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The map label for this gene is nblS [H]

Identifier: 123969074

GI number: 123969074

Start: 1321440

End: 1323506

Strand: Direct

Name: nblS [H]

Synonym: A9601_15421

Alternate gene names: 123969074

Gene position: 1321440-1323506 (Clockwise)

Preceding gene: 123969073

Following gene: 123969077

Centisome position: 79.13

GC content: 35.85

Gene sequence:

>2067_bases
ATGGTGGGTTCCAATAATCAAGAAAGTGCGAAATATAGCATCAATGATAATGAAGAAATGAATAAAAACCATTGGATTAA
TGGACTCCTCGCTTGGTGGAGTGGGTTCAGTTTAAGGACAAAGTTGTTAGCGATAGCAACTCTTGTCGTAAGCCTCCTAA
TGACAGGAATAACTTTCTTTGCATTAAACAGTATCCAAAGAGATGCAGGAATGAACGATACAAGATATGCTCGAGATCTT
GGCTTATTGTTATCTGGGAATGTTACAGAATTAGTCGCTAACAACCAAAAAAAAGAAATTTCAAATGTAGCTGAAAAGTT
TTGGAGATCCAGTCGAAACTTACGTTATATATTCTTTACTGATGCTGAAGATATTGTTCAACTTGGAATACCGATCAGTG
CAACGCCGACAAGCTCAGACAGTCAGTTTCAACTCACTCGAAGACTCAAACTACCCTCTGAATTAAAGAAAAGACCACAA
TTCCCATTGGTTAGACAGCATGCGACCCCTCAAGGTCAAGTAACAGATGTATTTGTCCCAATGTTGTGGAAAGGCAAATA
TCTCGGAACTTTAGCTTTGGGAGTCACCCCGAATAAAAAAGCATTAGCCAGTGCCGCCTTAACTAGAGAAGTAACTATTG
CAGTTTTTATCTCTATTTGGGTTTTAGTAATACTTGGAGCTGTATTTAATGCACTAACTATTACAAGACCCGTCAGAGAG
TTAGTAAGAGGTGTTAGAGAAATTTCAAGAGGAAATTTTAAATCCAGAATTTCTTTACCCATGACAGGTGATCTGGGAGA
ACTCTTAAATGGATTTAACAGAATGGCCACCCAGTTAGAAAATTATGATGAGGCTAATATAGAAGAGCTAAAAGCGGCGC
AAATCAAGCAGCAATCCCTGATAGCTACAATGGCTGATGGTGCCATATTATTGGATTCAAAAGGGAAGATTGTACTCACT
AATCCAACCGCAAAGAGATTATTTCGTTGGGAAGGGAGATTCTTAGAGGGTAAACATTTTTTAAATGAAATCCCCGAAAT
TCTATCTAACGACTTACATTCAAATATTGAATCTATTTTAAACAGGGAAAAGGAGAAAGACGATTTAAGATTCAGTTTAG
GAGAACCAGCAAGAACCCTAAGAATTGTCTTGCAATCAGTTTTGGATACAAATAAAATTGAATTAAAAGGAATAGCCGTA
ACAATCCAAGACTTAACTAGAGAAGTTGAACTTAACGCGGCACAAAATAGATTTATTAGTAATGTTTCGCACGAATTAAG
GACACCTCTTTTTAATATCAAAAGTTATGTAGAGACCTTACATGATTTAAAAGATCAACTTTCTGATGAAGAACAAATAG
AATTTTTGGGAATTGCAAATTCAGAGACTGATAGGTTAACAAGACTTGTAAATGATGTATTAGATTTATCAAGATTAGAG
TCTGGTAAAATTGTTCAACTAGAACAAATGGACATAAAGCCCGCAATAGAGCAGACACTTAGAAACTATAGACTTAATGC
AACAGAAAAAAACGTTTCTTTAGCTCATGATATAGAGGAAACTATTCCTCCAATTCTTGGAAATTTTGATTTACTTTTAC
AGGTTTTTGATAATTTGCTGGGTAATGGATTGAAATTTAGTCCAAAAAACAGCACCCTAATTATAAGAGCTTATACTTGG
CCAGATTCCTGCCCTGCTTTCCCTCCAAGTATTAAAAATGATGCAGCCCCTCAATGTGAATTGGTATCACCACTACCAAA
AGTAAGAATTGAGATTGCTGATACTGGCTCAGGAATATCTCAAGCTGATCAAGAAAAGATCTTTGATCGTTTTTATAGAG
TAGAGAATTCTGTTCATACTGAGCAAGGTACCGGTTTAGGTTTGTCAATCGTGCGAGGAATAATTGAAAAACATGGTGGA
GAAATTCGTATGGCTAGTGAATTAGGAGTAGGAACAACTTTCTGGTTTGATTTAGCTTTAGCACAATCTGATAAAGATGA
ATTATTGACAAAAGCTATTAACAATTCAGATTCTTTCTCCGCTTCTGAAATTAAGGAAATTATCTAA

Upstream 100 bases:

>100_bases
GCATACAAGAATTTAAAAAAAATCCATTTTAAGGGAATTTACTTCAGAAATGACATAGGTTATCAAGTCAGAAAAAACTT
TTCAAAGGAGAATTAAGATT

Downstream 100 bases:

>100_bases
TTATTATCTAATCCTTTAAAAACATTTTGAACATTTTGATCAGGTACAATTCTGTGAGGGGCGCCGCTAAATATTTGTTC
AAAATTAGAAAAAGAATCTC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 688

Protein sequence:

>688_residues
MVGSNNQESAKYSINDNEEMNKNHWINGLLAWWSGFSLRTKLLAIATLVVSLLMTGITFFALNSIQRDAGMNDTRYARDL
GLLLSGNVTELVANNQKKEISNVAEKFWRSSRNLRYIFFTDAEDIVQLGIPISATPTSSDSQFQLTRRLKLPSELKKRPQ
FPLVRQHATPQGQVTDVFVPMLWKGKYLGTLALGVTPNKKALASAALTREVTIAVFISIWVLVILGAVFNALTITRPVRE
LVRGVREISRGNFKSRISLPMTGDLGELLNGFNRMATQLENYDEANIEELKAAQIKQQSLIATMADGAILLDSKGKIVLT
NPTAKRLFRWEGRFLEGKHFLNEIPEILSNDLHSNIESILNREKEKDDLRFSLGEPARTLRIVLQSVLDTNKIELKGIAV
TIQDLTREVELNAAQNRFISNVSHELRTPLFNIKSYVETLHDLKDQLSDEEQIEFLGIANSETDRLTRLVNDVLDLSRLE
SGKIVQLEQMDIKPAIEQTLRNYRLNATEKNVSLAHDIEETIPPILGNFDLLLQVFDNLLGNGLKFSPKNSTLIIRAYTW
PDSCPAFPPSIKNDAAPQCELVSPLPKVRIEIADTGSGISQADQEKIFDRFYRVENSVHTEQGTGLGLSIVRGIIEKHGG
EIRMASELGVGTTFWFDLALAQSDKDELLTKAINNSDSFSASEIKEII

Sequences:

>Translated_688_residues
MVGSNNQESAKYSINDNEEMNKNHWINGLLAWWSGFSLRTKLLAIATLVVSLLMTGITFFALNSIQRDAGMNDTRYARDL
GLLLSGNVTELVANNQKKEISNVAEKFWRSSRNLRYIFFTDAEDIVQLGIPISATPTSSDSQFQLTRRLKLPSELKKRPQ
FPLVRQHATPQGQVTDVFVPMLWKGKYLGTLALGVTPNKKALASAALTREVTIAVFISIWVLVILGAVFNALTITRPVRE
LVRGVREISRGNFKSRISLPMTGDLGELLNGFNRMATQLENYDEANIEELKAAQIKQQSLIATMADGAILLDSKGKIVLT
NPTAKRLFRWEGRFLEGKHFLNEIPEILSNDLHSNIESILNREKEKDDLRFSLGEPARTLRIVLQSVLDTNKIELKGIAV
TIQDLTREVELNAAQNRFISNVSHELRTPLFNIKSYVETLHDLKDQLSDEEQIEFLGIANSETDRLTRLVNDVLDLSRLE
SGKIVQLEQMDIKPAIEQTLRNYRLNATEKNVSLAHDIEETIPPILGNFDLLLQVFDNLLGNGLKFSPKNSTLIIRAYTW
PDSCPAFPPSIKNDAAPQCELVSPLPKVRIEIADTGSGISQADQEKIFDRFYRVENSVHTEQGTGLGLSIVRGIIEKHGG
EIRMASELGVGTTFWFDLALAQSDKDELLTKAINNSDSFSASEIKEII
>Mature_688_residues
MVGSNNQESAKYSINDNEEMNKNHWINGLLAWWSGFSLRTKLLAIATLVVSLLMTGITFFALNSIQRDAGMNDTRYARDL
GLLLSGNVTELVANNQKKEISNVAEKFWRSSRNLRYIFFTDAEDIVQLGIPISATPTSSDSQFQLTRRLKLPSELKKRPQ
FPLVRQHATPQGQVTDVFVPMLWKGKYLGTLALGVTPNKKALASAALTREVTIAVFISIWVLVILGAVFNALTITRPVRE
LVRGVREISRGNFKSRISLPMTGDLGELLNGFNRMATQLENYDEANIEELKAAQIKQQSLIATMADGAILLDSKGKIVLT
NPTAKRLFRWEGRFLEGKHFLNEIPEILSNDLHSNIESILNREKEKDDLRFSLGEPARTLRIVLQSVLDTNKIELKGIAV
TIQDLTREVELNAAQNRFISNVSHELRTPLFNIKSYVETLHDLKDQLSDEEQIEFLGIANSETDRLTRLVNDVLDLSRLE
SGKIVQLEQMDIKPAIEQTLRNYRLNATEKNVSLAHDIEETIPPILGNFDLLLQVFDNLLGNGLKFSPKNSTLIIRAYTW
PDSCPAFPPSIKNDAAPQCELVSPLPKVRIEIADTGSGISQADQEKIFDRFYRVENSVHTEQGTGLGLSIVRGIIEKHGG
EIRMASELGVGTTFWFDLALAQSDKDELLTKAINNSDSFSASEIKEII

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc; May Activate Atoc By Phosphorylation. [C]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=411, Percent_Identity=26.0340632603406, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=28.1746031746032, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1789149, Length=268, Percent_Identity=28.3582089552239, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788393, Length=285, Percent_Identity=28.4210526315789, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI87082128, Length=313, Percent_Identity=26.1980830670927, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1786600, Length=415, Percent_Identity=24.3373493975904, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693157, Length=265, Percent_Identity=28.3018867924528, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=272, Percent_Identity=24.6323529411765, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=28.2868525896414, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1788279, Length=225, Percent_Identity=26.2222222222222, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=264, Percent_Identity=23.4848484848485, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790300, Length=359, Percent_Identity=24.7910863509749, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=25.9109311740891, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77026; Mature: 77026

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGSNNQESAKYSINDNEEMNKNHWINGLLAWWSGFSLRTKLLAIATLVVSLLMTGITFF
CCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALNSIQRDAGMNDTRYARDLGLLLSGNVTELVANNQKKEISNVAEKFWRSSRNLRYIFFT
HHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEE
DAEDIVQLGIPISATPTSSDSQFQLTRRLKLPSELKKRPQFPLVRQHATPQGQVTDVFVP
CHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCCHHCCCCCCCCCHHHHHH
MLWKGKYLGTLALGVTPNKKALASAALTREVTIAVFISIWVLVILGAVFNALTITRPVRE
HHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVRGVREISRGNFKSRISLPMTGDLGELLNGFNRMATQLENYDEANIEELKAAQIKQQSL
HHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IATMADGAILLDSKGKIVLTNPTAKRLFRWEGRFLEGKHFLNEIPEILSNDLHSNIESIL
HHHHCCCEEEEECCCCEEEECCHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
NREKEKDDLRFSLGEPARTLRIVLQSVLDTNKIELKGIAVTIQDLTREVELNAAQNRFIS
HCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHH
NVSHELRTPLFNIKSYVETLHDLKDQLSDEEQIEFLGIANSETDRLTRLVNDVLDLSRLE
HHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHCC
SGKIVQLEQMDIKPAIEQTLRNYRLNATEKNVSLAHDIEETIPPILGNFDLLLQVFDNLL
CCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHHH
GNGLKFSPKNSTLIIRAYTWPDSCPAFPPSIKNDAAPQCELVSPLPKVRIEIADTGSGIS
CCCCEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEEEECCCCCCC
QADQEKIFDRFYRVENSVHTEQGTGLGLSIVRGIIEKHGGEIRMASELGVGTTFWFDLAL
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHH
AQSDKDELLTKAINNSDSFSASEIKEII
HCCCHHHHHHHHHCCCCCCCHHHHHHHC
>Mature Secondary Structure
MVGSNNQESAKYSINDNEEMNKNHWINGLLAWWSGFSLRTKLLAIATLVVSLLMTGITFF
CCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALNSIQRDAGMNDTRYARDLGLLLSGNVTELVANNQKKEISNVAEKFWRSSRNLRYIFFT
HHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEE
DAEDIVQLGIPISATPTSSDSQFQLTRRLKLPSELKKRPQFPLVRQHATPQGQVTDVFVP
CHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCCHHCCCCCCCCCHHHHHH
MLWKGKYLGTLALGVTPNKKALASAALTREVTIAVFISIWVLVILGAVFNALTITRPVRE
HHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVRGVREISRGNFKSRISLPMTGDLGELLNGFNRMATQLENYDEANIEELKAAQIKQQSL
HHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IATMADGAILLDSKGKIVLTNPTAKRLFRWEGRFLEGKHFLNEIPEILSNDLHSNIESIL
HHHHCCCEEEEECCCCEEEECCHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
NREKEKDDLRFSLGEPARTLRIVLQSVLDTNKIELKGIAVTIQDLTREVELNAAQNRFIS
HCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHH
NVSHELRTPLFNIKSYVETLHDLKDQLSDEEQIEFLGIANSETDRLTRLVNDVLDLSRLE
HHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHCC
SGKIVQLEQMDIKPAIEQTLRNYRLNATEKNVSLAHDIEETIPPILGNFDLLLQVFDNLL
CCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHHH
GNGLKFSPKNSTLIIRAYTWPDSCPAFPPSIKNDAAPQCELVSPLPKVRIEIADTGSGIS
CCCCEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEEEECCCCCCC
QADQEKIFDRFYRVENSVHTEQGTGLGLSIVRGIIEKHGGEIRMASELGVGTTFWFDLAL
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHH
AQSDKDELLTKAINNSDSFSASEIKEII
HCCCHHHHHHHHHCCCCCCCHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8535519; 8905231; 3141423 [H]