Click here to switch to the map view.

The map label for this gene is ribH [H]

Identifier: 123969384

GI number: 123969384

Start: 1582833

End: 1583309

Strand: Reverse

Name: ribH [H]

Synonym: A9601_18521

Alternate gene names: 123969384

Gene position: 1583309-1582833 (Counterclockwise)

Preceding gene: 123969385

Following gene: 123969383

Centisome position: 94.82

GC content: 32.91

Gene sequence:

>477_bases
ATGGCTATTTTTGAGGGTTCTTTTACTACGGCCTCTACTTTAAAAGTTGGGATTGTAATAGCAAGATTTAACGATTTAAT
TACAAATAAAATTCTATCTGGTTGTCTTGATTGTTTAAAAAGACATGGTTTAGATACTTCTGAATTAAGCAATCAAGTAG
ATATAGTTTGGGTTCCAGGTTCATTTGAATTACCAATCGCAGCTAAAACCCTCATGAAAAAAAAGAGTTATGACGTTGTA
ATTGCTCTTGGGGCTGTGATCCGTGGTGAAACTTCCCACTATGATGTAGTTATATCTGAGGCGAGCAAAGGTATTTCGCA
AGTTTCAAATGAAAATAATGTTCCAATTATTTTTGGAGTTTTAACTACTGATACTATGCAGCAGGCTTTAGAAAGAGCAG
GGATTAAGAATAATCTTGGTTGGAATTATGCTTTACAAGCAATTGAGATGGGATCTTTAATTAAAAATTTAAATTAA

Upstream 100 bases:

>100_bases
GTTTGGGTTGTTTTGGTTTTTGTTACAGGGATAGTTTCTTCATTAGTTTGAACTTAATACCTTTTCGTGAGAGTCTATTA
ATATATCTAAGTAAAATTTA

Downstream 100 bases:

>100_bases
TTGAAAAAAATTTAATTATTTTTATCATTGATCCCTTCTTTGAGATAAAATAAAAAAGTTATGCGGATGTAGCTCAGTGG
TAGAGCATCTCCTTGCCAAG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MAIFEGSFTTASTLKVGIVIARFNDLITNKILSGCLDCLKRHGLDTSELSNQVDIVWVPGSFELPIAAKTLMKKKSYDVV
IALGAVIRGETSHYDVVISEASKGISQVSNENNVPIIFGVLTTDTMQQALERAGIKNNLGWNYALQAIEMGSLIKNLN

Sequences:

>Translated_158_residues
MAIFEGSFTTASTLKVGIVIARFNDLITNKILSGCLDCLKRHGLDTSELSNQVDIVWVPGSFELPIAAKTLMKKKSYDVV
IALGAVIRGETSHYDVVISEASKGISQVSNENNVPIIFGVLTTDTMQQALERAGIKNNLGWNYALQAIEMGSLIKNLN
>Mature_157_residues
AIFEGSFTTASTLKVGIVIARFNDLITNKILSGCLDCLKRHGLDTSELSNQVDIVWVPGSFELPIAAKTLMKKKSYDVVI
ALGAVIRGETSHYDVVISEASKGISQVSNENNVPIIFGVLTTDTMQQALERAGIKNNLGWNYALQAIEMGSLIKNLN

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=156, Percent_Identity=46.1538461538462, Blast_Score=139, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6324429, Length=150, Percent_Identity=32.6666666666667, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 17144; Mature: 17013

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIFEGSFTTASTLKVGIVIARFNDLITNKILSGCLDCLKRHGLDTSELSNQVDIVWVPG
CEEECCCCCCHHHHHEHHHEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEECC
SFELPIAAKTLMKKKSYDVVIALGAVIRGETSHYDVVISEASKGISQVSNENNVPIIFGV
CCCCCHHHHHHHHCCCCCEEEEECHHHCCCCCCEEEEEEHHHHHHHHHCCCCCCCEEEEE
LTTDTMQQALERAGIKNNLGWNYALQAIEMGSLIKNLN
ECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIFEGSFTTASTLKVGIVIARFNDLITNKILSGCLDCLKRHGLDTSELSNQVDIVWVPG
EEECCCCCCHHHHHEHHHEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEECC
SFELPIAAKTLMKKKSYDVVIALGAVIRGETSHYDVVISEASKGISQVSNENNVPIIFGV
CCCCCHHHHHHHHCCCCCEEEEECHHHCCCCCCEEEEEEHHHHHHHHHCCCCCCCEEEEE
LTTDTMQQALERAGIKNNLGWNYALQAIEMGSLIKNLN
ECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA