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The map label for this gene is dnaX [H]

Identifier: 123969399

GI number: 123969399

Start: 1601690

End: 1603444

Strand: Direct

Name: dnaX [H]

Synonym: A9601_18671

Alternate gene names: 123969399

Gene position: 1601690-1603444 (Clockwise)

Preceding gene: 123969398

Following gene: 123969402

Centisome position: 95.92

GC content: 30.48

Gene sequence:

>1755_bases
ATGCCAAATATACATAAACCTTTTCATCAAAAATATAGACCAAACAACTTAGACGAACTGGTTGGGCAAAAATTTATATC
CATTACACTCAAACAGGCTCTACTAACAAAAAAAATTGCTCCTGCATATCTTTTTAATGGTCCAAGAGGCACTGGAAAAA
CATCAAGTGCAAGAATTTTTGCAAAATCTCTAAATTGCCAGGCATTCGACCAACCTACTATAACTCCTTGTTGTAAATGT
GACTTATGTAGACAAATTACAGAAGGGAGCGCTCTAGATATTATCGAGATTGATGCAGCATCAAATACAGGAGTAGAAAA
TATAAGAGAAATTATAGAAAGAGCGAGATTTGCTCCTACTCAAGCGAGATGGAAAGTCTATGTAATTGATGAATGTCATA
TGCTTTCAACGGCAGCTTCAAACGCGTTACTAAAAACTATTGAAGAACCGCCCTCAAGAGTTGTATTTATACTTGCGACA
ACAAATCCTGAGAGAGTATTAAATACAATAAAAAGTAGATGCCAAAAGTTTGATTTTAGAAGAATAAGCCCTAGTGATAT
TTTTCAACATTTATCAGAAATCTCCGAAAAAGAATCCATTAAGTACGAAGTTCAGGCGTTAAAAATGATTGCAAAAAGGT
CTAATGGAGGTATGAGAGATGCGCAAAGCCTCCTTGAACAATTGAATCTTTTACCAGAAGGGATAACAATTAACGGTATC
CAAAACCTCCTAGGAGAAGTATCAGAAAGTGAATTAACAAATCTGATTAAATCATTGGTTGAGAATAATCCAGAGTCATT
AATTGACACTTGCAACAAATTATATGATTCCGGAAACGAACCTCTTCAAATAATTATCGGATTGTTGAATATAACAAGAG
ATCTACTATTACACACTACTAATAACAAATATTCAGATCTTTATTATACCTCTGATGAATTTCGAGATGAGTTAGATAAA
ATCTCAAAAACAATTAATAAATCTAAAATAGTAAATTGGCATAATAATCTGAGAAATATTGAATATCAAATCAAATCAAG
TGATAATCCAAGGCTTTGGTTAGAAATACATTTAACTGGTCTTCTGGATAGTCAAGAGATAAATAGTTTGGAAAATAAAA
AAGAAAGTAAAAATAATACGACTGAGGAGCATGAAAGTAGAAAAAACATTCCAATTAATAAAGAAAATATTTCACATGAG
ATTCCAAAACCAAGTATCCAAGAAGAGATAACACACAAGGAATTGATCGAAAAAAAAGAGGAAAAATTAGAAAAATTTGA
AGTTCTTGAAAAAGAAAGTATTGAAAATATTTCTGAAAATAACCAAAATAATCCTCGATCAAATTTAAAAGATAAATGGG
AATTAATTCTTTCTAAAGTAGAGTTACCATCAACAAGAATGTTACTTTCACAACAAGCCGAACTTGAAAGTTTTGATTCG
GAGAAAATCACAATTGCATTATCTCCAAACTGGGAAAATATGATAAAAAGCAGAAAAGTTATAATTGAAGATACTGTAAA
AAAGATATTTGGAGATGGAATAATACTTAATTTTTCAACCAAACAATTAAATAAAAGTAACCCTACAAACACTCCAGAAA
TAACCCAAAATGAAGTAAATAATTTCCGACCAATAAAAAAAATAGAACCAAAAACTAATTCGACAACAAAAATTTCCAAC
GAGGAAACTTATGATGATAGTTCAAAAAATTTAGCAAATTTTTTTAATGGAGAAATTATAGACCTTGATGAATAG

Upstream 100 bases:

>100_bases
ACTACCTTCAGGATCAAAAAGAATCATTAAAGAGTCTGCATAAAATTATAGTTTAATTTTTTTAATTGAATCCCTAATTT
TTCTAATTAATGAAAAATAA

Downstream 100 bases:

>100_bases
ATTAAACTCCAGTATGAAGAGTCTTTCGCCAGAGTATCTTTTTAGGAAAAATAGACATCTTTATAGTTACCCAAGGGATT
ACTAAAAACCAATGTGATAA

Product: DNA polymerase, gamma and tau subunits

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MPNIHKPFHQKYRPNNLDELVGQKFISITLKQALLTKKIAPAYLFNGPRGTGKTSSARIFAKSLNCQAFDQPTITPCCKC
DLCRQITEGSALDIIEIDAASNTGVENIREIIERARFAPTQARWKVYVIDECHMLSTAASNALLKTIEEPPSRVVFILAT
TNPERVLNTIKSRCQKFDFRRISPSDIFQHLSEISEKESIKYEVQALKMIAKRSNGGMRDAQSLLEQLNLLPEGITINGI
QNLLGEVSESELTNLIKSLVENNPESLIDTCNKLYDSGNEPLQIIIGLLNITRDLLLHTTNNKYSDLYYTSDEFRDELDK
ISKTINKSKIVNWHNNLRNIEYQIKSSDNPRLWLEIHLTGLLDSQEINSLENKKESKNNTTEEHESRKNIPINKENISHE
IPKPSIQEEITHKELIEKKEEKLEKFEVLEKESIENISENNQNNPRSNLKDKWELILSKVELPSTRMLLSQQAELESFDS
EKITIALSPNWENMIKSRKVIIEDTVKKIFGDGIILNFSTKQLNKSNPTNTPEITQNEVNNFRPIKKIEPKTNSTTKISN
EETYDDSSKNLANFFNGEIIDLDE

Sequences:

>Translated_584_residues
MPNIHKPFHQKYRPNNLDELVGQKFISITLKQALLTKKIAPAYLFNGPRGTGKTSSARIFAKSLNCQAFDQPTITPCCKC
DLCRQITEGSALDIIEIDAASNTGVENIREIIERARFAPTQARWKVYVIDECHMLSTAASNALLKTIEEPPSRVVFILAT
TNPERVLNTIKSRCQKFDFRRISPSDIFQHLSEISEKESIKYEVQALKMIAKRSNGGMRDAQSLLEQLNLLPEGITINGI
QNLLGEVSESELTNLIKSLVENNPESLIDTCNKLYDSGNEPLQIIIGLLNITRDLLLHTTNNKYSDLYYTSDEFRDELDK
ISKTINKSKIVNWHNNLRNIEYQIKSSDNPRLWLEIHLTGLLDSQEINSLENKKESKNNTTEEHESRKNIPINKENISHE
IPKPSIQEEITHKELIEKKEEKLEKFEVLEKESIENISENNQNNPRSNLKDKWELILSKVELPSTRMLLSQQAELESFDS
EKITIALSPNWENMIKSRKVIIEDTVKKIFGDGIILNFSTKQLNKSNPTNTPEITQNEVNNFRPIKKIEPKTNSTTKISN
EETYDDSSKNLANFFNGEIIDLDE
>Mature_583_residues
PNIHKPFHQKYRPNNLDELVGQKFISITLKQALLTKKIAPAYLFNGPRGTGKTSSARIFAKSLNCQAFDQPTITPCCKCD
LCRQITEGSALDIIEIDAASNTGVENIREIIERARFAPTQARWKVYVIDECHMLSTAASNALLKTIEEPPSRVVFILATT
NPERVLNTIKSRCQKFDFRRISPSDIFQHLSEISEKESIKYEVQALKMIAKRSNGGMRDAQSLLEQLNLLPEGITINGIQ
NLLGEVSESELTNLIKSLVENNPESLIDTCNKLYDSGNEPLQIIIGLLNITRDLLLHTTNNKYSDLYYTSDEFRDELDKI
SKTINKSKIVNWHNNLRNIEYQIKSSDNPRLWLEIHLTGLLDSQEINSLENKKESKNNTTEEHESRKNIPINKENISHEI
PKPSIQEEITHKELIEKKEEKLEKFEVLEKESIENISENNQNNPRSNLKDKWELILSKVELPSTRMLLSQQAELESFDSE
KITIALSPNWENMIKSRKVIIEDTVKKIFGDGIILNFSTKQLNKSNPTNTPEITQNEVNNFRPIKKIEPKTNSTTKISNE
ETYDDSSKNLANFFNGEIIDLDE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506491, Length=290, Percent_Identity=26.551724137931, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI31881687, Length=290, Percent_Identity=26.551724137931, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI6677723, Length=254, Percent_Identity=26.7716535433071, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI194306571, Length=251, Percent_Identity=26.6932270916335, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI194306567, Length=251, Percent_Identity=26.6932270916335, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI31563534, Length=294, Percent_Identity=23.1292517006803, Blast_Score=80, Evalue=7e-15,
Organism=Escherichia coli, GI1786676, Length=355, Percent_Identity=34.3661971830986, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1787119, Length=320, Percent_Identity=26.5625, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71986063, Length=286, Percent_Identity=25.1748251748252, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17541988, Length=344, Percent_Identity=24.7093023255814, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17554730, Length=231, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322528, Length=328, Percent_Identity=26.5243902439024, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324039, Length=302, Percent_Identity=25.4966887417219, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324478, Length=220, Percent_Identity=25.4545454545455, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17647857, Length=292, Percent_Identity=22.6027397260274, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18859927, Length=274, Percent_Identity=28.4671532846715, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19921076, Length=268, Percent_Identity=23.8805970149254, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 66781; Mature: 66649

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNIHKPFHQKYRPNNLDELVGQKFISITLKQALLTKKIAPAYLFNGPRGTGKTSSARIF
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCEEE
AKSLNCQAFDQPTITPCCKCDLCRQITEGSALDIIEIDAASNTGVENIREIIERARFAPT
EECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
QARWKVYVIDECHMLSTAASNALLKTIEEPPSRVVFILATTNPERVLNTIKSRCQKFDFR
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
RISPSDIFQHLSEISEKESIKYEVQALKMIAKRSNGGMRDAQSLLEQLNLLPEGITINGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEHHH
QNLLGEVSESELTNLIKSLVENNPESLIDTCNKLYDSGNEPLQIIIGLLNITRDLLLHTT
HHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECC
NNKYSDLYYTSDEFRDELDKISKTINKSKIVNWHNNLRNIEYQIKSSDNPRLWLEIHLTG
CCCCCCEEECCHHHHHHHHHHHHHHHHHHEEEHHHCCCCEEEEEECCCCCEEEEEEEEEE
LLDSQEINSLENKKESKNNTTEEHESRKNIPINKENISHEIPKPSIQEEITHKELIEKKE
CCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHH
EKLEKFEVLEKESIENISENNQNNPRSNLKDKWELILSKVELPSTRMLLSQQAELESFDS
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
EKITIALSPNWENMIKSRKVIIEDTVKKIFGDGIILNFSTKQLNKSNPTNTPEITQNEVN
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCCCCCCCCCCCCHHHHH
NFRPIKKIEPKTNSTTKISNEETYDDSSKNLANFFNGEIIDLDE
CCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCC
>Mature Secondary Structure 
PNIHKPFHQKYRPNNLDELVGQKFISITLKQALLTKKIAPAYLFNGPRGTGKTSSARIF
CCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCEEE
AKSLNCQAFDQPTITPCCKCDLCRQITEGSALDIIEIDAASNTGVENIREIIERARFAPT
EECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
QARWKVYVIDECHMLSTAASNALLKTIEEPPSRVVFILATTNPERVLNTIKSRCQKFDFR
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
RISPSDIFQHLSEISEKESIKYEVQALKMIAKRSNGGMRDAQSLLEQLNLLPEGITINGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEHHH
QNLLGEVSESELTNLIKSLVENNPESLIDTCNKLYDSGNEPLQIIIGLLNITRDLLLHTT
HHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECC
NNKYSDLYYTSDEFRDELDKISKTINKSKIVNWHNNLRNIEYQIKSSDNPRLWLEIHLTG
CCCCCCEEECCHHHHHHHHHHHHHHHHHHEEEHHHCCCCEEEEEECCCCCEEEEEEEEEE
LLDSQEINSLENKKESKNNTTEEHESRKNIPINKENISHEIPKPSIQEEITHKELIEKKE
CCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHH
EKLEKFEVLEKESIENISENNQNNPRSNLKDKWELILSKVELPSTRMLLSQQAELESFDS
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
EKITIALSPNWENMIKSRKVIIEDTVKKIFGDGIILNFSTKQLNKSNPTNTPEITQNEVN
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCCCCCCCCCCCCHHHHH
NFRPIKKIEPKTNSTTKISNEETYDDSSKNLANFFNGEIIDLDE
CCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]