118, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17535925, Length=255, Percent_Identity=27.0588235294118, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551876, Length=311, Percent_Identity=23.7942122186495, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325153, Length=659, Percent_Identity=33.6874051593323, Blast_Score=292, Evalue=8e-80,
Organism=Saccharomyces cerevisiae, GI6321807, Length=257, Percent_Identity=28.4046692607004, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6323011, Length=250, Percent_Identity=26.4, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320242, Length=258, Percent_Identity=25.968992248062, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324256, Length=153, Percent_Identity=31.3725490196078, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24584738, Length=609, Percent_Identity=37.1100164203612, Blast_Score=380, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24640849, Length=255, Percent_Identity=28.6274509803922, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24640851, Length=255, Percent_Identity=28.6274509803922, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17136276, Length=248, Percent_Identity=29.4354838709677, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 67595; Mature: 67595

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNKICEELNNTDIGKLVNLCGWVDRRRDHGGVIFIDLRDHSGFLQITINPDDGADLFKQ
CCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHH
AETLRNETVIMVSGIINERPKDSINTNLSTGELELKVKDLQILNQIKNNLPFPVSIHDYE
HHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEECCCC
NTKEELRLKYRYLDLRRGKLLENLKKRHKIIKVAREFLDNFGFTEVETPLLTKSTPEGAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
DFLVPARLSNGEFFALPQSPQLFKQLLMVGGLDKYYQIAKCFRDEDLRADRQPEFTQLDI
HCEEEEEECCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE
EMSFISEEEIISFNESLIKKIWKEVLNINFNNAFPRMTWQAAMDNYGTDRPDTRYQMLLK
EEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHH
DLGGVLGNIGFNIFTKAIKSGGYIKSITVKGGNSSISNVRIKPGGDIFKVAQDAGAGGLA
HHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCCCEEHHHHCCCCCCEE
FIRVKGDELETIGAIKNNLSEEHIADILKITEAKDGDLILLGAGDKQIVNQSLDRVRQYI
EEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHH
AKELNLIDKSKWNFLWVTDFPMFERNEDENRYEALHHPFCSPKNIKSKDSENLKKEIESS
HHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHC
TANAYDLVLNGLELGGGSLRIHEANLQRQVLKTVGLTDKEIDEKFGFLIEALEMGAPPHG
CCCHHHHHEEEEEECCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
GIAFGLDRITMLIIGADSIRETIAFPKNQQAKCLLTNAPSNVSESQLKELDIEITIDE
CEEECHHHEEEEEECCHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHCCEEEEECC
>Mature Secondary Structure
MRNKICEELNNTDIGKLVNLCGWVDRRRDHGGVIFIDLRDHSGFLQITINPDDGADLFKQ
CCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHH
AETLRNETVIMVSGIINERPKDSINTNLSTGELELKVKDLQILNQIKNNLPFPVSIHDYE
HHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEECCCC
NTKEELRLKYRYLDLRRGKLLENLKKRHKIIKVAREFLDNFGFTEVETPLLTKSTPEGAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
DFLVPARLSNGEFFALPQSPQLFKQLLMVGGLDKYYQIAKCFRDEDLRADRQPEFTQLDI
HCEEEEEECCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE
EMSFISEEEIISFNESLIKKIWKEVLNINFNNAFPRMTWQAAMDNYGTDRPDTRYQMLLK
EEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHH
DLGGVLGNIGFNIFTKAIKSGGYIKSITVKGGNSSISNVRIKPGGDIFKVAQDAGAGGLA
HHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCCCEEHHHHCCCCCCEE
FIRVKGDELETIGAIKNNLSEEHIADILKITEAKDGDLILLGAGDKQIVNQSLDRVRQYI
EEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHH
AKELNLIDKSKWNFLWVTDFPMFERNEDENRYEALHHPFCSPKNIKSKDSENLKKEIESS
HHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHC
TANAYDLVLNGLELGGGSLRIHEANLQRQVLKTVGLTDKEIDEKFGFLIEALEMGAPPHG
CCCHHHHHEEEEEECCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
GIAFGLDRITMLIIGADSIRETIAFPKNQQAKCLLTNAPSNVSESQLKELDIEITIDE
CEEECHHHEEEEEECCHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA