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The map label for this gene is murA [H]

Identifier: 123969031

GI number: 123969031

Start: 1280649

End: 1282019

Strand: Direct

Name: murA [H]

Synonym: A9601_14991

Alternate gene names: 123969031

Gene position: 1280649-1282019 (Clockwise)

Preceding gene: 123969026

Following gene: 123969032

Centisome position: 76.69

GC content: 33.77

Gene sequence:

>1371_bases
ATGATTTGCGGAAGCAAAACGAAGTCATATCTTAAATCGCAAAATTTAAAGATTCTTGGCCAAGGCAAGTTAAATGGAAT
AGTTGAAATAAGTGGTGCTAAGAATTCCGCCTTAGTTTTATTAGCCTCATCATTGCTAACTAATGAAAAAATAATTCTTG
AAAATGTACCTTTTCTCACTGATATTGAAAAGATGGGGAATATCCTAAAGAATCTAGGAGTGAATTTAGTTCGTAAAAAC
AACCAACTAGAAATAGATCCAACAACTATTTCGATTAAAGAACTTCCATATGAACTTGTTAAAGGATTAAGAGCTAGTTT
CTTTTGTATAGGTGCACTATTAACTAAATTTGGAGAAGCTCAAGTACCGTTACCAGGTGGATGCAACATTGGTTCAAGGC
CAATAGAAGAGCACATTAATGGATTAATCGCACTAGGAGCAGAAATTATTATTGAAAAGGGAATTGTAAAGGCAAAAATA
AGGGGGAACAAAAATAGACTTCATGGCACTCATATTAAATTAAATTGTCCAAGTGTAGGTGCGACTGAAACTTTAATTAT
GGCAGCATCTTTAGCCAAAGGAAGAACTACTATTGAAAATGCTGCTAGAGAGCCTGAAGTTCAAGATTTATGCCAAATGC
TTAATAAAATGGGGGCAAAAATTTATGACTCCGGTAAAGAAACAATCATTATTGATGGTGTTAATAAGCTTGGCGGATGT
ACCCATAAAGTAATTCCAGACCGAATAGAAGCTGGGACTTTTCTAATTGCTGCTGCTGCAACTTCCTCTTCAATAACAAT
TTCTCCAGTAATCCCTCATCATCTTGAAGCTGTCACTAATAAGCTTCAAGAGAGTGGGAGTAAAATTACGATTAAAGGTA
ATTCTATTTCTATCAAGAGTAAAGAGATTAAAGGAGTAGATATTGAAACAGCTCCTTTCCCAGGCTTTCCTACTGATTTG
CAGGCACCATTTACAACTCTAATGACAATCGCAAATGGTGAATCAAAGATAACTGAAACAATTTTCGAAAACAGAATGAA
TCATATTTATCTACTTAATGAAATGGGCGCCAGTATAAAACTAAACAAAAACGTAGCTCACATCAAAGGTGTTAAAACAA
TTAATGGGATGAATCTAGTTGGCTCAGATTTAAGGTCATCAGCTGCATTAATAATTGCAGGAATCATCGCAAAAGGTAGT
AGTAATTTCTATGGATTAGAACATCTTGATAGAGGTTATGAAAATTTTGAATTAAAACTAAAAAATTTAGGTGTAAAAAT
AATTAGAGAGATCAGTAAAAATACTTTTGAGGAGAATGGATATAAAATTGAATCTAAATCTGAGAATCTTTCAAAACTCG
GAGCAGCCTAA

Upstream 100 bases:

>100_bases
CAAAAAATACATTTTCACTTTTAATTAATATTCATGACGTTACATAGGGTGGACTTAATAATATTAGTTTGTCATGATGA
ATCTAATAAATTAAGTCTTA

Downstream 100 bases:

>100_bases
CCTTTTCCAAATATGTTTTTAAAACTAAGGGAATTGATTTAAACGTAAGCAATATTAATTAGTGAAATACAACCCAAAAA
TAATATAAACAAAACTAGAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MICGSKTKSYLKSQNLKILGQGKLNGIVEISGAKNSALVLLASSLLTNEKIILENVPFLTDIEKMGNILKNLGVNLVRKN
NQLEIDPTTISIKELPYELVKGLRASFFCIGALLTKFGEAQVPLPGGCNIGSRPIEEHINGLIALGAEIIIEKGIVKAKI
RGNKNRLHGTHIKLNCPSVGATETLIMAASLAKGRTTIENAAREPEVQDLCQMLNKMGAKIYDSGKETIIIDGVNKLGGC
THKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKSKEIKGVDIETAPFPGFPTDL
QAPFTTLMTIANGESKITETIFENRMNHIYLLNEMGASIKLNKNVAHIKGVKTINGMNLVGSDLRSSAALIIAGIIAKGS
SNFYGLEHLDRGYENFELKLKNLGVKIIREISKNTFEENGYKIESKSENLSKLGAA

Sequences:

>Translated_456_residues
MICGSKTKSYLKSQNLKILGQGKLNGIVEISGAKNSALVLLASSLLTNEKIILENVPFLTDIEKMGNILKNLGVNLVRKN
NQLEIDPTTISIKELPYELVKGLRASFFCIGALLTKFGEAQVPLPGGCNIGSRPIEEHINGLIALGAEIIIEKGIVKAKI
RGNKNRLHGTHIKLNCPSVGATETLIMAASLAKGRTTIENAAREPEVQDLCQMLNKMGAKIYDSGKETIIIDGVNKLGGC
THKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKSKEIKGVDIETAPFPGFPTDL
QAPFTTLMTIANGESKITETIFENRMNHIYLLNEMGASIKLNKNVAHIKGVKTINGMNLVGSDLRSSAALIIAGIIAKGS
SNFYGLEHLDRGYENFELKLKNLGVKIIREISKNTFEENGYKIESKSENLSKLGAA
>Mature_456_residues
MICGSKTKSYLKSQNLKILGQGKLNGIVEISGAKNSALVLLASSLLTNEKIILENVPFLTDIEKMGNILKNLGVNLVRKN
NQLEIDPTTISIKELPYELVKGLRASFFCIGALLTKFGEAQVPLPGGCNIGSRPIEEHINGLIALGAEIIIEKGIVKAKI
RGNKNRLHGTHIKLNCPSVGATETLIMAASLAKGRTTIENAAREPEVQDLCQMLNKMGAKIYDSGKETIIIDGVNKLGGC
THKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKSKEIKGVDIETAPFPGFPTDL
QAPFTTLMTIANGESKITETIFENRMNHIYLLNEMGASIKLNKNVAHIKGVKTINGMNLVGSDLRSSAALIIAGIIAKGS
SNFYGLEHLDRGYENFELKLKNLGVKIIREISKNTFEENGYKIESKSENLSKLGAA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=416, Percent_Identity=45.4326923076923, Blast_Score=360, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 49133; Mature: 49133

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICGSKTKSYLKSQNLKILGQGKLNGIVEISGAKNSALVLLASSLLTNEKIILENVPFLT
CCCCCHHHHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEEEHHHHCCCEEEEECCCCHH
DIEKMGNILKNLGVNLVRKNNQLEIDPTTISIKELPYELVKGLRASFFCIGALLTKFGEA
HHHHHHHHHHHCCCEEEECCCEEEECCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
QVPLPGGCNIGSRPIEEHINGLIALGAEIIIEKGIVKAKIRGNKNRLHGTHIKLNCPSVG
CCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEECCCCC
ATETLIMAASLAKGRTTIENAAREPEVQDLCQMLNKMGAKIYDSGKETIIIDGVNKLGGC
CHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCEEEEECCHHHCCC
THKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKS
CHHCCCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCEEEEEC
KEIKGVDIETAPFPGFPTDLQAPFTTLMTIANGESKITETIFENRMNHIYLLNEMGASIK
CCCCCCEEECCCCCCCCCCCCCCHHHHEEECCCCHHHHHHHHHCCCCEEEEEECCCCEEE
LNKNVAHIKGVKTINGMNLVGSDLRSSAALIIAGIIAKGSSNFYGLEHLDRGYENFELKL
ECCCCEEECCCEEECCCCHHCHHHHCCHHEEEEEHHHCCCCCCCCHHHHHCCCCCEEEEE
KNLGVKIIREISKNTFEENGYKIESKSENLSKLGAA
ECCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCC
>Mature Secondary Structure
MICGSKTKSYLKSQNLKILGQGKLNGIVEISGAKNSALVLLASSLLTNEKIILENVPFLT
CCCCCHHHHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEEEHHHHCCCEEEEECCCCHH
DIEKMGNILKNLGVNLVRKNNQLEIDPTTISIKELPYELVKGLRASFFCIGALLTKFGEA
HHHHHHHHHHHCCCEEEECCCEEEECCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
QVPLPGGCNIGSRPIEEHINGLIALGAEIIIEKGIVKAKIRGNKNRLHGTHIKLNCPSVG
CCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEECCCCC
ATETLIMAASLAKGRTTIENAAREPEVQDLCQMLNKMGAKIYDSGKETIIIDGVNKLGGC
CHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCEEEEECCHHHCCC
THKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKS
CHHCCCCCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCEEEEEC
KEIKGVDIETAPFPGFPTDLQAPFTTLMTIANGESKITETIFENRMNHIYLLNEMGASIK
CCCCCCEEECCCCCCCCCCCCCCHHHHEEECCCCHHHHHHHHHCCCCEEEEEECCCCEEE
LNKNVAHIKGVKTINGMNLVGSDLRSSAALIIAGIIAKGSSNFYGLEHLDRGYENFELKL
ECCCCEEECCCEEECCCCHHCHHHHCCHHEEEEEHHHCCCCCCCCHHHHHCCCCCEEEEE
KNLGVKIIREISKNTFEENGYKIESKSENLSKLGAA
ECCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA