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The map label for this gene is bioD [H]

Identifier: 123969205

GI number: 123969205

Start: 1416045

End: 1416710

Strand: Direct

Name: bioD [H]

Synonym: A9601_16731

Alternate gene names: 123969205

Gene position: 1416045-1416710 (Clockwise)

Preceding gene: 123969204

Following gene: 123969206

Centisome position: 84.8

GC content: 30.93

Gene sequence:

>666_bases
ATGAGTAGTCACAAAAATATTTTCAAATTTATAATTTGTGGAACAGATACTGATATTGGGAAAACTTTAATAAGCTCTTT
TTTCGTTAAAGGATTAAATTCCTTTTATTGGAAACCTATTCAAAGTGGGATTGAATCACAAACTGATAGTCAAACTGTTG
AAAAACTTGCACAAGTAAGTAAAGAGAAAATAATCAAAGAAGCTTATGTCTTTACAAAACCTCTATCTCCTCATTGGGCT
GCTGAAATAGATCAAAAAGCTATTAACTTTGACAAGTTGAGATTACCAAAAGTGCGAGGCTCATTAATTATAGAAACTGC
AGGTGGATTAATGGTTCCAATAACACGCAATTTTTTGCAAATAGATCAAATAAAAGAATGGAATCTTCCGGTAATACTTG
TATGTAAGAGCGCACTTGGCACTCTTAACCATACCCTGCTTAGTATTGAGGCCTTAAAACGAAGAAATATTGAGATTTTA
GGTTTAGTAGTCAATGGCGAAAAACACCTAGATAATCCAAAAACTCTAGTTGATTTTAGTGGTATTCCTTTAATTGCTGA
ATTTCCTTACATCAAAAAAATGGACTCAAATAATTTAGATATACTATGGAAAGAACTAGACATCAAAAATAAGTTGATCT
CACTATTAAACTCAAAAATAAGTTAA

Upstream 100 bases:

>100_bases
CAGTGAGAGAGTTAAAGGAAATTCAAAAGTTTTGGCCAAAGAATTACAATAATACAGTAAACCTTTCATGGGAAATTGAG
ATTCAAATCATAAAGAAATT

Downstream 100 bases:

>100_bases
ATGAAATCTTTGGATTCAAAAACTCCAAATCAAGATTGGCACCCAAATATTTGGCCACCTTTTACGCAAATCAATAACAG
CAAACCTCAGATTGAAGTAA

Product: putative dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSSHKNIFKFIICGTDTDIGKTLISSFFVKGLNSFYWKPIQSGIESQTDSQTVEKLAQVSKEKIIKEAYVFTKPLSPHWA
AEIDQKAINFDKLRLPKVRGSLIIETAGGLMVPITRNFLQIDQIKEWNLPVILVCKSALGTLNHTLLSIEALKRRNIEIL
GLVVNGEKHLDNPKTLVDFSGIPLIAEFPYIKKMDSNNLDILWKELDIKNKLISLLNSKIS

Sequences:

>Translated_221_residues
MSSHKNIFKFIICGTDTDIGKTLISSFFVKGLNSFYWKPIQSGIESQTDSQTVEKLAQVSKEKIIKEAYVFTKPLSPHWA
AEIDQKAINFDKLRLPKVRGSLIIETAGGLMVPITRNFLQIDQIKEWNLPVILVCKSALGTLNHTLLSIEALKRRNIEIL
GLVVNGEKHLDNPKTLVDFSGIPLIAEFPYIKKMDSNNLDILWKELDIKNKLISLLNSKIS
>Mature_220_residues
SSHKNIFKFIICGTDTDIGKTLISSFFVKGLNSFYWKPIQSGIESQTDSQTVEKLAQVSKEKIIKEAYVFTKPLSPHWAA
EIDQKAINFDKLRLPKVRGSLIIETAGGLMVPITRNFLQIDQIKEWNLPVILVCKSALGTLNHTLLSIEALKRRNIEILG
LVVNGEKHLDNPKTLVDFSGIPLIAEFPYIKKMDSNNLDILWKELDIKNKLISLLNSKIS

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=210, Percent_Identity=26.1904761904762, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324385, Length=207, Percent_Identity=33.8164251207729, Blast_Score=105, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24948; Mature: 24816

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHKNIFKFIICGTDTDIGKTLISSFFVKGLNSFYWKPIQSGIESQTDSQTVEKLAQVS
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KEKIIKEAYVFTKPLSPHWAAEIDQKAINFDKLRLPKVRGSLIIETAGGLMVPITRNFLQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEECCCCCCCEEEEECCCEEEECHHHHHH
IDQIKEWNLPVILVCKSALGTLNHTLLSIEALKRRNIEILGLVVNGEKHLDNPKTLVDFS
HHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECHHHCCCCCEEEECC
GIPLIAEFPYIKKMDSNNLDILWKELDIKNKLISLLNSKIS
CCCEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSHKNIFKFIICGTDTDIGKTLISSFFVKGLNSFYWKPIQSGIESQTDSQTVEKLAQVS
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KEKIIKEAYVFTKPLSPHWAAEIDQKAINFDKLRLPKVRGSLIIETAGGLMVPITRNFLQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEECCCCCCCEEEEECCCEEEECHHHHHH
IDQIKEWNLPVILVCKSALGTLNHTLLSIEALKRRNIEILGLVVNGEKHLDNPKTLVDFS
HHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECHHHCCCCCEEEECC
GIPLIAEFPYIKKMDSNNLDILWKELDIKNKLISLLNSKIS
CCCEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA