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The map label for this gene is wzb [C]

Identifier: 123969332

GI number: 123969332

Start: 1533288

End: 1533761

Strand: Reverse

Name: wzb [C]

Synonym: A9601_18001

Alternate gene names: 123969332

Gene position: 1533761-1533288 (Counterclockwise)

Preceding gene: 123969333

Following gene: 123969330

Centisome position: 91.85

GC content: 33.76

Gene sequence:

>474_bases
ATGAATAAAATTTCTGTTCTTTTTGTATGTTTGGGAAATATTTGTAGGTCTCCTGCAGCAGAAGCTATCTTTATAAGTCT
ACTTGAAAACAAAGGACTAACCGATGGCTTTATTGTAGATTCTGCTGGAACTGGGAGTTGGCATATTGGAAAAAAAGCTG
ACTCAAGGATGAGAATTGCGGCAGAAAGAAGAGATATACATATCTTAAGCAGAGCTCGTCAAATTACTAGCAAAGATTTT
GGCGAATTTAACTATATTCTTGCGATGGACGATTCAAATTTTAGAAATATTCAAGATCTTAAAAATAGAACAGCTTCAAC
TGGTTTTGCATCAATTAAAAAAATACAAAATTTTAGATCAGTTTTTAATGAGCAAGAAGTTCCTGACCCATATTTTGGAG
GTGATGAGGGCTTCGATTATGTCCTTGATATTTTAGAAGACTCTGTAAGCGGTTTTTTGGAAAGTATTTCTTGA

Upstream 100 bases:

>100_bases
TGTTGTCGAGTTTGTTTGGTCAAGAATTTACTGAATCTTTAATTGAAGAAGTTTTATTTACTACTTAAAAGTCTTATAAT
TTATTGGAATTTGAAATCAT

Downstream 100 bases:

>100_bases
ATTTATTTGATCTCACTCTCTTTAGGAATCTTGTCATTATAAAGATCGATAATTTTATCCACTACCTCATTAATTGAATA
TCCATCCGTAATAATTTCTA

Product: low molecular weight phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MNKISVLFVCLGNICRSPAAEAIFISLLENKGLTDGFIVDSAGTGSWHIGKKADSRMRIAAERRDIHILSRARQITSKDF
GEFNYILAMDDSNFRNIQDLKNRTASTGFASIKKIQNFRSVFNEQEVPDPYFGGDEGFDYVLDILEDSVSGFLESIS

Sequences:

>Translated_157_residues
MNKISVLFVCLGNICRSPAAEAIFISLLENKGLTDGFIVDSAGTGSWHIGKKADSRMRIAAERRDIHILSRARQITSKDF
GEFNYILAMDDSNFRNIQDLKNRTASTGFASIKKIQNFRSVFNEQEVPDPYFGGDEGFDYVLDILEDSVSGFLESIS
>Mature_157_residues
MNKISVLFVCLGNICRSPAAEAIFISLLENKGLTDGFIVDSAGTGSWHIGKKADSRMRIAAERRDIHILSRARQITSKDF
GEFNYILAMDDSNFRNIQDLKNRTASTGFASIKKIQNFRSVFNEQEVPDPYFGGDEGFDYVLDILEDSVSGFLESIS

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=152, Percent_Identity=38.1578947368421, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI4757714, Length=152, Percent_Identity=40.1315789473684, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI96304457, Length=76, Percent_Identity=46.0526315789474, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325330, Length=139, Percent_Identity=35.2517985611511, Blast_Score=92, Evalue=3e-20,
Organism=Drosophila melanogaster, GI78706766, Length=152, Percent_Identity=32.8947368421053, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI78706768, Length=152, Percent_Identity=32.8947368421053, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI78711846, Length=156, Percent_Identity=39.1025641025641, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI78706770, Length=155, Percent_Identity=34.1935483870968, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI78706772, Length=155, Percent_Identity=34.1935483870968, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI78706764, Length=128, Percent_Identity=35.15625, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17525; Mature: 17525

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKISVLFVCLGNICRSPAAEAIFISLLENKGLTDGFIVDSAGTGSWHIGKKADSRMRIA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCEECCCCCCCHHHHH
AERRDIHILSRARQITSKDFGEFNYILAMDDSNFRNIQDLKNRTASTGFASIKKIQNFRS
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
VFNEQEVPDPYFGGDEGFDYVLDILEDSVSGFLESIS
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKISVLFVCLGNICRSPAAEAIFISLLENKGLTDGFIVDSAGTGSWHIGKKADSRMRIA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCEECCCCCCCHHHHH
AERRDIHILSRARQITSKDFGEFNYILAMDDSNFRNIQDLKNRTASTGFASIKKIQNFRS
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
VFNEQEVPDPYFGGDEGFDYVLDILEDSVSGFLESIS
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]