Click here to switch to the map view.

The map label for this gene is clpX [H]

Identifier: 123969398

GI number: 123969398

Start: 1600265

End: 1601632

Strand: Direct

Name: clpX [H]

Synonym: A9601_18661

Alternate gene names: 123969398

Gene position: 1600265-1601632 (Clockwise)

Preceding gene: 123969397

Following gene: 123969399

Centisome position: 95.83

GC content: 33.41

Gene sequence:

>1368_bases
ATGGCTAAATTCGACGCCCATCTTAAATGTTCATTTTGCGGTAAATCACAAGACCAAGTAAGAAAGCTTATAGCTGGTCC
TGGGGTTTATATCTGTGATGAGTGCATAGATCTTTGTAATGAAATTCTCGATGAAGAACTACTTGATAATCAAGCGAACA
CAAACAACCCTCCGCAAGTAAAAAAGAAATTACCAACTGATAATCCAAAAAAATCTGTTCCTTTAGAATTAACCTCAATT
CCTAAGCCATTAGAAATTAAAAGTTTTCTAGATAATCAAGTTGTTGGACAAGAATCCGCAAAAAAAATATTATCAGTCGC
CGTATACAATCACTACAAGCGATTAGCTTGGAAAGTTAAAGAAGATAGTAAAAATAACAATGCAACAGATTCACAAGCAA
CTAAATTACAAAAATCAAATATTTTACTCATCGGCCCTACTGGAAGTGGAAAAACATTATTGGCGCAAACTTTAGCAGAG
TTTTTAGATGTTCCTTTTGCAGTAGCTGATGCAACGACTTTGACAGAAGCTGGATATGTTGGGGAGGATGTTGAAAACAT
ACTTTTAAGACTTCTACAGAAATCAGAAATGAATGTAGAACTAGCTCAAAAAGGAATTATTTATATTGATGAAATAGATA
AAATTGCAAGAAAAAGCGAGAATCCCTCAATTACTAGAGATGTCTCTGGTGAAGGAGTACAGCAAGCTTTATTAAAAATG
CTTGAAGGAACAATTGCTAATGTGCCACCACAAGGCGGAAGAAAACATCCGTATCATGACTGTATCCAAATTGATACGAG
TCAAATACTATTTATTTGTGGGGGAGCTTTTATAGGTTTAGAGGATATCGTTCAAAAGCGTATGGGTAAACACTCTATAG
GTTTTACCACCAATTCAGATCAAAACAAAGTTGATACAAAAAAAATAGTAGACCCAAGAGATTCCCTGAAAAATTTAGAA
TTAGATGACTTAGTGAAATATGGCCTAATTCCAGAATTTATTGGAAGAATTCCGGTTTGTGCTGTATTAGATCGTCTTAC
TAAAGAAACTTTAGAATCTATTTTGACTCAACCAAGAGATGCATTAGTAAAGCAATTCAAAACTTTGCTAAGTATGGATA
ATGTTGAATTATCATTTGAGCCTGATTCTGTTGAAGCGATAGCAAATGAAGCATACAAAAGAAAAACAGGTGCAAGAGCA
TTAAGATCAATAATTGAAGAGCTAATGCTAGACATAATGTATACTTTGCCTTCTGAAGAAAATGTAAAAGAATTCACAAT
TACGAAAAAAATGGTAGATAATTTGTTCTCATCTAAAATTGTTAAACTACCTTCAGGATCAAAAAGAATCATTAAAGAGT
CTGCATAA

Upstream 100 bases:

>100_bases
GTTCTGATTTTTTAAGAATAAGATGACGAATCGATATTTATAAGCAATCCTAGTGAATAGGGAATATTTAACACCTTTCA
CTTTTAAAAACTTATTATCG

Downstream 100 bases:

>100_bases
AATTATAGTTTAATTTTTTTAATTGAATCCCTAATTTTTCTAATTAATGAAAAATAAATGCCAAATATACATAAACCTTT
TCATCAAAAATATAGACCAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNPPQVKKKLPTDNPKKSVPLELTSI
PKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKVKEDSKNNNATDSQATKLQKSNILLIGPTGSGKTLLAQTLAE
FLDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSDQNKVDTKKIVDPRDSLKNLE
LDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRDALVKQFKTLLSMDNVELSFEPDSVEAIANEAYKRKTGARA
LRSIIEELMLDIMYTLPSEENVKEFTITKKMVDNLFSSKIVKLPSGSKRIIKESA

Sequences:

>Translated_455_residues
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNPPQVKKKLPTDNPKKSVPLELTSI
PKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKVKEDSKNNNATDSQATKLQKSNILLIGPTGSGKTLLAQTLAE
FLDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSDQNKVDTKKIVDPRDSLKNLE
LDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRDALVKQFKTLLSMDNVELSFEPDSVEAIANEAYKRKTGARA
LRSIIEELMLDIMYTLPSEENVKEFTITKKMVDNLFSSKIVKLPSGSKRIIKESA
>Mature_454_residues
AKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNPPQVKKKLPTDNPKKSVPLELTSIP
KPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKVKEDSKNNNATDSQATKLQKSNILLIGPTGSGKTLLAQTLAEF
LDVPFAVADATTLTEAGYVGEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKML
EGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSDQNKVDTKKIVDPRDSLKNLEL
DDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRDALVKQFKTLLSMDNVELSFEPDSVEAIANEAYKRKTGARAL
RSIIEELMLDIMYTLPSEENVKEFTITKKMVDNLFSSKIVKLPSGSKRIIKESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=418, Percent_Identity=41.6267942583732, Blast_Score=290, Evalue=2e-78,
Organism=Escherichia coli, GI1786642, Length=430, Percent_Identity=55.5813953488372, Blast_Score=470, Evalue=1e-134,
Organism=Escherichia coli, GI1790366, Length=217, Percent_Identity=31.3364055299539, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=295, Percent_Identity=45.4237288135593, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=297, Percent_Identity=45.7912457912458, Blast_Score=268, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=451, Percent_Identity=37.4722838137472, Blast_Score=254, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=291, Percent_Identity=38.4879725085911, Blast_Score=169, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=431, Percent_Identity=37.122969837587, Blast_Score=246, Evalue=7e-66,
Organism=Drosophila melanogaster, GI24648291, Length=317, Percent_Identity=46.3722397476341, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI24648289, Length=317, Percent_Identity=46.3722397476341, Blast_Score=284, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 50532; Mature: 50401

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNPPQV
CCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
KKKLPTDNPKKSVPLELTSIPKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKVK
HHCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EDSKNNNATDSQATKLQKSNILLIGPTGSGKTLLAQTLAEFLDVPFAVADATTLTEAGYV
CCCCCCCCCCHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCC
GEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
CHHHHHHHHHHHHHHCCCHHHHHCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSD
HHHHHCCCCCCCCCCCCCHHHHEECCHHEEEECCCHHCCHHHHHHHHHCCCCCCCCCCCC
QNKVDTKKIVDPRDSLKNLELDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRD
CCCCCHHHHCCCHHHHCCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHH
ALVKQFKTLLSMDNVELSFEPDSVEAIANEAYKRKTGARALRSIIEELMLDIMYTLPSEE
HHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NVKEFTITKKMVDNLFSSKIVKLPSGSKRIIKESA
CHHHHHHHHHHHHHHHHHCEEECCCCCHHHHCCCC
>Mature Secondary Structure 
AKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELLDNQANTNNPPQV
CCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
KKKLPTDNPKKSVPLELTSIPKPLEIKSFLDNQVVGQESAKKILSVAVYNHYKRLAWKVK
HHCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EDSKNNNATDSQATKLQKSNILLIGPTGSGKTLLAQTLAEFLDVPFAVADATTLTEAGYV
CCCCCCCCCCHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCC
GEDVENILLRLLQKSEMNVELAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKM
CHHHHHHHHHHHHHHCCCHHHHHCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LEGTIANVPPQGGRKHPYHDCIQIDTSQILFICGGAFIGLEDIVQKRMGKHSIGFTTNSD
HHHHHCCCCCCCCCCCCCHHHHEECCHHEEEECCCHHCCHHHHHHHHHCCCCCCCCCCCC
QNKVDTKKIVDPRDSLKNLELDDLVKYGLIPEFIGRIPVCAVLDRLTKETLESILTQPRD
CCCCCHHHHCCCHHHHCCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHH
ALVKQFKTLLSMDNVELSFEPDSVEAIANEAYKRKTGARALRSIIEELMLDIMYTLPSEE
HHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NVKEFTITKKMVDNLFSSKIVKLPSGSKRIIKESA
CHHHHHHHHHHHHHHHHHCEEECCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA